Displaying drugs 476 - 500 of 795 in total
AB-201
AB-201 is a CAR-NK cell therapy targeted against HER2. It is under investigation for the treatment of HER2-positive cancers, including breast and gastric carcinomas.
Investigational
Matched Synonyms: … allogeneic cord blood-derived NK cells that have been genetically modified to express a HER2-directed CAR and …
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …
Cortisone
A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)
Experimental
Matched Description: … It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
AZD-2066
AZD2066 has been used in trials studying the treatment and basic science of Pain, Chronic Pain, Reflux Episodes, Neuropathic Pain, and Diabetic Neuropathy, among others.
Investigational
Matched Description: … Episodes, Neuropathic Pain, and Diabetic Neuropathy, among others. ... AZD2066 has been used in trials studying the treatment and basic science of Pain, Chronic Pain, Reflux …
CMX-2043
CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, Stable Coronary Artery Disease, and Percutaneous Coronary Intervention.
Investigational
Matched Description: … Stable Coronary Artery Disease, and Percutaneous Coronary Intervention. ... CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
SCB-2019
SCB-2019 is a recombinant trimeric S protein subunit vaccine candidate being investigated against COVID-19. This vaccine candidate resembles the native trimeric viral spike and is produced through mammalian cell-culture.
The vaccine was developed and tested by Clover Biopharmaceuticals AUS Pty Ltd.. As of June 2020, the company is pursuing a...
Investigational
Matched Description: … The vaccine was developed and tested by Clover Biopharmaceuticals AUS Pty Ltd.. ... This vaccine candidate resembles the native trimeric viral spike and is produced through mammalian cell-culture ... company is pursuing a randomized, double blind, placebo controlled study (NCT04405908) to test the safety and …
XMT-2056
XMT-2056 is a HER2-targeted antibody-drug conjugate (ADC) consisting of a HER2-targeted antibody conjugated with a stimulator of interferon genes (STING) agonist payload.
Investigational
Velafermin
Velafermin was a novel investigational protein therapeutic, also known as fibroblast growth factor-20 (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated activity in multiple animal models. Velafermin was investigated as a potential therapy for the prevention and treatment of oral mucositis by fostering the...
Investigational
Matched Synonyms: … RECOMBINANT HUMAN FIBROBLAST GROWTH FACTOR-20 ... FIBROBLAST GROWTH FACTOR 20 (HUMAN RECOMBINANT CG53135) …
Matched Description: … (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated ... Velafermin was a novel investigational protein therapeutic, also known as fibroblast growth factor-20 ... by fostering the regeneration and repair of the cells lining the gastrointestinal tract. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated ... Velafermin was a novel investigational protein therapeutic, also known as fibroblast growth factor-20 ... by fostering the regeneration and repair of the cells lining the gastrointestinal tract. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
INGN 201
INGN 201(Advexin) is a replication-impaired adenoviral vector that carries the p53 gene, has been evaluated in both preclinical and clinical trials. Advexin is a well-tolerated and efficacious treatment for numerous cancers, both as monotherapy and in combination with radiation and/or chemotherapy agents.
Investigational
Matched Description: … Advexin is a well-tolerated and efficacious treatment for numerous cancers, both as monotherapy and in ... combination with radiation and/or chemotherapy agents. ... replication-impaired adenoviral vector that carries the p53 gene, has been evaluated in both preclinical and …
PRO 2000
PRO 2000 is an investigational medicine that is not yet approved by the FDA for use outside of clinical trials. It is being studied for the prevention of HIV infection and other sexually transmitted diseases. This medicine does not cure HIV infection or AIDS and is being studied to reduce...
Investigational
Matched Description: … It is being studied for the prevention of HIV infection and other sexually transmitted diseases. ... This medicine does not cure HIV infection or AIDS and is being studied to reduce the risk of passing …
CAM-2029
CAM2029 is a new ready-to-use, long-acting octreotide formulation being developed for the long-term treatment of acromegaly, carcinoid syndrome and vasoactive intestinal peptide (VIP)-producing tumours. CAM2029 was found to provide long-acting release of octreotide resulting in a statistically significant suppression of a clinical biomarker insulin-like growth factor 1 (IGF-1) over the...
Investigational
Matched Description: … octreotide formulation being developed for the long-term treatment of acromegaly, carcinoid syndrome and …
AVXS-201
Withdrawn
OTX-2002
OTX-2002 is a bicistronic messenger ribonucleic acid (mRNA) encoding for ZF-DNMT and ZF-KRAB proteins, encapsulated in a lipid nanoparticle (LNP).
Investigational
Matched Description: … OTX-2002 is a bicistronic messenger ribonucleic acid (mRNA) encoding for ZF-DNMT and ZF-KRAB proteins …
ISB 2001
ISB 2001 is a T cell-engaging antibody that targets BCMA, CD38, and CD3.
Investigational
Matched Description: … ISB 2001 is a T cell-engaging antibody that targets BCMA, CD38, and CD3. …
CLZ-2002
CLZ-2002 consists of allogeneic mesenchymal stem cells derived neuronal regeneration-promoting cells.
Investigational
Polysorbate 60
Experimental
Matched Synonyms: … PEG-20 sorbitan palmitostearate ... Polyoxyethylene (20) sorbitan monostearate ... Polyoxyethylene 20 sorbitan monostearate …
Hydroxyprogesterone
Experimental
Matched Categories: … Progesterone and Derivatives ... hydroxyprogesterone and estrogen ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Odronextamab
Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody currently evaluated for the treatment of relapsed/refractory (R/R) B-Cell non-Hodgkin lymphoma (NHL).[A254187,A254197] Preliminary studies have shown that in patients with R/R NHL, the use of odronextamab does not lead to the development of neurologic toxicity; however, it can...
Investigational
Matched Description: … [A254187] In December 2020, the FDA placed a partial clinical hold and requested the drug developer, …
WRR-204
Experimental
CX-2009
CX-2009 is under investigation in clinical trial NCT03149549 (PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors).
Investigational
Matched Description: … CX-2009 is under investigation in clinical trial NCT03149549 (PROCLAIM-CX-2009: A Trial to Find Safe and …
ABO-202
Investigational
CRS-207
Investigational
TCN-202
Investigational
Displaying drugs 476 - 500 of 795 in total