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Displaying drugs 5726 - 5750 of 10392 in total
N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine
Experimental
Matched Name: … N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine …
Matched Iupac: … 6-{[(3S,4R)-4-[(2-{[(3-chlorophenyl)methyl]amino}ethyl)amino]pyrrolidin-3-yl]methyl}-4-methylpyridin- ... 2-amine …
Matched Iupac: … 6-{[(3S,4R)-4-[(2-{[(3-chlorophenyl)methyl]amino}ethyl)amino]pyrrolidin-3-yl]methyl}-4-methylpyridin- ... 2-amine …
ADX10059
ADX10059 is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM). The orally available small molecule drug candidate, which is highly specific for mGluR5, was discovered at Addex in 2003. It is developed for the treatment of GERD, migraine and anxiety.
Investigational
Matched Description: … ADX10059 is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM). …
2'-C-methylcytidine
A nucleoside analog with anti-hepatitis C virus (HCV) activity. Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus viral replication.
Experimental
Matched Synonyms: … 2'C-Me-C ... 2'-C-Mecytosin …
Matched Name: … 2'-C-methylcytidine …
Matched Iupac: … 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1,2-dihydropyrimidin-2- …
Matched Description: … Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation …
Matched Name: … 2'-C-methylcytidine …
Matched Iupac: … 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1,2-dihydropyrimidin-2- …
Matched Description: … Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation …
(3R)-4-{[(3,4-dihydroxyphenyl)acetyl]oxy}-N-(2-formylindolizin-3-yl)-3-sulfino-D-valine
Experimental
Matched Name: … (3R)-4-{[(3,4-dihydroxyphenyl)acetyl]oxy}-N-(2-formylindolizin-3-yl)-3-sulfino-D-valine …
Matched Iupac: … (2S,3R)-4-{[2-(3,4-dihydroxyphenyl)acetyl]oxy}-2-[(2-formylindolizin-3-yl)amino]-3-methyl-3-[(S)-sulfino …
Matched Iupac: … (2S,3R)-4-{[2-(3,4-dihydroxyphenyl)acetyl]oxy}-2-[(2-formylindolizin-3-yl)amino]-3-methyl-3-[(S)-sulfino …
[4-(6-Chloro-Naphthalene-2-Sulfonyl)-Piperazin-1-Yl]-(3,4,5,6-Tetrahydro-2h-[1,4']Bipyridinyl-4-Yl)-Methanone
Experimental
Matched Name: … [4-(6-Chloro-Naphthalene-2-Sulfonyl)-Piperazin-1-Yl]-(3,4,5,6-Tetrahydro-2h-[1,4']Bipyridinyl-4-Yl)-Methanone …
Matched Iupac: … 1-[(6-chloronaphthalen-2-yl)sulfonyl]-4-[1-(pyridin-4-yl)piperidine-4-carbonyl]piperazine …
Matched Iupac: … 1-[(6-chloronaphthalen-2-yl)sulfonyl]-4-[1-(pyridin-4-yl)piperidine-4-carbonyl]piperazine …
Bradanicline
Bradanicline, a novel small molecule that modulates the activity of the neuronal nicotinic receptor (NNR) subtype known as alpha7(α7). Bradanicline belongs to a new class of drugs for the treatment of central nervous system diseases and disorders.
