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Displaying drugs 5076 - 5100 of 5749 in total

(3,4,8b-Trimethyl-3-oxido-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-3-ium-7-yl) N-(2-ethylphenyl)carbamate

Experimental
Matched Name: … (3,4,8b-Trimethyl-3-oxido-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-3-ium-7-yl) N-(2-ethylphenyl)carbamate …
Matched Iupac: … 5-{[(2-ethylphenyl)carbamoyl]oxy}-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-1-ium-1-olate …

Cannabidivarin

Cannabidivarin, also known as cannabidivarol or CBDV, is a non-psychoactive cannabinoid found within DB14009. It is one of over 100 cannabinoids identified from the Cannabis plant that can modulate the physiological activity of cannabis, or marijuana . Compared to its homolog, DB09061, CBDV is shortened by two methyl (CH2) groups...
Investigational
Matched Synonyms: … 2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-propylbenzene-1,3-diol …
Matched Iupac: … 2-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-5-propylbenzene-1,3-diol …
Matched Description: … acid. ... Notably, both [DB09061] and CBDV have demonstrated anticonvulsant activity in animal and human models ... CBD and CBDV have been shown to dose-dependently activate and then desensitize TRPV1 as well as TRPV2 …

Indium cation In-111

Experimental
Matched Synonyms: … Indium cation In-111 (3+) …
Matched Iupac: … (111In)indium(3+) ion …

Atuzaginstat

Atuzaginstat is under investigation in clinical trial NCT03823404 (GAIN Trial: Phase 2/3 Study of COR388 in Subjects With Alzheimer's Disease).
Investigational
Matched Synonyms: … N-((3s)-7-amino-2-oxo-1-(2,3,6- trifluorophenoxy)heptan-3-yl)cyclopentanecarboxamide …
Matched Description: … Atuzaginstat is under investigation in clinical trial NCT03823404 (GAIN Trial: Phase 2/3 Study of COR388 …

AGI-134

AGI-134 is under investigation in clinical trial NCT03593226 (Study to Evaluate Safety & Tolerability of AGI-134 in Solid Tumour).
Investigational
Matched Synonyms: … 2R)-1-((2-(5-((3-(((2R,3R,4R,5S,6R)-5-(((2S,3R,4S,5S,6R)-3,5-DIHYDROXY-6-(HYDROXYMETHYL)-4-(((2R,3R,4S ... ,5R,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL)OXY)OXAN-2-YL)OXY)-3-ACETAMIDO-4-HYDROXY-6-(HYDROXYMETHYL …

Nemvaleukin alfa

Investigational
Matched Synonyms: … 132), fused via peptidyl linker (133GSGGGS138) to human interleukin 2 receptor α-chain fragment (139-303 ... human) fusion protein with peptide linker (gsgggs) fusion protein with 1-165-interleukin 2 receptor .alpha ... comprised of a circularly-permuted interleukin-2 (IL-2) with the extracellular domain of IL-2 receptor alpha …

4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine

Experimental
Matched Name: … 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine …
Matched Iupac: … 4-(2,5-dichlorothiophen-3-yl)pyrimidin-2-amine …

5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione

Experimental
Matched Name: … 5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione …
Matched Iupac: … 5-methoxy-1,2-dimethyl-3-(phenoxymethyl)-4,7-dihydro-1H-indole-4,7-dione …

1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane

Experimental
Matched Name: … 1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane …
Matched Iupac: … }ethyl]carbamoyl}butanoic acid ... (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(2S)-1-hydroxy-3-(4-nitrophenoxy)propan-2-yl]sulfanyl …

N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine

Experimental
Matched Name: … N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine …
Matched Iupac: … ethyl(3-{[3-(propylamino)propyl]amino}propyl)amine …

N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine

Experimental
Matched Name: … N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine …
Matched Iupac: … N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine …

5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine

Experimental
Matched Name: … 5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine …
Matched Iupac: … 5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine …

(3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE

Experimental
Matched Name: … (3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE …
Matched Iupac: … (3R)-3-(fluoromethyl)-7-(thiomorpholine-4-sulfonyl)-1,2,3,4-tetrahydroisoquinoline …

