Displaying drugs 526 - 550 of 1405 in total
Rosnilimab
Rosnilimab is under investigation in clinical trial NCT06041269 (A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Rheumatoid Arthritis (RENOIR)).
Investigational
Matched Synonyms: … .gamma.1-chain), disulfide with human-mus musculus monoclonal anb030 .kappa. ... Immunoglobulin g1, anti-(human programmed cell death protein 1) (human-mus musculus monoclonal anb030 …
Matched Description: … Rosnilimab is under investigation in clinical trial NCT06041269 (A Study of Efficacy and Safety of Rosnilimab …
Matched Description: … Rosnilimab is under investigation in clinical trial NCT06041269 (A Study of Efficacy and Safety of Rosnilimab …
Apolizumab
Apolizumab is a humanized monoclonal antibody that is being studied as a treatment for hematologic cancers.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN HISTOCOMPATIBILITY ANTIGEN HLA-DR) (HUMAN-MOUSE MONOCLONAL HU1D10.GAMMA ... (SUB 1)-CHAIN), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL HU1D10 LIGHT CHAIN, DIMER …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Unasnemab
Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human repulsive guidance molecule rgma) (human-mus musculus clone rh116a3 .gamma ... .1-chain), disulfide with human-mus musculus clone rh116a3 .kappa. …
Matched Description: … Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety …
Matched Description: … Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety …
Galegenimab
Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration (AMD)).
Investigational
Matched Synonyms: … fhtr2163 .gamma.1-chain), disulfide with human-mus musculus monoclonal fhtr2163 .kappa. ... Immunoglobulin igg1 fab fragment, anti-(human serine proteinase htra1) (human-mus musculus monoclonal …
Matched Description: … Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and …
Matched Description: … Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and …
Apitegromab
Apitegromab is under investigation in clinical trial NCT03921528 (An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy).
Investigational
Matched Synonyms: … -015 .gamma.4-chain), disulfide with human monoclonal srk-015 .lambda. ... Immunoglobulin g4 (234-proline), anti-(human progrowth differentiation factor 8) (human monoclonal srk …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Briquilimab
Briquilimab is a humanized aglycosylated IgG1 kappa monoclonal antibody targeting CD117 (cKit).
Investigational
Matched Synonyms: … .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL JSP191 .KAPPA. ... IMMUNOGLOBULIN G1 (297-GLUTAMINE), ANTI-(HUMAN C-KIT RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JSP191 …
Litifilimab
Litifilimab is under investigation in clinical trial NCT05531565 (A Study to Assess the Efficacy and Safety of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) And/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations and Refractory And/or Intolerant to Antimalarial Therapy).
Investigational
Matched Synonyms: … .gamma.1-chain), disulfide with human-mus musculus monoclonal biib059 .kappa. ... Immunoglobulin g1, anti-(human blood dendritic cell antigen 2) (human-mus musculus monoclonal biib059 …
Matched Description: … And/or Intolerant to Antimalarial Therapy). ... Litifilimab is under investigation in clinical trial NCT05531565 (A Study to Assess the Efficacy and ... of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) And …
Matched Description: … And/or Intolerant to Antimalarial Therapy). ... Litifilimab is under investigation in clinical trial NCT05531565 (A Study to Assess the Efficacy and ... of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) And …
Tetracycline
Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Synonyms: … (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl …
Matched Iupac: … (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene …
Matched Description: … exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and ... It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane …
Matched Mixtures name: … Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride ... Pylera 140 mg/125 mg/125 mg Hartkapseln …
Matched Categories: … Alimentary Tract and Metabolism ... tetracycline and oleandomycin ... Antiinfectives and Antiseptics for Local Oral Treatment ... Ophthalmological and Otological Preparations ... lansoprazole, tetracycline and metronidazole …
Matched Products: … MeaStem First Aid and Antibiotic …
Matched Iupac: … (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene …
Matched Description: … exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and ... It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane …
Matched Mixtures name: … Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride ... Pylera 140 mg/125 mg/125 mg Hartkapseln …
Matched Categories: … Alimentary Tract and Metabolism ... tetracycline and oleandomycin ... Antiinfectives and Antiseptics for Local Oral Treatment ... Ophthalmological and Otological Preparations ... lansoprazole, tetracycline and metronidazole …
Matched Products: … MeaStem First Aid and Antibiotic …
Methoxy PEG-12 retinamide
Experimental
Matched Synonyms: … Methoxy PEG-12 all-trans-retinamide …
Matched Name: … Methoxy PEG-12 retinamide …
Matched Name: … Methoxy PEG-12 retinamide …
Colestilan chloride
Colestilan is an ingredient in the EMA-withdrawn product BindRen.
Approved
Investigational
Withdrawn
Matched Synonyms: … Colestilan chloride …
Matched Name: … Colestilan chloride …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Name: … Colestilan chloride …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
PX-12
PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor growth in animal models. Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated as a potential cancer treatment...
