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Displaying drugs 6101 - 6125 of 6806 in total

Z-Val-Ala-Asp fluoromethyl ketone

Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which can be used directly with purified enzymes. It does not require an esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(O-Me) fluoromethyl ketone.
Experimental
Matched Synonyms: … N-[(Benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxo-2-butanyl]-L-alaninamide …
Matched Iupac: … (3S)-3-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoic …

Acazicolcept

Investigational

Mapatumumab

Mapatumumab is under investigation in clinical trial NCT00094848 (Study of TRM-1 (TRAIL-R1 Monoclonal Antibody) in Subjects With Relapsed or Refractory Non-hodgkin's Lymphoma (NHL)).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy ... Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy ... Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receptor 4)) (human monoclonal trm-1 heavy …

[[4-(Aminomethyl)Phenyl]Amino]Oxo-Acetic Acid,

Experimental
Matched Name: … [[4-(Aminomethyl)Phenyl]Amino]Oxo-Acetic Acid, …
Matched Iupac: … {[4-(aminomethyl)phenyl]carbamoyl}formic acid …

N-(2,6-Diflouro-Benzyl)-4-Sulfamoyl-Benzamide

Experimental
Matched Name: … N-(2,6-Diflouro-Benzyl)-4-Sulfamoyl-Benzamide …
Matched Iupac: … N-[(2,6-difluorophenyl)methyl]-4-sulfamoylbenzamide …

N-(2,3-DIFLUORO-BENZYL)-4-SULFAMOYL-BENZAMIDE

Experimental
Matched Name: … N-(2,3-DIFLUORO-BENZYL)-4-SULFAMOYL-BENZAMIDE …
Matched Iupac: … N-[(2,3-difluorophenyl)methyl]-4-sulfamoylbenzamide …

(2S)-hydroxy(4-hydroxyphenyl)ethanoic acid

Experimental
Matched Name: … (2S)-hydroxy(4-hydroxyphenyl)ethanoic acid …
Matched Iupac: … (2S)-2-hydroxy-2-(4-hydroxyphenyl)acetic acid …

2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid

Metabolic product of biphenyl; from Pseudomonas putida.
Experimental

2,2-bis(4-hydroxy-3-tert-butylphenyl)propane

TBD has been used in trials studying the treatment of Adenocarcinoma.
Investigational
Matched Name: … 2,2-bis(4-hydroxy-3-tert-butylphenyl)propane …
Matched Iupac: … 2-tert-butyl-4-[2-(3-tert-butyl-4-hydroxyphenyl)propan-2-yl]phenol …

Mipsagargin

Mipsagargin has been used in trials studying the treatment of Prostate Cancer, Prostatic Neoplasms, Advanced Solid Tumors, Glioblastoma Multiforme, and Hepatocellular Carcinoma, among others.
Investigational
Matched Iupac: … trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-7-(octanoyloxy)-2-oxo-2H,3H,3aH,4H,5H,6H,6aH,7H,8H,9bH-azuleno[4,5 ... (2S)-2-[(4S)-4-[(4S)-4-[(4S)-4-[(2S)-3-[(12-{[(3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-3,3a-dihydroxy ... -b]furan-4-yl]oxy}-12-oxododecyl)carbamoyl]-2-aminopropanamido]-4-carboxybutanamido]-4-carboxybutanamido ... ]-4-carboxybutanamido]pentanedioic acid …

Gitoformate

Experimental
Matched Iupac: … (1S,2S,5S,7R,10R,11S,13S,14R,15R)-5-{[(2R,4S,5R,6R)-5-{[(2S,4S,5R,6R)-5-{[(2S,4S,5R,6R)-4,5-bis(formyloxy ... )-6-methyloxan-2-yl]oxy}-4-(formyloxy)-6-methyloxan-2-yl]oxy}-4-(formyloxy)-6-methyloxan-2-yl]oxy}-11 ... -hydroxy-2,15-dimethyl-14-(5-oxo-2,5-dihydrofuran-3-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan- …

N,N-[2,5-O-[Dibenzyl]-glucaryl]-DI-[isoleucyl-amido-methane]

Experimental

Compound 5, 2-(Naphthalen-1-Yl-Oxalyl-Amino)-Benzoicacid

Experimental
Matched Name: … Compound 5, 2-(Naphthalen-1-Yl-Oxalyl-Amino)-Benzoicacid …

N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide

N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide is a solid. This compound belongs to the naphthalenes. These are compounds containing a naphthalene moiety, which consists of two fused benzene rings. The proteins that N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide targets include cyclin-A2 and cyclin-dependent kinase 2.
Experimental
Matched Name: … N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide …
Matched Iupac: … N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(naphthalen-2-yl)acetamide …
Matched Description: … N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide is a solid. ... The proteins that N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide targets include cyclin-A2 …

