Displaying drugs 551 - 575 of 1921 in total
Cevidoplenib
Investigational
Matched Synonyms: … Methanone, cyclopropyl(5-((4-(4-(((4s)-4-hydroxy-2-isoxazolidinyl)methyl)-3-methyl-1h-pyrazol-1-yl)-2 ... -pyrimidinyl)amino)-1-methyl-1h-indol-3-yl)- …
Matched Iupac: … (4S)-2-[(1-{2-[(3-cyclopropanecarbonyl-1-methyl-1H-indol-5-yl)amino]pyrimidin-4-yl}-3-methyl-1H-pyrazol ... -4-yl)methyl]-1,2-oxazolidin-4-ol …
Matched Iupac: … (4S)-2-[(1-{2-[(3-cyclopropanecarbonyl-1-methyl-1H-indol-5-yl)amino]pyrimidin-4-yl}-3-methyl-1H-pyrazol ... -4-yl)methyl]-1,2-oxazolidin-4-ol …
ABSK-012
Investigational
Matched Synonyms: … ]-2-pyridinyl]-N-methyl- ... 3-(5-cyano-4-(cyclopropylamino)pyridin-2-yl)-1-(6-formyl-5-((4-methyl-2-oxopiperazin-1-yl)methyl)pyridin ... N′-[5-Cyano-4-(cyclopropylamino)-2-pyridinyl]-N-[6-formyl-5-[(4-methyl-2-oxo-1-piperazinyl)methyl]-2- …
Matched Iupac: … 3-[5-cyano-4-(cyclopropylamino)pyridin-2-yl]-1-{6-formyl-5-[(4-methyl-2-oxopiperazin-1-yl)methyl]pyridin …
Matched Iupac: … 3-[5-cyano-4-(cyclopropylamino)pyridin-2-yl]-1-{6-formyl-5-[(4-methyl-2-oxopiperazin-1-yl)methyl]pyridin …
Citraconic acid
Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid, or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid.
Experimental
Matched Synonyms: … Methyl-maleinsäure ... 2-Methyl-2-butenedioic acid ... (Z)-2-Methyl-2-butenedioic acid …
Panobinostat
Panobinostat is an oral deacetylace (DAC) inhibitor approved on February 23, 2015 by the FDA for the treatment of multiple myeloma. The approval was accelerated based on progression-free survival, therefore confirmatory trials by the sponsor to demonstrate clinical efficacy in multiple myeloma treatment are in progress of being conducted. Panobinostat...
Approved
Investigational
Matched Synonyms: … (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide ... 2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-(2-METHYL-1H-INDOL-3-YL)ETHYL)AMINO)METHYL)PHENYL)-, (2E)- …
Matched Iupac: … (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide …
Matched Description: … Panobinostat acts as a non-selective histone deacetylase inhibitor (pan-HDAC inhibitor) and it is the …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide …
Matched Description: … Panobinostat acts as a non-selective histone deacetylase inhibitor (pan-HDAC inhibitor) and it is the …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Bis(2,2-dimethylpropanoyloxymethyl) VK-0214
Investigational
Matched Synonyms: … methyl)phosphinylidene)bis(oxymethylene)) ester ... )methyl)phosphinylidene)bis(oxymethylene)) ester ... 2,2-dimethylpropanoic acid 1,1'-((((4-((4-hydroxy-3-(phenylmethyl)phenyl)methyl)-3,5-dimethylphenoxy) …
Matched Iupac: … {[({4-[(3-benzyl-4-hydroxyphenyl)methyl]-3,5-dimethylphenoxy}methyl)({[(2,2-dimethylpropanoyl)oxy]methoxy ... })phosphoryl]oxy}methyl 2,2-dimethylpropanoate …
Matched Iupac: … {[({4-[(3-benzyl-4-hydroxyphenyl)methyl]-3,5-dimethylphenoxy}methyl)({[(2,2-dimethylpropanoyl)oxy]methoxy ... })phosphoryl]oxy}methyl 2,2-dimethylpropanoate …
VK-0214
Investigational
Matched Synonyms: … Phosphonic acid, p-((4-((4-hydroxy-3-(phenylmethyl)phenyl)methyl)-3,5-dimethylphenoxy)methyl)- ... (((4-(3-benzyl-4-hydroxybenzyl)-3,5-dimethylphenyl)oxy)methyl)phosphonic acid ... ((4-(3-benzyl-4-hydroxybenzyl)-3,5-dimethylphenoxy)methyl)phosphonic acid …
Matched Iupac: … ({4-[(3-benzyl-4-hydroxyphenyl)methyl]-3,5-dimethylphenoxy}methyl)phosphonic acid …
Matched Iupac: … ({4-[(3-benzyl-4-hydroxyphenyl)methyl]-3,5-dimethylphenoxy}methyl)phosphonic acid …
Fosciclopirox
Investigational
Matched Synonyms: … ((6-cyclohexyl-4-methyl-2-oxopyridin-1(2h)-yl)oxy)methyl dihydrogen phosphate ... 6-cyclohexyl-4-methyl-1-((phosphonooxy)methoxy)-2(1h)-pyridinone ... 2(1h)-pyridinone, 6-cyclohexyl-4-methyl-1-((phosphonooxy)methoxy)- …
KF-1601
Investigational
Matched Synonyms: … N-(3-(2-cyanopropan-2-yl)-5-(4-methyl-1H-imidazol-1-yl)phenyl)-2-fluoro-4-methyl-5-((8-((1-methyl-1H-pyrazol ... Benzamide, N-[3-(1-cyano-1-methylethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl]-2-fluoro-4-methyl-5-[2-[ ... 8-[(1-methyl-1H-pyrazol-4-yl)amino]imidazo[1,2-a]pyridin-3-yl]ethynyl]- …