Investigational
Matched Iupac: … N-[(2S,3R)-2-[(pyridin-3-yl)methyl]-1-azabicyclo[2.2.2]octan-3-yl]-1-benzofuran-2-carboxamide …
Matched Salts cas: … 1111941-90-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 1111941-90-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Experimental
Matched Name: … 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE …
Matched Iupac: … 2-sulfanyl-N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.0^{2,7}]hexadeca-1(16),2(7),3,5,11,14- …
Matched Iupac: … 2-sulfanyl-N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.0^{2,7}]hexadeca-1(16),2(7),3,5,11,14- …
3-hydroxyanthranilic acid
An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
Experimental
Matched Synonyms: … 2-Amino-3-hydroxy-benzoic acid ... 2-Amino-3-Hydroxybenzoic Acid ... 3-Oxyanthranilic acid …
Matched Name: … 3-hydroxyanthranilic acid …
Matched Iupac: … 2-amino-3-hydroxybenzoic acid …
Matched Name: … 3-hydroxyanthranilic acid …
Matched Iupac: … 2-amino-3-hydroxybenzoic acid …
Xaliproden
Investigational
Matched Iupac: … 1-[2-(naphthalen-2-yl)ethyl]-4-[3-(trifluoromethyl)phenyl]-1,2,3,6-tetrahydropyridine …
2,3-Dihydroxy-Benzoic Acid
Experimental
2-Amino-3-Ketobutyric Acid
Experimental
Matched Name: … 2-Amino-3-Ketobutyric Acid …
Matched Iupac: … (2S)-2-amino-3-oxobutanoic acid …
Matched Iupac: … (2S)-2-amino-3-oxobutanoic acid …
PIK3CA
PIK3CA is under investigation in clinical trial NCT02957266 (Cervical Cancer Radiotherapy by Use of VMAT, Individualized Polyradiosensitization and Interstitial Brachytherapy).
Investigational
Matched Synonyms: … Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform …
(1S,2R)-2-[(2,5-difluorophenyl)carbamoyl]cyclopropanecarboxylic acid
Experimental
Matched Name: … (1S,2R)-2-[(2,5-difluorophenyl)carbamoyl]cyclopropanecarboxylic acid …
Matched Iupac: … (1S,2R)-2-[(2,5-difluorophenyl)carbamoyl]cyclopropane-1-carboxylic acid …
Matched Iupac: … (1S,2R)-2-[(2,5-difluorophenyl)carbamoyl]cyclopropane-1-carboxylic acid …
Andarine
Andarine is a non-steroidal selective androgen receptor modulator.
Experimental
Matched Synonyms: … (2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide …
Matched Iupac: … (2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide …
Matched Iupac: … (2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide …
2'-fluoro-2'-deoxyuridine 3'-monophosphate
Experimental
Matched Name: … 2'-fluoro-2'-deoxyuridine 3'-monophosphate …
Matched Iupac: … {[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-yl] …
Matched Iupac: … {[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-yl] …
Eprenetapopt
Eprenetapopt has been used in trials studying the treatment of Prostatic Neoplasms, Hematologic Neoplasms, and Platinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p53.
Investigational
Matched Synonyms: … 3-QUINUCLIDINONE, 2-(HYDROXYMETHYL)-2-(METHOXYMETHYL)- ... 1-Azabicyclo(2.2.2)octan-3-one, 2-(hydroxymethyl)-2-(methoxymethyl)- ... 2-hydroxymethyl-2-methoxymethyl-1-azabicyclo[2,2,2]octan-3-one …
Matched Iupac: … 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one …
Matched Iupac: … 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one …
Inositol 1,3,4,5-Tetrakisphosphate
Experimental
OCTANE-1,3,5,7-TETRACARBOXYLIC ACID
Experimental
5,10,15,20-Tetrakis(4-Sulpfonatophenyl)-21h,23h-Porphine
Experimental
Matched Iupac: … tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1,3(24),4,6,8,10,12,14,16(22),17,19-undecaen-2- …
N~2~-1,3-BENZOXAZOL-2-YL-3-CYCLOHEXYL-N-{2-[(4-METHOXYPHENYL)AMINO]ETHYL}-L-ALANINAMIDE
Experimental
Matched Name: … N~2~-1,3-BENZOXAZOL-2-YL-3-CYCLOHEXYL-N-{2-[(4-METHOXYPHENYL)AMINO]ETHYL}-L-ALANINAMIDE …
Matched Iupac: … (2S)-2-[(1,3-benzoxazol-2-yl)amino]-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]ethyl}propanamide …
Matched Iupac: … (2S)-2-[(1,3-benzoxazol-2-yl)amino]-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]ethyl}propanamide …
Isoquinoline, 7-(2-(3,6-dihydro-4-(3-(trifluoromethyl)phenyl)-1(2h)-pyridinyl)ethyl)-
Isoquinoline, 7-(2-(3,6-dihydro-4-(3-(trifluoromethyl)phenyl)-1(2h)-pyridinyl)ethyl)- is under investigation in clinical trial NCT00545454 (Activity and Safety of Oral Administration of SSR150106XB for the Reduction of Inflammation in Patients With Active Rheumatoid Arthritis).
