CP-609754

DB12640InvestigationalSmall molecule

LNK 754 has been investigated in Mild Alzheimer's Disease.

Mechanism: Pharmacologically active on Protein farnesyltransferase subunit beta and Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Curator reviewed
Formula / weight: C₂₉H₂₂ClN₃O₂ · 479.96 g/mol (avg)
Code names: CP-609,754 · LNK-754 · OSI-754

Resolves to

Compound

Structure

InChIKeyJAHDAIPFBPPQHQ-GDLZYMKVSA-NSMILESCN1C=NC=C1[C@@](O)(C1=CC=C(Cl)C=C1)C1=CC=C2N(C)C(=O)C=C(C3=CC=CC(=C3)C#C)C2=C1

Targets

What you can answer from here — as of July 07, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with CP-609754, and which of those have an active Phase 3 trial?

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