Investigational
Matched Name: … PX-12 …
Matched Description: … Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated ... stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits ... Initial trials correlated doses of Px-12 with increased patient survival. …
Matched Description: … Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated ... stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits ... Initial trials correlated doses of Px-12 with increased patient survival. …
Atibuclimab
Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN CD14 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IC14 .GAMMA.4-CHAIN), DISULFIDE ... IC14, (RECOMBINANT CHIMERIC MAB AGAINST HUMAN CD14) ... WITH HUMAN-MUS MUSCULUS MONOCLONAL IC14 .KAPPA. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Befovacimab
Investigational
Matched Synonyms: … Immunoglobulin g2, anti-(human tissue factor pathway inhibitor) (human monoclonal 1093884 .gamma.2-chain ... ), disulfide with human monoclonal 1093884 .lambda. ... Human tissue factor pathway inhibitor-neutralizing antibody (bay 1093884) …
Garadacimab
Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line).
Investigational
Matched Synonyms: … Immunoglobulin G4, anti-(human blood-coagulation factor viia) (human monoclonal CSL312 gamma4-chain), ... disulfide with human monoclonal CSL312 lambda-chain, dimer …
Matched Description: … Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and …
Matched Description: … Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and …
Tagitanlimab
Investigational
Matched Synonyms: … monoclonal kla167 .gamma.1-chain), disulfide with human monoclonal kla167 .kappa. ... Immunoglobulin g1 (237-alanine,238-alanine,240-alanine), anti-(human programmed death-ligand 1) (human …
Amlitelimab
Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).
Investigational
Matched Synonyms: … 2d10 .gamma.4-chain), disulfide with human monoclonal ky1005-2d10 .kappa. ... Immunoglobulin g4 (235-proline,242-glutamic acid), anti-(human ox40 ligand) (human monoclonal ky1005- …
Matched Description: … Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and ... Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and …
Matched Description: … Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and ... Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and …
Nadofaragene firadenovec
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon …
Matched Description: … interferon alfa-2b (IFNα2b). ... [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and …
Matched Categories: … Cellular and Gene Therapy ... Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Matched Description: … interferon alfa-2b (IFNα2b). ... [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and …
Matched Categories: … Cellular and Gene Therapy ... Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Tubocurarine
Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to coat the tips of hunting arrows and darts, which were typically derived from plants of the genera Chondrodendron and Strychnos....
Approved
Matched Synonyms: … 7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraranium …
Matched Description: … number of plant-derived alkaloids, including [morphine] and [papaverine]. ... Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid ... darts, which were typically derived from plants of the genera _Chondrodendron_ and _Strychnos_. …
Matched Salts name: … Tubocurarine chloride pentahydrate …
Matched Products: … Tubocurarine Chloride Inj 3mg/ml ... Tubocurarine Chloride Inj 3mg/ml USP …
Matched Description: … number of plant-derived alkaloids, including [morphine] and [papaverine]. ... Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid ... darts, which were typically derived from plants of the genera _Chondrodendron_ and _Strychnos_. …
Matched Salts name: … Tubocurarine chloride pentahydrate …
Matched Products: … Tubocurarine Chloride Inj 3mg/ml ... Tubocurarine Chloride Inj 3mg/ml USP …
Lumiliximab
Lumiliximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug. It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE antibody, for the potential treatment of allergic conditions. Lumiliximab was developed by IDEC Pharmaceuticals, which was acquired by Biogen. Clinical trials for...
Investigational
Matched Synonyms: … 152 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .KAPPA. ... 152 .GAMMA.1-CHAIN), DISULPHIDE WITH HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .KAPPA. ... IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC- …
Matched Description: … Clinical trials for CLL were terminated in 2010, and for allergic asthma in 2007. ... It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Clinical trials for CLL were terminated in 2010, and for allergic asthma in 2007. ... It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cholestyramine
Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water.
Approved
Investigational
Matched Products: … ESTRAMIN TOZ, 12 ADET ... COLESTYRAMIN 1A PHARMA 4G …
Serplulimab
Investigational
Matched Synonyms: … hlx10 .gamma.4-chain), disulfide with human-mus musculus monoclonal hlx10 .kappa. ... Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Vixarelimab
Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Prurigo Nodularis).
Investigational
Matched Synonyms: … (human monoclonal kpl-716 .gamma.-chain), disulfide with human monoclonal kpl-716 .lambda. ... Immunoglobulin g (234-proline,303-glutamine), anti-(human oncostatin m receptor subunit .beta.) …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and …
(10E,12Z)-octadecadienoic acid
Experimental
Matched Synonyms: … 10-trans-12-cis-CLA ... 10-trans-12-cis-linoleic acid ... (10E,12Z)-octadeca-10,12-dienoic acid …
Matched Name: … (10E,12Z)-octadecadienoic acid …
Matched Iupac: … (10E,12Z)-octadeca-10,12-dienoic acid …
Matched Name: … (10E,12Z)-octadecadienoic acid …
Matched Iupac: … (10E,12Z)-octadeca-10,12-dienoic acid …
Glutamine hydroxamate
Experimental
Matched Synonyms: … gamma-Glutamyl hydroxamate ... Glutamate-gamma-hydroxamate ... Glutamyl-gamma-hydroxamate …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 526 - 550 of 1405 in total