2-amino-3-(4-amino-1H-indol-3-yl)propanoic acid

Experimental
Matched Name: … 2-amino-3-(4-amino-1H-indol-3-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-amino-1H-indol-3-yl)propanoic acid …

4-bromo-3-hydroxy-3-methyl butyl diphosphate

Experimental
Matched Name: … 4-bromo-3-hydroxy-3-methyl butyl diphosphate …
Matched Iupac: … ({[(3R)-4-bromo-3-hydroxy-3-methylbutoxy](hydroxy)phosphoryl}oxy)phosphonic acid …

(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid

Experimental
Matched Name: … (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid …

(2-BROMOETHYL)(2-'FORMYL-4'-AMINOPHENYL) ACETATE

Experimental
Matched Name: … (2-BROMOETHYL)(2-'FORMYL-4'-AMINOPHENYL) ACETATE …
Matched Iupac: … 2-bromoethyl 2-(4-amino-2-formylphenyl)acetate …

Vocacapsaicin

Investigational
Matched Synonyms: … 1-piperidinecarboxylic acid, 2-((methylamino)methyl)-, 2-methoxy-4-((((6e)-8-methyl-1-oxo-6-nonen-1-yl ... 2-methoxy-4-(((6e)-8-methylnon-6-enamido)methyl)phenyl (2rs)-2-((methylamino)methyl)piperidine-1-carboxylate …
Matched Iupac: … 2-methoxy-4-{[(6E)-8-methylnon-6-enamido]methyl}phenyl 2-[(methylamino)methyl]piperidine-1-carboxylate …

Dichlorophen

Dichlorophen is an antimicrobial agent shown to exert activity against cestodes, protozoa, fungi, and bacteria. It is often combined with toluene to remove parasites including ascarids, tapeworm, and hookworm from dogs and cats.
Experimental
Vet approved
Matched Synonyms: … 2,2'-Methylenebis(4-chlorophenol) …
Matched Iupac: … 4-chloro-2-[(5-chloro-2-hydroxyphenyl)methyl]phenol …

1-((1R,2S)-1-{2-[2-(4-CHLOROPHENYL)-1,3-BENZOXAZOL-7-YL]ETHYL}-2-HYDROXYPROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE

Experimental
Matched Name: … 1-((1R,2S)-1-{2-[2-(4-CHLOROPHENYL)-1,3-BENZOXAZOL-7-YL]ETHYL}-2-HYDROXYPROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE …
Matched Iupac: … 1-[(3S,4S)-1-[2-(4-chlorophenyl)-1,3-benzoxazol-7-yl]-4-hydroxypentan-3-yl]-1H-imidazole-4-carboxamide …

(2S)-1-(Dimethylamino)-3-(4-{[4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-pyrimidinyl]amino}phenoxy)-2-propanol

Experimental
Matched Name: … (2S)-1-(Dimethylamino)-3-(4-{[4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-pyrimidinyl]amino}phenoxy)-2-propanol …
Matched Iupac: … (2S)-1-(dimethylamino)-3-{4-[(4-{2-methylimidazo[1,2-a]pyridin-3-yl}pyrimidin-2-yl)amino]phenoxy}propan …

(1R)-N,6-DIHYDROXY-7-METHOXY-2-[(4-METHOXYPHENYL)SULFONYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-1-CARBOXAMIDE

Experimental
Matched Name: … (1R)-N,6-DIHYDROXY-7-METHOXY-2-[(4-METHOXYPHENYL)SULFONYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-1-CARBOXAMIDE …
Matched Iupac: … (1R)-N,6-dihydroxy-7-methoxy-2-(4-methoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide …

Finotonlimab

Finotonlimab is under investigation in clinical trial NCT04560894 (SCT-I10A Plus SCT510 Versus Sorafenib as First-line Therapy for Advanced Hepatocellular Carcinoma).
Investigational
Matched Synonyms: … (226-proline), anti-(human programmed cell death 1) (human-mus musculus monoclonal sct-i10a .gamma.4- …

RU84687

RU84687 is a subnanomolar and Src SH2 selective binder.
Experimental
Matched Synonyms: … N-acetyl-N-[1-(1,1'-biphenyl-4-ylmethyl)-2-oxoazepan-3-yl]-3-formyl-O-phosphonotyrosinamide …
Matched Iupac: … {4-[(2S)-2-{[(3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-formylphenoxy …
Displaying drugs 6101 - 6125 of 6806 in total