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Displaying drugs 576 - 600 of 1294 in total
Linaclotide is a synthetic 14-amino acid cyclic peptide and first-in-class guanylate cyclase-C (G-CC) agonist.[A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide hormones that are endogenous activators of GC-C. It is also a homolog of a heat-stable enterotoxin derived from Escherichia coli, the first natural ligand...
Approved
Matched Synonyms: … (9-L-TYROSINE)HEAT-STABLE ENTEROTOXIN (ESCHERICHIA COLI)-(6-19)-PEPTIDE …
Matched Description: … [A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide ... [A260271] It gained EMA and Health Canada approval on November 26, 2012 [L47216] and December 3, 2013 ... Linaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism …
Investigational
Matched Synonyms: … Recombinant Human MG53 protein
Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. It was the first FDA-approved treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl...
Approved
Investigational
Matched Synonyms: … Immature human tripeptidyl-peptidase 1 ... Immature cell growth-inhibiting gene 1 protein ... Immature lysosomal pepstatin-insensitive protease
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and ... older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl peptidase …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Proteins
Parathyroid Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison Study of Pthrp and PTH to Treat Osteoporosis).
Investigational
Matched Synonyms: … 1-36 human parathyroid hormone-related protein ... 1-36 human humoral hypercalcemic factor ... Parathormone-related peptide (1-36) (human) …
Matched Name: … Parathyroid Hormone-Related Protein 1-36 …
Matched Description: … Study of Pthrp and PTH to Treat Osteoporosis). ... Parathyroid Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins
COL-118, a topical compound based on the SansRosa technology, for the treatment of redness associated with rosacea and other skin disorders. It is a believed to reduce erythema by constricting enlarged blood vessels in facial tissue. Col-118 is a unique formulation and presentation of Brimonidine, which is a selective alpha-2...
Investigational
Matched Name: … Col-118 …
Matched Description: … Col-118 is a unique formulation and presentation of Brimonidine, which is a selective alpha-2 adrenergic ... with rosacea and other skin disorders. ... COL-118, a topical compound based on the SansRosa technology, for the treatment of redness associated …
Experimental
Matched Name: … Bee pollen …
Investigational
Matched Name: … Recombinant human type VII collagen …
Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal growth factor receptor (EGFR). Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer.
Investigational
Matched International brands: … HuMax-EGFR ... HuMax-EGFR-2F8 ... HuMax-EGFR, 2F8 …
Matched Description: … Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer. ... Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, and dairy products . Studies on gastric digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated...
Approved
Experimental
Investigational
Matched Synonyms: … Pepsin, bovine
Matched Description: … a hormonally mediated process. ... and dairy products [L2358]. ... Stimulation of the pancreas and therefore enzymatic digestion of food is a tightly controlled and is …
Matched Mixtures name: … Betaine HCl and Pepsin ... Pancreatin and Enzyme Formula - Tablet ... Glutamic Acid Pepsin and Betaine Tablets …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... pepsin and acid preparations …
Sinecatechins is a botanical drug product for topical use. It is a partially purified fraction of the water extract of green tea leaves from Camellia sinensis, and is a mixture of catechins and other green tea components. Catechins constitute 85 to 95% (by weight) of the total drug substance which...
Approved
Investigational
Nutraceutical
Matched Synonyms: … CAMELLIA SINENSIS LEAF CATECHINS …
Matched Description: … is a mixture of catechins and other green tea components. ... It is a partially purified fraction of the water extract of green tea leaves from Camellia sinensis, and ... Gallocatechin gallate (GCg), Gallocatechin (GC), Catechin gallate (Cg), and Catechin (C). …
Ordesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease).
Investigational
Matched Synonyms: … Humax IL15 ... Humax-IL 15 ... Human IgG1 anti-IL-15 monoclonal antibody …
Matched Description: … Ordesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and ... Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Hedera helix leaf extract allergenic extract is used in allergenic testing.
Experimental
Matched Synonyms: … Hedera helix leaf
Matched Name: … Hedera helix leaf extract …
Matched Description: … Hedera helix leaf extract allergenic extract is used in allergenic testing. …
Matched Categories: … Cough and Cold Preparations ... Respiratory System …
Investigational
Matched Synonyms: … Recombinant human monoclonal IgM antibody targeting glucose regulated protein 78 …
Approved
Experimental
Matched Synonyms: … Rosemary leaf oil ... Rosmarinus officinalis leaf oil ... Rosmarinus officinalis (rosemary) leaf oil …
Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG.