4-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINE

Experimental
Matched Name: … 4-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINE …
Matched Iupac: … 4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidine …

1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE

Experimental
Matched Name: … 1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE …
Matched Iupac: … 1-benzyl-3-[(4-methoxyphenyl)amino]-4-phenyl-2,5-dihydro-1H-pyrrole-2,5-dione …

1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine

Experimental
Matched Name: … 1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine …
Matched Iupac: … [(9-ethyl-9H-carbazol-3-yl)methyl](methyl)amine …

3(S)-AMINO-4-PHENYL-BUTAN-2(S)-OL

Experimental
Matched Name: … 3(S)-AMINO-4-PHENYL-BUTAN-2(S)-OL …
Matched Iupac: … (2S,3S)-3-amino-4-phenylbutan-2-ol …

2-[(2',3',4'-TRIFLUOROBIPHENYL-2-YL)OXY]ETHANOL

Experimental
Matched Name: … 2-[(2',3',4'-TRIFLUOROBIPHENYL-2-YL)OXY]ETHANOL …
Matched Iupac: … 2-({2',3',4'-trifluoro-[1,1'-biphenyl]-2-yl}oxy)ethan-1-ol …

(1S)-1-AMINO-2-(1H-INDOL-3-YL)ETHANOL

Experimental
Matched Name: … (1S)-1-AMINO-2-(1H-INDOL-3-YL)ETHANOL …
Matched Iupac: … (1S)-1-amino-2-(1H-indol-3-yl)ethan-1-ol …

(5-Hydroxy-6-methyl-4-{[(E)-(3-oxo-1,2-oxazolidin-4-ylidene)amino]methyl}-3-pyridinyl)methyl dihydrogen phosphate

Experimental
Matched Name: … (5-Hydroxy-6-methyl-4-{[(E)-(3-oxo-1,2-oxazolidin-4-ylidene)amino]methyl}-3-pyridinyl)methyl dihydrogen …
Matched Iupac: … acid ... {[5-hydroxy-6-methyl-4-({[(4E)-3-oxo-1,2-oxazolidin-4-ylidene]amino}methyl)pyridin-3-yl]methoxy}phosphonic …

(1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE

Experimental
Matched Name: … (1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE …
Matched Iupac: … (2S)-1-(1H-indol-3-yl)-3-({5-[(1E)-2-(pyridin-4-yl)ethenyl]pyridin-3-yl}oxy)propan-2-amine …

N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide

Experimental
Matched Name: … N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide …
Matched Iupac: … N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide …

(2S)-2-({6-[(3-Amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methyl-1-butanol

Experimental
Matched Name: … (2S)-2-({6-[(3-Amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methyl-1-butanol …
Matched Iupac: … (2S)-2-({6-[(3-amino-5-chlorophenyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}amino)-3-methylbutan-1-ol …

HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM

Experimental
Matched Name: … HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM …
Matched Iupac: … (2Z)-N-(3-nitrophenyl)-4-{3-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}-2,5-dihydropyrimidin-2-imine …

Danicopan

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematologic disease characterized by hemolysis, thrombophilia, and bone marrow dysfunction.[A263501,L50417] Both hemolysis and thrombophilia are mediated primarily by the complement system. Standard therapy for PNH involves the use of complement C5 inhibitors (e.g. eculizumab, ravulizumab) which are effective in mitigating complement-mediated intravascular...
Approved
Investigational
Matched Synonyms: … (2S,4R)-1-(2-(3-acetyl-5-(2-methylpyrimidine-5-yl)-1H-indazol-1-yl)acetyl)-N-(6-bromopyridine-2-yl)-4 ... (2S,4R)-1-(2-(3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl)acetyl)-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine …
Matched Iupac: … (2S,4R)-1-{2-[3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl]acetyl}-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine …
Matched Description: … hemoglobinuria (PNH) is a rare acquired hematologic disease characterized by hemolysis, thrombophilia, and ... [A263501,L50417] Both hemolysis and thrombophilia are mediated primarily by the complement system. ... eculizumab], [ravulizumab]) which are effective in mitigating complement-mediated intravascular hemolysis and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic ... Antineoplastic and Immunomodulating Agents …
Displaying drugs 5076 - 5100 of 5749 in total