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Displaying drugs 476 - 500 of 746 in total
Ligufalimab
Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47. It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … .4-chain), disulfide with human-mus musculus monoclonal ak117 .kappa. ... Immunoglobulin g4 (225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal ak117 .gamma …
Itepekimab
Itepekimab is under investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-il-33 Mab) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)).
Investigational
Matched Synonyms: … Immunoglobulin igg4 (230-proline), anti-(human interleukin 33) (human monoclonal regn3500 .gamma.4-chain ... ), disulfide with human monoclonal regn3500 .kappa. …
Matched Description: … investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Interleukin-7
Interleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer.
Investigational
Matched Synonyms: … Interleukin-7 human recombinant ... Recombinant human interleukin-7 ... Glycosylated recombinant human interleukin-7 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Livmoniplimab
Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)).
Investigational
Matched Synonyms: … (human monoclonal abbv-151 .gamma.4-chain), disulfide with human monoclonal abbv-151 .kappa. ... Immunoglobulin g4 (234-proline), anti-(human protein garp-transforming growth factor .beta.1 complex) …
Matched Description: … Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and …
Matched Description: … Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and …
Gefurulimab
Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN SERUM ALBUMIN) (HUMAN-LAMA GLAMA MONOCLONAL ALXN1720 SINGLE-DOMAIN ... COMPLEMENT C5) (HUMAN-LAMA GLAMA MONOCLO ... VHH FRAGMENT) FUSION PROTEIN WITH PEPTIDE LINKER (SYNTHETIC 15 AMINO-ACID) FUSION PROTEIN WITH ANTI-(HUMAN …
Matched Description: … Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in …
Matched Description: … Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in …
Tuvirumab
Investigational
Matched Synonyms: … Immunoglobulin g 1 (human monoclonal pe1-1 anti-hepatitis b virus surface antigen), disulfide with human ... Immunoglobulin g 1 (human monoclonal pe1-1 anti-hepatitis b virus surface antigen), disulfide with human ... Immunoglobulin g1, anti-(hepatitis b virus surface antigen) (human monoclonal pe1-1 .gamma.1-chain), …
Timolumab
Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).
Investigational
Matched Synonyms: … protein-1 (VAP-1) ... recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion …
Matched Description: … vascular adhesion protein-1 (VAP-1). ... Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … vascular adhesion protein-1 (VAP-1). ... Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Denecimig
Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9.
Investigational
Matched Synonyms: … Immunoglobulin G4 [230-proline,de-449-lysine], anti-(human blood-coagulation factor IX) (human clone ... .229′)-bis(disulfide) with anti-(human bl ... 0365-0001-9985 γ4-chain), disulfide with human clone 0365-0001-9985 κ-chain, (228.fwdarw.226′),(231.fwdarw …
Frexalimab
Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis).
Investigational
Matched Synonyms: … Immunoglobulin G1 (272-arginine,325-alanine), anti-(human CD40 ligand) (human-mus musculus monoclonal ... SAR441344 gamma1-chain), disulfide with human-mus musculus monoclonal SAR441344 kappa-chain, dimer …
Matched Description: … Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab …
Matched Description: … Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab …
Ezabenlimab
Investigational
Matched Synonyms: … .gamma.4-chain), disulfide with human monoclonal bi754091 .kappa. ... Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human monoclonal bi754091 ... Anti-pd-1 monoclonal antibody bi 754091 …
Amlitelimab
Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).
Investigational
Matched Synonyms: … 2d10 .gamma.4-chain), disulfide with human monoclonal ky1005-2d10 .kappa. ... Immunoglobulin g4 (235-proline,242-glutamic acid), anti-(human ox40 ligand) (human monoclonal ky1005- …
Matched Description: … Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and ... Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and …
Matched Description: … Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and ... Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and …
Apitegromab
Apitegromab is under investigation in clinical trial NCT03921528 (An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy).
Investigational
Matched Synonyms: … -015 .gamma.4-chain), disulfide with human monoclonal srk-015 .lambda. ... Immunoglobulin g4 (234-proline), anti-(human progrowth differentiation factor 8) (human monoclonal srk …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
EDI-200
EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1.
