Displaying drugs 501 - 525 of 797 in total
SIG-205
SIG-205 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral vector to express human native alpha-L-iduronidase enzyme (hIDUA), encapsulated within two-layer modified alginate spheres
Investigational
OTL-203
OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor …
Matched Description: … OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor …
Velafermin
Velafermin was a novel investigational protein therapeutic, also known as fibroblast growth factor-20 (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated activity in multiple animal models. Velafermin was investigated as a potential therapy for the prevention and treatment of oral mucositis by fostering the...
Investigational
Matched Synonyms: … RECOMBINANT HUMAN FIBROBLAST GROWTH FACTOR-20 ... FIBROBLAST GROWTH FACTOR 20 (HUMAN RECOMBINANT CG53135) …
Matched Description: … (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated ... Velafermin was a novel investigational protein therapeutic, also known as fibroblast growth factor-20 ... by fostering the regeneration and repair of the cells lining the gastrointestinal tract. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated ... Velafermin was a novel investigational protein therapeutic, also known as fibroblast growth factor-20 ... by fostering the regeneration and repair of the cells lining the gastrointestinal tract. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
E-2012
E-2012 is a gamma secretase modulator that is being evaluated as a potential new treatment for Alzheimer's disease.
Investigational
Matched Categories: … Gamma Secretase Inhibitors and Modulators …
VB-201
VB-201 is under investigation in clinical trial NCT01001468 (Study to Assess VB-201 in Patients With Psoriasis).
Investigational
AB-201
AB-201 is a CAR-NK cell therapy targeted against HER2. It is under investigation for the treatment of HER2-positive cancers, including breast and gastric carcinomas.
Investigational
Matched Synonyms: … allogeneic cord blood-derived NK cells that have been genetically modified to express a HER2-directed CAR and …
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …
AUM-601
AUM-601 is a highly selective pan-TRK(tropomyosin receptor kinase). It is currently being investigated in clinical trials for the treatment of cancer.
Investigational
INGN 201
INGN 201(Advexin) is a replication-impaired adenoviral vector that carries the p53 gene, has been evaluated in both preclinical and clinical trials. Advexin is a well-tolerated and efficacious treatment for numerous cancers, both as monotherapy and in combination with radiation and/or chemotherapy agents.
Investigational
Matched Description: … Advexin is a well-tolerated and efficacious treatment for numerous cancers, both as monotherapy and in ... combination with radiation and/or chemotherapy agents. ... replication-impaired adenoviral vector that carries the p53 gene, has been evaluated in both preclinical and …
PRO 2000
PRO 2000 is an investigational medicine that is not yet approved by the FDA for use outside of clinical trials. It is being studied for the prevention of HIV infection and other sexually transmitted diseases. This medicine does not cure HIV infection or AIDS and is being studied to reduce...
Investigational
Matched Description: … It is being studied for the prevention of HIV infection and other sexually transmitted diseases. ... This medicine does not cure HIV infection or AIDS and is being studied to reduce the risk of passing …
CAM-2029
CAM2029 is a new ready-to-use, long-acting octreotide formulation being developed for the long-term treatment of acromegaly, carcinoid syndrome and vasoactive intestinal peptide (VIP)-producing tumours. CAM2029 was found to provide long-acting release of octreotide resulting in a statistically significant suppression of a clinical biomarker insulin-like growth factor 1 (IGF-1) over the...
Investigational
Matched Description: … octreotide formulation being developed for the long-term treatment of acromegaly, carcinoid syndrome and …
AVXS-201
Withdrawn
OTX-2002
OTX-2002 is a bicistronic messenger ribonucleic acid (mRNA) encoding for ZF-DNMT and ZF-KRAB proteins, encapsulated in a lipid nanoparticle (LNP).
Investigational
Matched Description: … OTX-2002 is a bicistronic messenger ribonucleic acid (mRNA) encoding for ZF-DNMT and ZF-KRAB proteins …
ISB 2001
ISB 2001 is a T cell-engaging antibody that targets BCMA, CD38, and CD3.
Investigational
Matched Description: … ISB 2001 is a T cell-engaging antibody that targets BCMA, CD38, and CD3. …
CLZ-2002
CLZ-2002 consists of allogeneic mesenchymal stem cells derived neuronal regeneration-promoting cells.
Investigational
AZD-2066
AZD2066 has been used in trials studying the treatment and basic science of Pain, Chronic Pain, Reflux Episodes, Neuropathic Pain, and Diabetic Neuropathy, among others.
Investigational
Matched Description: … Episodes, Neuropathic Pain, and Diabetic Neuropathy, among others. ... AZD2066 has been used in trials studying the treatment and basic science of Pain, Chronic Pain, Reflux …
CMX-2043
CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, Stable Coronary Artery Disease, and Percutaneous Coronary Intervention.
Investigational
Matched Description: … Stable Coronary Artery Disease, and Percutaneous Coronary Intervention. ... CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
SCB-2019
SCB-2019 is a recombinant trimeric S protein subunit vaccine candidate being investigated against COVID-19. This vaccine candidate resembles the native trimeric viral spike and is produced through mammalian cell-culture.
The vaccine was developed and tested by Clover Biopharmaceuticals AUS Pty Ltd.. As of June 2020, the company is pursuing a...
Investigational
Matched Description: … As of June 2020, the company is pursuing a randomized, double blind, placebo controlled study (NCT04405908 ... ) to test the safety and immunogenicity of the vaccine. ... The vaccine was developed and tested by Clover Biopharmaceuticals AUS Pty Ltd.. …
XMT-2056
XMT-2056 is a HER2-targeted antibody-drug conjugate (ADC) consisting of a HER2-targeted antibody conjugated with a stimulator of interferon genes (STING) agonist payload.
Investigational
Solanezumab
Solanezumab is under investigation for the treatment of Dementia, Alzheimers Disease, and Alzheimers Disease, Familial.
Investigational
Matched Description: … Solanezumab is under investigation for the treatment of Dementia, Alzheimers Disease, and Alzheimers …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
KAb201
Investigational
Algestone
Experimental
Matched Categories: … Progesterone and Derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
WRR-204
Experimental
Displaying drugs 501 - 525 of 797 in total