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Displaying drugs 6001 - 6025 of 8681 in total
Epicillin
Experimental
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Recoflavone
Recoflavone has been used in trials studying the treatment of Acute Gastritis, Dry Eye Syndrome, and Chronic Gastritis.
Investigational
Matched Iupac: … 2-{[2-(3,4-dimethoxyphenyl)-5-methoxy-4-oxo-4H-chromen-7-yl]oxy}acetic acid …
Vepsitamab
Investigational
Matched Synonyms: … BISPECIFIC, ANTI-(HUMAN MUCIN 17) (HUMAN MONOCLONAL MUC17_CD3_ALT2 SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3- …
B7-H3-specific chimeric antigen receptor T cells
Investigational
Fenproporex
Fenproporex is an orally active stimulant drug, which was developed in the 1960s. It is used as an appetite suppressant and a treatment for obesity. It is listed as an illicit substance in many countries due to addiction issues and listed as a prohibited substance by the World Anti-Doping Agency....
Experimental
Illicit
Withdrawn
Matched Iupac: … 3-[(1-phenylpropan-2-yl)amino]propanenitrile …
Matched Description: … demonstrated easy in vivo cleavage of the N-2-cyanothyl substituent to yield amphetamine as a metabolite. [5] …
Matched Description: … demonstrated easy in vivo cleavage of the N-2-cyanothyl substituent to yield amphetamine as a metabolite. [5] …
LY-2811376
LY2811376 has been used in trials studying the basic science of Alzheimer's Disease.
Investigational
Matched Iupac: … (4S)-4-[2,4-difluoro-5-(pyrimidin-5-yl)phenyl]-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine …
Phosmet
Phosmet is a phthalimide-derived organophosphate. It is a non-specific insecticide. It is mainly used on apple trees to control codling moths. It is also used on other fruit crops, ornamentals, and vines to control aphids, suckers, mites, and fruit flies.
Vet approved
TU-514
Experimental
Matched Iupac: … (2R,3S,4R,5S)-3-hydroxy-5-[(hydroxycarbamoyl)methyl]-2-(hydroxymethyl)oxan-4-yl tetradecanoate …
P54
P54 reduces the inflammation associated with cancer/tumors, Crohn's disease, inflammatory bowel disease, osteoarthritis, and ulcerative colitis. It inhibits the induction of the enzyme NFkB, thereby inhibiting downstream inflammatory genes such as COX II and iNOS.
Investigational
AT-527
Investigational
Matched Iupac: … propan-2-yl (2S)-2-[({[(3R,4R,5R)-5-[2-amino-6-(methylamino)-9H-purin-9-yl]-4-fluoro-3-hydroxy-4-methyloxolan …
E59
E59 is a humanized IgG1 low affinity allergic reactivity inhibiting (LARI) monoclonal antibody. It was developed by Sixal Inc.
Investigational
2-Methyl-3-(2-Aminothiazolo)Propanal
Experimental
Matched Name: … 2-Methyl-3-(2-Aminothiazolo)Propanal …
Matched Iupac: … (2S)-3-(2-amino-1,3-thiazol-4-yl)-2-methylpropanal …
Matched Iupac: … (2S)-3-(2-amino-1,3-thiazol-4-yl)-2-methylpropanal …
3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE
Experimental
Matched Name: … 3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE …
Matched Iupac: … 3-(1H-1,3-benzodiazol-2-yl)-1H-indazole …
Matched Iupac: … 3-(1H-1,3-benzodiazol-2-yl)-1H-indazole …
3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE
Experimental
Matched Name: … 3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE …
Matched Iupac: … 3-[(naphthalen-1-yl)methoxy]pyridin-2-amine …
Matched Iupac: … 3-[(naphthalen-1-yl)methoxy]pyridin-2-amine …
Ala-geninthiocin
Ala-geninthiocin is a novel thiopeptide antibacterial compound derived from marine Streptomyces species. It has exhibited potent in vitro activity against gram-positive bacteria including Staphylococcus aureus, Bacillus subtilis, Mycobacterium smegmatis, and Micrococcus luteus.
