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Displaying drugs 5451 - 5475 of 9339 in total

Alpha-Methylene Adenosine Monophosphate

Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(methyl)phosphinic acid …

Guanosine 3'-monophosphate

Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Cetrelimab

Cetrelimab is under investigation in clinical trial NCT03547037 (A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of JNJ-63723283, an Anti-Programmed Cell Death (PD)-1 Monoclonal Antibody, as Monotherapy or in Combination With Erdafitinib in Japanese Participants With Advanced Solid Cancers).
Investigational

PLN-74809

PLN-74809 is a small-molecule that dually inhibits both αvβ6 and αvβ1 to treat both idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC) . The compound was granted orphan drug designation by the US FDA in August 2018 for treatment of IPF, and Pliant Therapeutics recently raised $100 million in...
Investigational
Matched Description: … PLN-74809 is a small-molecule that dually inhibits both αvβ6 and αvβ …

N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide

Experimental
Matched Name: … N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide …
Matched Iupac: … N-(1-hydroxy-2-methylpropan-2-yl)-1-methyl-3-{1H-pyrrolo[2,3-b]pyridin-2-yl}-1H-indole-5-carboxamide …

3-[5-(1H-IMIDAZOL-1-YL)-7-METHYL-1H-BENZIMIDAZOL-2-YL]-4-[(PYRIDIN-2-YLMETHYL)AMINO]PYRIDIN-2(1H)-ONE

Experimental
Matched Name: … 3-[5-(1H-IMIDAZOL-1-YL)-7-METHYL-1H-BENZIMIDAZOL-2-YL]-4-[(PYRIDIN-2-YLMETHYL)AMINO]PYRIDIN-2(1H)-ONE …
Matched Iupac: … 3-[6-(1H-imidazol-1-yl)-4-methyl-1H-1,3-benzodiazol-2-yl]-4-{[(pyridin-2-yl)methyl]amino}-1,2-dihydropyridin ... -2-one …

2-(4-(AMINOMETHYL)PIPERIDIN-1-YL)-N-(3_CYCLOHEXYL-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)ACETAMIDE

Experimental
Matched Name: … 2-(4-(AMINOMETHYL)PIPERIDIN-1-YL)-N-(3_CYCLOHEXYL-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)ACETAMIDE …
Matched Iupac: … 2-[4-(aminomethyl)piperidin-1-yl]-N-{3-cyclohexyl-4-oxo-2H,4H-indeno[1,2-c]pyrazol-5-yl}acetamide …

N-[1-(2,6-dimethoxybenzyl)piperidin-4-yl]-4-sulfanylbutanamide

Experimental

GW-493838

GW493838 has been used in trials studying the treatment of Neuropathic Pain.
Investigational
Matched Iupac: … (2S,3S,4R,5R)-2-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-5-{6-[(4-chloro-2-fluorophenyl)amino]-9H-purin-9- …

ADL5859

ADL5859 is a novel, oral compound that targets the Delta opioid receptor. Delta receptor agonists are thought to offer benefits over other approaches to the management of pain.
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

RAPA-501-Allo

RAPA-501-ALLO is composed of T-cells extracted from healthy volunteers; these cells are then reprogrammed ex vivo in a process that involves de-differentiation and re-differentiation.
Investigational

BAP5191

Investigational

MRT5005

MRT5005 is a human cystic fibrosis transmembrane conductance regulator (hCFTR) messenger RNA (mRNA) complexed with branched polyethyleneimine (bPEI).
Investigational

CHF5633

CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational

(1-Benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid

Experimental
Matched Name: … (1-Benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid …
Matched Iupac: … 2-(1-benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid …

2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Benzothiazole

Experimental
Matched Name: … 2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Benzothiazole …
Matched Iupac: … (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(5-methyl-1,3-benzothiazol-2-yl)oxane-3,4,5-triol …

5-[(4-Methylphenyl)Sulfanyl]-2,4-Quinazolinediamine

Experimental
Matched Name: … 5-[(4-Methylphenyl)Sulfanyl]-2,4-Quinazolinediamine …
Matched Iupac: … 5-[(4-methylphenyl)sulfanyl]quinazoline-2,4-diamine …

2-Amino-3-(Cystein-S-Yl)-Isoxazolidin-5-Yl-Acetic Acid

Experimental
Matched Name: … 2-Amino-3-(Cystein-S-Yl)-Isoxazolidin-5-Yl-Acetic Acid …
Matched Iupac: … (2R)-2-amino-3-{[(3R,5R)-5-[(S)-amino(carboxy)methyl]-1,2-oxazolidin-3-yl]sulfanyl}propanoic acid …

4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid

Experimental
Matched Name: … 4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid …
Matched Iupac: … 4-{5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl}benzoic acid …

2-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINE

Experimental
Matched Name: … 2-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINE …
Matched Iupac: … 5-(propan-2-yl)-2-[(3S)-1,2,3,4-tetrahydroisoquinolin-3-yl]-1,3-thiazole-4-carboxylic acid …

5-Iodouracil

Experimental
Matched Name: … 5-Iodouracil …
Matched Iupac: … 5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione …

JNJ-54175446

JNJ-54175446 is under investigation in clinical trial NCT02933762 (A Study in Healthy Participants to Evaluate the Effect of JNJ-54175446 on Amyloid Biomarkers and Cytokine Profiles in Cerebrospinal Fluid and Plasma).
Investigational
Matched Iupac: … 2-[(4R)-5-[2-chloro-3-(trifluoromethyl)benzoyl]-4-methyl-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridin ... -1-yl]-5-fluoropyrimidine …

MRT5201

Investigational

NPT520-34

Investigational

ART5803

ART5803 is a humanized one-armed monoclonal antibody with a high affinity for the NMDA receptor.
Investigational
Displaying drugs 5451 - 5475 of 9339 in total