Investigational
Matched Synonyms: … HUMAN IMMUNOGLOBULIN G1 CONSTANT REGION - HUMAN ECTODYSPLASIN-A1 RECEPTOR-BINDING DOMAIN FUSION PROTEIN …
Matched Description: … human receptor binding domain of ectodysplasin-A1. ... EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … human receptor binding domain of ectodysplasin-A1. ... EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Talditercept alfa
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … protein with adnectin, anti-(human growth differentiation factor 8) (human clone bms-986089 fibronectin ... Bivalent Anti-Human Myostatin Adnectin-Igg1 ... Bms-986089 (fully human anti-myostatin adnectin) …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …
Serplulimab
Investigational
Matched Synonyms: … Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal ... hlx10 .gamma.4-chain), disulfide with human-mus musculus monoclonal hlx10 .kappa. …
Matched Categories: … PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Categories: … PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Onfekafusp alfa
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion ... protein with human tumor necrosis factor .alpha., trimer …
Acimtamig
Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct.
Investigational
Matched Synonyms: … tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct ... Immunoglobulin, anti-(human FcγRIIIa receptor) (human heavy chain V-D-J region) fusion protein with peptide ... linker (GGS)3 fusion protein with immunoglobulin anti-(human CD30 antigen) (human-Mus musculus single-chain …
Matched Description: … Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vixarelimab
Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Prurigo Nodularis).
Investigational
Matched Synonyms: … (human monoclonal kpl-716 .gamma.-chain), disulfide with human monoclonal kpl-716 .lambda. ... Immunoglobulin g (234-proline,303-glutamine), anti-(human oncostatin m receptor subunit .beta.) …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and …
Avizakimab
Avizakimab is under investigation in clinical trial NCT03371251 (Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care).
Investigational
Matched Synonyms: … musculus monoclonal bos161721 .gamma.1-chain), disulfide with human-mus musculus monoclonal bos161721 ... Immunoglobulin g1 (251-tyrosine,253-threonine,255-glutamic acid), anti-(human interleukin 21) (human-mus …
Zimberelimab
Investigational
Matched Synonyms: … .gamma.4-chain), disulfide with human monoclonal ab122 .lambda. ... Immunoglobulin g4(231-proline), anti-(human programmed cell death protein 1) (human monoclonal ab122 ... Anti-pd-1 monoclonal antibody gls-010 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Teropavimab
Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection).
Investigational
Matched Synonyms: … ) (human monoclonal 8c11-62a12 .gamma.1-chain), disulfide with human monoclonal 8c11-62a12 .kappa. ... Immunoglobulin g1 (434-leucine,440-serine), anti-(human immunodeficiency virus 1 envelope protein gp120env …
Matched Description: … With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection). ... Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination …
Matched Description: … With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection). ... Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination …
Finotonlimab
Finotonlimab is under investigation in clinical trial NCT04560894 (SCT-I10A Plus SCT510 Versus Sorafenib as First-line Therapy for Advanced Hepatocellular Carcinoma).
Investigational
Matched Synonyms: … Immunoglobulin g4 (226-proline), anti-(human programmed cell death 1) (human-mus musculus monoclonal ... sct-i10a .gamma.4-chain), disulfide with human-mus musculus monoclonal sct-i10a .kappa. …
AOC-1020
AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotide targeting DUX4.
Investigational
Matched Synonyms: … An antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector ... function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotide …
Matched Description: … AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting ... , effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA …
Matched Description: … AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting ... , effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA …
NGN-401
NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2 (MECP2). Developed by Neurogene Inc., it is being investigated for the treatment of Rett syndrome.
Investigational
Matched Synonyms: … a full-length human methyl cytosine binding protein 2 (MECP2) ... virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and …
Matched Description: … a full-length human methyl cytosine binding protein 2 (MECP2). ... virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and …
Matched Description: … a full-length human methyl cytosine binding protein 2 (MECP2). ... virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and …
Displaying drugs 476 - 500 of 746 in total