Experimental
Matched Iupac: … dodecaazahexacyclo[39.2.1.1^{8,11}.1^{18,21}.1^{31,34}.0^{2,7}]heptatetraconta-1(43),2,4,6,8(47),10,18(46),20,31(45 …
(2s)-2-[(2,4-Dichloro-Benzoyl)-(3-Trifluoromethyl-Benzyl)-Amino]-3-Phenyl-Propionic Acid
Experimental
Matched Name: … (2s)-2-[(2,4-Dichloro-Benzoyl)-(3-Trifluoromethyl-Benzyl)-Amino]-3-Phenyl-Propionic Acid …
Matched Iupac: … (2S)-2-[1-(2,4-dichlorophenyl)-N-{[3-(trifluoromethyl)phenyl]methyl}formamido]-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-[1-(2,4-dichlorophenyl)-N-{[3-(trifluoromethyl)phenyl]methyl}formamido]-3-phenylpropanoic acid …
(4R)-4-(3-HYDROXYPHENYL)-N,N,7,8-TETRAMETHYL-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE
Experimental
Matched Name: … (4R)-4-(3-HYDROXYPHENYL)-N,N,7,8-TETRAMETHYL-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE …
Matched Iupac: … (4R)-4-(3-hydroxyphenyl)-N,N,7,8-tetramethyl-1,2,3,4-tetrahydroisoquinoline-2-carboxamide …
Matched Iupac: … (4R)-4-(3-hydroxyphenyl)-N,N,7,8-tetramethyl-1,2,3,4-tetrahydroisoquinoline-2-carboxamide …
N-{3-[(E)-(tert-butoxyimino)methyl]-4-chlorophenyl}-2-methylfuran-3-carbimidothioic acid
Experimental
Matched Name: … N-{3-[(E)-(tert-butoxyimino)methyl]-4-chlorophenyl}-2-methylfuran-3-carbimidothioic acid …
Matched Iupac: … N-{3-[(1E)-[(tert-butoxy)imino]methyl]-4-chlorophenyl}-2-methylfuran-3-carbothioamide …
Matched Iupac: … N-{3-[(1E)-[(tert-butoxy)imino]methyl]-4-chlorophenyl}-2-methylfuran-3-carbothioamide …
N4-Hydroxycytidine
N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions.[A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage. It has shown antiviral activity against Venezuelan equine encephalitis virus, and the human coronavirus HCoV-NL63 in vitro. N4-hydroxycytodine has been...
Experimental
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)-1,2-dihydropyrimidin-2- …
Matched Description: … [A193014] It is orally bioavailable in mice and distributes into tissue before becoming the active 5’ …
Matched Description: … [A193014] It is orally bioavailable in mice and distributes into tissue before becoming the active 5’ …
Diethyltryptamine
Diethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine.
Experimental
Illicit
Matched Synonyms: … 3-(2-Diethylaminoethyl)indole …
Matched Iupac: … diethyl[2-(1H-indol-3-yl)ethyl]amine …
Matched Iupac: … diethyl[2-(1H-indol-3-yl)ethyl]amine …
9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide
9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide is an inactive derivative of the antitumour agents N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 9-amino-DACA.
Experimental
Matched Synonyms: … 9-amino-N-(3-dimethylaminopropyl)acridine-4-carboxamide …
Matched Name: … 9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide …
Matched Iupac: … 9-amino-N-[3-(dimethylamino)propyl]acridine-4-carboxamide …
Matched Description: … 9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide is an inactive derivative of the antitumour …
Matched Name: … 9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide …
Matched Iupac: … 9-amino-N-[3-(dimethylamino)propyl]acridine-4-carboxamide …
Matched Description: … 9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide is an inactive derivative of the antitumour …
Triapine
Triapine has been used in trials studying the treatment of Leukemia, Lung Cancer, Kidney Cancer, Prostate Cancer, and Pancreatic Cancer, among others.
Investigational
Matched Synonyms: … 3-Aminopyridine-2-carboxaldehyde thiosemicarbazone …
Matched Iupac: … [(E)-[(3-aminopyridin-2-yl)methylidene]amino]thiourea …
Matched Iupac: … [(E)-[(3-aminopyridin-2-yl)methylidene]amino]thiourea …
XomaZyme-791
Investigational
Tidutamab
Tidutamab is under investigation in clinical trial NCT04590781 (Safety and Efficacy of Xmab18087 ± Pembrolizumab in Advanced Merkel Cell Carcinoma or Extensive-stage Small Cell Lung Cancer).
Investigational
Displaying drugs 6001 - 6025 of 8681 in total