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Displaying drugs 5851 - 5875 of 7716 in total

Simtuzumab

Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis.
Investigational

WP-1122

WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.
Investigational
Matched Iupac: … (3R,4R,5R)-6-(acetyloxy)-4,5-dihydroxy-1-oxohexan-3-yl acetate …

Namn

Experimental
Matched Iupac: … 3-carboxy-1-[(2R,3R,4S,5R)-5-[(hydrogen phosphonatooxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1lambda5-pyridin …

Pterin Cytosine Dinucleotide

Experimental
Matched Iupac: … amino-4-oxo-6,7-disulfanyl-3H,4H,5H,5aH,8H,9aH,10H-pyrano[3,2-g]pteridin-8-yl]methoxy}[({[(2R,3S,4R,5R)-5- …

Dideoxyadenosine

Investigational
Matched Synonyms: … -d-glycero-pentofuranosyl)-9h-purin-6-amine ... 6-amino-9-(2',3'-dideoxy-.beta.-d-glycero-pentofuranosyl)purine …
Matched Iupac: … [(2S,5R)-5-(6-amino-9H-purin-9-yl)oxolan-2-yl]methanol …

PF-06842874

Investigational

6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE

Experimental
Matched Name: … 6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE …

STX-100

STX-100 is under investigation in clinical trial NCT01371305 (STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).
Investigational

Boron

Boron (B) is a chemical element with an atomic number 5 that belongs in the Period 2 and Group 13 in the periodic table. It is a low-abundant metalloid that is a poor electrical conductor at room temperature. Natural boron exists in 2 stable isotopes however pure boron is hard...
Experimental
Matched Description: … Boron (B) is a chemical element with an atomic number 5 that belongs in the Period 2 and Group 13 in …

2-Deoxy-2-Amino Glucitol-6-Phosphate

Experimental
Matched Name: … 2-Deoxy-2-Amino Glucitol-6-Phosphate …
Matched Iupac: … {[(2R,3S,4R,5S)-5-amino-2,3,4,6-tetrahydroxyhexyl]oxy}phosphonic acid …

Glucosaminyl-(Alpha-6)-D-Myo-Inositol

Experimental
Matched Name: … Glucosaminyl-(Alpha-6)-D-Myo-Inositol …
Matched Iupac: … (1R,2R,3R,4R,5S,6R)-6-{[(2R,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}cyclohexane …

(7as,12ar,12bs)-1,2,3,4,7a,12,12a,12b-Octahydroindolo[2,3-a]Quinolizin-7(6h)-One

Experimental

6-[N-(4-Ethyl-1,2,3,4-Tetrahydro-6-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine

Experimental
Matched Name: … 6-[N-(4-Ethyl-1,2,3,4-Tetrahydro-6-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine …
Matched Iupac: … 6-carbamimidoyl-N-[(4R)-4-ethyl-1,2,3,4-tetrahydroisoquinolin-6-yl]naphthalene-2-carboxamide …

AMG-208

AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and Oncology Patients, among others.
Investigational
Matched Synonyms: … 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline …
Matched Iupac: … 7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl}methoxy)quinoline …

LGD-2226

An androgen receptor modulator.
Experimental
Matched Synonyms: … 6-(Bis-(2,2,2-trifluoroethyl)amino)-4-trifluoromethyl-1H-quinolin-2-one …
Matched Iupac: … 6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one …

Selisistat

Selective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3, HDAC and NADase respectively). Enhances p53 acetylation in response to DNA damaging agents.
Experimental
Matched Synonyms: … rac-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide …
Matched Iupac: … 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide …

1,6-Fructose Diphosphate (Linear Form)

Experimental
Matched Iupac: … {[(3S,4S,5R)-3,4,5-trihydroxy-2-oxo-6-(phosphonooxy)hexyl]oxy}phosphonic acid …

3-(3-Methyl-2-buten-1-yl)-3H-purin-6-amine

Experimental
Matched Name: … 3-(3-Methyl-2-buten-1-yl)-3H-purin-6-amine …
Matched Iupac: … 3-(3-methylbut-2-en-1-yl)-3H-purin-6-amine …

3-isobutyl-1-methyl-7H-xanthine

Experimental

FDL169

Investigational
Matched Synonyms: … 2-(7-ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2(1H)-yl)-N-methyl-N-(2-methylbenzo(D)oxazol-6-yl)acetamide ... 2-(7-ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2(1H)-yl)-N-methyl-N-(2-methylbenzo[D]oxazol-6-yl)acetamide …
Matched Iupac: … -[7-ethoxy-4-(3-fluorophenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-methyl-N-(2-methyl-1,3-benzoxazol-6- …

LY-3499446

Investigational
Matched Synonyms: … 1-(4-(7-(2-amino-7-fluoro-1,3-benzothiazol-4-yl)-6-chloro-8-fluoro-quinazolin-4-yl)piperazin-1-yl)prop ... 2-propen-1-one, 1-(4-(7-2-amino-7-fluoro-4-benzothiazolyl)-6-chloro-8-fluoro-4-quinazolinyl)-1-piperazinyl …

(2R)-1-[4-({4-[(2,5-Dichlorophenyl)amino]-2-pyrimidinyl}amino)phenoxy]-3-(dimethylamino)-2-propanol

Experimental

(2S)-1-[4-({4-[(2,5-Dichlorophenyl)amino]-2-pyrimidinyl}amino)phenoxy]-3-(dimethylamino)-2-propanol

Experimental
Matched Iupac: … (2S)-1-[4-({6-[(2,5-dichlorophenyl)imino]-1,6-dihydropyrimidin-2-yl}amino)phenoxy]-3-(dimethylamino)propan …

(2S)-1-[4-({6-[(2,6-Difluorophenyl)amino]-4-pyrimidinyl}amino)phenoxy]-3-(dimethylamino)-2-propanol

Experimental
Matched Name: … (2S)-1-[4-({6-[(2,6-Difluorophenyl)amino]-4-pyrimidinyl}amino)phenoxy]-3-(dimethylamino)-2-propanol …
Matched Iupac: … (2S)-1-[4-({6-[(2,6-difluorophenyl)amino]pyrimidin-4-yl}amino)phenoxy]-3-(dimethylamino)propan-2-ol …

(2R)-1-[4-({6-[(2,6-Difluorophenyl)amino]-4-pyrimidinyl}amino)phenoxy]-3-(dimethylamino)-2-propanol

Experimental
Matched Name: … (2R)-1-[4-({6-[(2,6-Difluorophenyl)amino]-4-pyrimidinyl}amino)phenoxy]-3-(dimethylamino)-2-propanol …
Matched Iupac: … (2R)-1-[4-({6-[(2,6-difluorophenyl)amino]pyrimidin-4-yl}amino)phenoxy]-3-(dimethylamino)propan-2-ol …
Displaying drugs 5851 - 5875 of 7716 in total