Investigational
Matched Synonyms: … 1-118-Signal regulatory protein α (human) fusion protein with immunoglobulin G4 [128-proline] (human ... SIRPA-IGG4-FC FUSION PROTEIN TTI-622 …
Matched Description: … protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG. ... Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory …
Investigational
Matched Synonyms: … Protein cardiotrophin (human isoform 1) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins
MDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin-8) and may have potential application in oncology and inflammation. Trials will initially focus on studies to treat glioblastoma, a cancer of the central nervous system. Other possible indications include chronic obstructive pulmonary disease (COPD)...
Investigational
Matched International brands: … HuMax-Inflam …
Matched Description: … 8) and may have potential application in oncology and inflammation. ... In pre-clinical studies, HuMax-Inflam has been shown to inhibit tumor growth in tumor models using primary ... Other possible indications include chronic obstructive pulmonary disease (COPD) and pustular dermatoses …
Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis).
Investigational
Matched Synonyms: … VHH FRAGMENT) FUSION PROTEIN WITH PEPTIDE LINKER (SYNTHETIC 15 AMINO-ACID) FUSION PROTEIN WITH ANTI- ... (HUMAN COMPLEMENT C5) (HUMAN-LAMA GLAMA MONOCLO ... IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN SERUM ALBUMIN) (HUMAN-LAMA GLAMA MONOCLONAL ALXN1720 SINGLE-DOMAIN …
Matched Description: … Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in …
Plutavimab is under investigation in clinical trial NCT04900428 (Study to Evaluate a Single Intranasal Dose of STI-2099 (COVI-DROPS™) in Outpatient Adults With COVID-19 (UK)).
Investigational
Matched Synonyms: … glycoprotein receptor-binding domain) (human monoclonal sti-2020 .gamma.1-chain), disulfide with human ... Immunoglobulin g1 (234-alanine,235-alanine), anti-(severe acute respiratory syndrome coronavirus 2 spike …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Investigational
Matched Synonyms: … 75-133-interleukin 2 (125-serine) (human) fusion protein with peptide linker (gg) fusion protein with ... 75-133-Interleukin 2 [125-serine] (human) fusion protein with peptide linker (GG) fusion protein with ... 4-74-interleukin 2 (human) fusion protein with peptide linker (gsgggs) fusion protein with 1-165-interleukin …
Sibeprenlimab is under investigation in clinical trial NCT05248659 (Phase 2/3 Open-label Trial of Sibeprenlimab in the Treatment of Immunoglobulin a Nephropathy).
Investigational
Matched Synonyms: … Immunoglobulin g2, anti-(human proliferation-inducing ligand protein) (human monoclonal vis649 .gamma ... .2-chain), disulfide with human monoclonal vis649 .kappa. …
Ilex paraguariensis leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Ilex Paraguariensis Leaf Extract ... Mate' Leaf (Ilex Paraguariensis St. Hilaire) …
Matched Name: … Ilex paraguariensis leaf
Matched Description: … Ilex paraguariensis leaf is a plant/plant extract used in some OTC (over-the-counter) products. …
RBIO-101 is a recombinant adeno-associated virus vector encoding human CYP4V2 protein.
Investigational
Matched Synonyms: … recombinant adeno-associated virus vector encoding human CYP4V2 protein
Matched Description: … RBIO-101 is a recombinant adeno-associated virus vector encoding human CYP4V2 protein. …
Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas, and liver. The hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 . The main action of secretin is to stimulate the pancreas...
Approved
Matched Synonyms: … Human secretin ... Secretin human ... Secretin (human) …
Matched Name: … Secretin human
Matched Description: … Synthetic human secretin displays equivalent biological activity and properties as naturally-occurring ... , and liver. ... of pancreatic exocrine dysfunction and the diagnosis of gastrinoma, and facilitate the identification …
Matched Salts name: … Secretin human pentahydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins ... Nerve Tissue Proteins
Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type II collagen.
Investigational
Matched Synonyms: … Purified autologous type 1 regulatory T lymphocytes specific for human type II collagen …
Matched Name: … Col-Treg …
Matched Description: … Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type
Displaying drugs 576 - 600 of 1294 in total