Matched Iupac: … N-[3-(1-cyano-1-methylethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl]-2-fluoro-4-methyl-5-(2-{8-[(1-methyl …
Matched Iupac: … N-[3-(1-cyano-1-methylethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl]-2-fluoro-4-methyl-5-(2-{8-[(1-methyl …
3-(10-methyl-9-anthryl)propanoic acid
Experimental
Matched Synonyms: … 3-(10-methyl-9-anthryl)propionic acid ... 3-(10-METHYL-ANTHRACEN-9-YL)-PROPIONIC ACID …
Matched Name: … 3-(10-methyl-9-anthryl)propanoic acid …
Matched Name: … 3-(10-methyl-9-anthryl)propanoic acid …
Idebenone
Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC). It has been proposed that by interacting with the ETC, idebenone increases ATP production required for mitochondrial function, reduces free radicals, inhibits lipid peroxidation, and...
Approved
Investigational
Matched Synonyms: … 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone ... 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone ... 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-p-benzoquinone …
Matched Description: … Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant ... and essential component of the Electron Transport Chain (ETC). ... consequently protects the lipid membrane and mitochondria from oxidative damage [A19768]. …
Matched Categories: … Enzymes and Coenzymes ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Description: … Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant ... and essential component of the Electron Transport Chain (ETC). ... consequently protects the lipid membrane and mitochondria from oxidative damage [A19768]. …
Matched Categories: … Enzymes and Coenzymes ... Psychostimulants, Agents Used for ADHD and Nootropics …
17alpha-methyl-4-hydroxynandrolone
17alpha-methyl-4-hydroxynandrolone is a schedule 3 anabolic steroid.
Illicit
Matched Synonyms: … 17α-Methyl-4-hydroxynandrolone …
Matched Name: … 17alpha-methyl-4-hydroxynandrolone …
Matched Description: … 17alpha-methyl-4-hydroxynandrolone is a schedule 3 anabolic steroid. …
Matched Name: … 17alpha-methyl-4-hydroxynandrolone …
Matched Description: … 17alpha-methyl-4-hydroxynandrolone is a schedule 3 anabolic steroid. …
6'-Methyl-Thiamin Diphosphate
Experimental
Matched Name: … 6'-Methyl-Thiamin Diphosphate …
Matched Iupac: … }ethyl)-4-methyl-1,3-thiazol-3-ium ... 3-[(4-amino-2,6-dimethylpyrimidin-5-yl)methyl]-5-(2-{[(hydrogen phosphonatooxy)(hydroxy)phosphoryl]oxy …
Matched Iupac: … }ethyl)-4-methyl-1,3-thiazol-3-ium ... 3-[(4-amino-2,6-dimethylpyrimidin-5-yl)methyl]-5-(2-{[(hydrogen phosphonatooxy)(hydroxy)phosphoryl]oxy …
Tris-Hydroxymethyl-Methyl-Ammonium
Experimental
Matched Name: … Tris-Hydroxymethyl-Methyl-Ammonium …
Matched Iupac: … tris(hydroxymethyl)(methyl)azanium …
Matched Iupac: … tris(hydroxymethyl)(methyl)azanium …
5-methyl-2'-deoxypseudouridine
Experimental
Matched Name: … 5-methyl-2'-deoxypseudouridine …
Matched Iupac: … 5-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 5-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
4-[(Isopropylamino)Methyl]Phenylalanine
Experimental
Matched Name: … 4-[(Isopropylamino)Methyl]Phenylalanine …
Matched Iupac: … (2S)-2-amino-3-(4-{[(propan-2-yl)amino]methyl}phenyl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-{[(propan-2-yl)amino]methyl}phenyl)propanoic acid …
Cocaine
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Synonyms: … Methyl benzoylecgonine ... [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester ... methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate …
Matched Iupac: … methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate …
Matched Description: … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in ... the eye, ear, nose, and throat. ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse …
Matched Categories: … Analgesics and Anesthetics …
Matched Iupac: … methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate …
Matched Description: … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in ... the eye, ear, nose, and throat. ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse …
Matched Categories: … Analgesics and Anesthetics …
(S)-Fluoxetine
An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration (the antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine).