Investigational
Matched Name: … Isoquinoline, 7-(2-(3,6-dihydro-4-(3-(trifluoromethyl)phenyl)-1(2h)-pyridinyl)ethyl)- …
Matched Iupac: … 7-(2-{4-[3-(trifluoromethyl)phenyl]-1,2,3,6-tetrahydropyridin-1-yl}ethyl)isoquinoline …
Matched Description: … Isoquinoline, 7-(2-(3,6-dihydro-4-(3-(trifluoromethyl)phenyl)-1(2h)-pyridinyl)ethyl)- is under investigation …
Matched Iupac: … 7-(2-{4-[3-(trifluoromethyl)phenyl]-1,2,3,6-tetrahydropyridin-1-yl}ethyl)isoquinoline …
Matched Description: … Isoquinoline, 7-(2-(3,6-dihydro-4-(3-(trifluoromethyl)phenyl)-1(2h)-pyridinyl)ethyl)- is under investigation …
D-Tryptophan
Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet. It is encoded in the standard genetic code as the codon UGG. The D-stereoisomer is occasionally found in naturally produced peptides (for example, the marine venom peptide contryphan). The distinguishing...
Experimental
Matched Synonyms: … (2R)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Matched Iupac: … (2R)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Matched Iupac: … (2R)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Clesacostat
Clesacostat is under investigation in clinical trial NCT04321031 (Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)).
Investigational
Matched Synonyms: … pyridin-2-yl)benzoic acid ... 4-(6-methoxy-4-(7-oxo-1-(propan-2-yl)-1,4,6,7-tetrahydrospiro(indazole-5,4'- piperidine)-1'-carbonyl) ... methoxy-4-((1,4,6,7-tetrahydro-1-(1-methylethyl)-7-oxospiro(5h-indazole-5,4'-piperidin)-1'-yl)carbonyl)-2- …
Mepiprazole
Mepiprazole is a minor tranquilizer with a phenylpiperazine structure. It is a pyrazolyl-alkyl-piperazine derivative. Mepiprazole mediates a weak inhibitory action on the uptake of 5-HT on hypothalamic neurons .
Mepiprazole is marketed in Spain for the treatment of anxiety neuroses.
It acts as a 5-HT2A and α1-adrenergic receptor antagonist, and...
Experimental
Matched Iupac: … 1-(3-chlorophenyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethyl]piperazine …
Matched Description: … Mepiprazole mediates a weak inhibitory action on the uptake of 5-HT on hypothalamic neurons [A7816]. ... It acts as a 5-HT2A and α1-adrenergic receptor antagonist, and has also been shown to inhibit the reuptake …
Matched Description: … Mepiprazole mediates a weak inhibitory action on the uptake of 5-HT on hypothalamic neurons [A7816]. ... It acts as a 5-HT2A and α1-adrenergic receptor antagonist, and has also been shown to inhibit the reuptake …
Isoleucine
An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of leucine. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.
Investigational
Nutraceutical
Matched Synonyms: … 2-Amino-3-methylvaleric acid ... (2S,3S)-2-Amino-3-methylpentanoic acid …
Matched Iupac: … (2S,3S)-2-amino-3-methylpentanoic acid …
Matched Mixtures name: … Aminosyn II 7% With 50% Dextrose ... Aminosyn II 8.5% With 50% Dextrose ... AMINOMIX 3 SOLÜSYON, 1000 ML …
Matched Iupac: … (2S,3S)-2-amino-3-methylpentanoic acid …
Matched Mixtures name: … Aminosyn II 7% With 50% Dextrose ... Aminosyn II 8.5% With 50% Dextrose ... AMINOMIX 3 SOLÜSYON, 1000 ML …
Displaying drugs 5726 - 5750 of 10392 in total