Experimental
Matched Synonyms: … (S)-N-methyl-3-(4-trifluoromethylphenoxy)-3-phenylpropylamine ... (S)-N-methyl-γ-(4-trifluoromethylphenoxy)-3-phenylpropylamine ... (S)-N-methyl-3-(4-trifluoromethylphenyloxy)-3-(phenyl)propylamine …
Matched Iupac: … methyl[(3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amine …
Matched Description: … drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine). ... An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration (the antidepressant …
Matched Iupac: … methyl[(3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amine …
Matched Description: … drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine). ... An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration (the antidepressant …
AVA-4746
Investigational
Matched Synonyms: … )-4-methyl-, (.beta.s)- ... .-((((1-((2-chlorophenyl)methyl)-1,2-dihydro-4-hydroxy-5-methyl-2-oxo-3-pyridinyl)amino)carbonyl)amino ... (3s)-3-(((1-(2-chlorobenzyl)-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3yl)amino)carbonyl)amino-3-( …
Matched Iupac: … (3S)-3-[({1-[(2-chlorophenyl)methyl]-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3-yl}carbamoyl)amino …
Matched Iupac: … (3S)-3-[({1-[(2-chlorophenyl)methyl]-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3-yl}carbamoyl)amino …
Pimicotinib
Pimicotinib is under investigation in clinical trial NCT05804045 (Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor (MANEUVER)).
Investigational
Matched Synonyms: … 1-Pyrrolidinecarboxamide, 3,3-dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]- ... 3,3-Dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-2-oxo-1-pyrrolidinecarboxamide …
Benzyl N-[(2S)-5-(diaminomethylamino)-1-[[(2S)-4-fluoro-3-oxobutan-2-yl]amino]-1-oxopentan-2-yl]carbamate
Experimental
Matched Synonyms: … Benzoyl-arginine-alanine-methyl ketone …
Nequinate
Nequinate is an antiprotozoan used as a coccidiostat for poultry and rabbits. Nequinate belongs to the family of Hydroquinolones. These are compounds containing an hydrogenated quinoline bearing a ketone group.
Vet approved
Matched Synonyms: … Methyl benzoquate …
Matched Iupac: … methyl 7-(benzyloxy)-6-butyl-4-oxo-1,4-dihydroquinoline-3-carboxylate …
Matched Description: … Nequinate is an antiprotozoan used as a coccidiostat for poultry and rabbits. …
Matched Iupac: … methyl 7-(benzyloxy)-6-butyl-4-oxo-1,4-dihydroquinoline-3-carboxylate …
Matched Description: … Nequinate is an antiprotozoan used as a coccidiostat for poultry and rabbits. …
Avutometinib
Avutometinib (RO-5126766 free base) is under investigation in clinical trial NCT03875820 (Phase I Trial of VS-6063 and RO5126766.).
Investigational
Matched Synonyms: … )-N'-methyl- ... N-(3-fluoro-4-((4-methyl-2-oxo-7-((pyrimidin-2-yl)oxy)-2H-1-benzopyran-3-yl)methyl)pyridin-2-yl)-N'-methylsulfuric ... Sulfamide, N-(3-fluoro-4-((4-methyl-2-oxo-7-(2-pyrimidinyloxy)-2H-1-benzopyran-3-yl)methyl)-2-pyridinyl …
Matched Iupac: … 3-({3-fluoro-2-[(methylsulfamoyl)amino]pyridin-4-yl}methyl)-4-methyl-7-(pyrimidin-2-yloxy)-2H-chromen …
Matched Description: … RO-5126766 free base) is under investigation in clinical trial NCT03875820 (Phase I Trial of VS-6063 and …
Matched Iupac: … 3-({3-fluoro-2-[(methylsulfamoyl)amino]pyridin-4-yl}methyl)-4-methyl-7-(pyrimidin-2-yloxy)-2H-chromen …
Matched Description: … RO-5126766 free base) is under investigation in clinical trial NCT03875820 (Phase I Trial of VS-6063 and …
Displaying drugs 551 - 575 of 1921 in total