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Displaying drugs 6126 - 6150 of 9061 in total

GL-2045

Investigational

MTI-201

Investigational

KTH-222

Investigational

STM-217

Investigational

JLK-247

JLK-247 is an adeno-associated viral vector serotype 9 (AAV9)-mediated gene replacement therapy for the treatment of Sanfilippo Syndrome Type C or MPS IIIC.
Investigational

OTL-201

OTL-201 is an investigational hematopoietic stem cell (HSC) gene therapy being developed by Orchard Therapeutics for the treatment of mucopolysaccharidosis type IIIA (MPS-IIIA). It consists of a lentiviral vector to insert a functional copy of the human N-Sulfoglucosamine Sulfohydrolase (SGSH) gene into autologous CD34+ hematopoietic stem cells.
Investigational

JTT-251

Investigational
Matched Iupac: … 2-{4-[(9R)-9-hydroxy-2-(3-hydroxy-3-methylbutoxy)-9-(trifluoromethyl)-9H-fluoren-4-yl]-1H-pyrazol-1-yl ... }-2-methylpropanamide …

PYX-201

PYX-201 is an antibody-drug conjugate directed against the extra domain-B splice variant of fibronectin.
Investigational

SIG-205

SIG-205 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral vector to express human native alpha-L-iduronidase enzyme (hIDUA), encapsulated within two-layer modified alginate spheres
Investigational

OTL-203

OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.
Investigational

diethyl [(1R)-1,5-diaminopentyl]boronate

Experimental

2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid

Experimental
Matched Name: … 2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid …
Matched Iupac: … (2R)-2-[(N-hydroxyformamido)methyl]-4-methylpentanoic acid …

5-BROMO-2-{[(4-CHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID

Experimental
Matched Name: … 5-BROMO-2-{[(4-CHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID …
Matched Iupac: … 5-bromo-2-(4-chlorobenzenesulfonamido)benzoic acid …

4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE

Experimental
Matched Name: … 4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE …
Matched Iupac: … 4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benzamide …

3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid

Experimental
Matched Name: … 3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid …
Matched Iupac: … 3-(1,3-benzothiazol-2-ylsulfanyl)propane-1-sulfonic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

1-Monohexanoyl-2-Hydroxy-Sn-Glycero-3-Phosphate

Experimental
Matched Name: … 1-Monohexanoyl-2-Hydroxy-Sn-Glycero-3-Phosphate …
Matched Iupac: … [(2S)-3-(hexanoyloxy)-2-hydroxypropoxy]phosphonic acid …

1-ACETYL-2-LYSO-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Experimental
Matched Name: … 1-ACETYL-2-LYSO-SN-GLYCERO-3-PHOSPHOETHANOLAMINE …
Matched Iupac: … [(2S)-3-(acetyloxy)-2-hydroxypropoxy](2-azaniumylethoxy)phosphinic acid …

VPM4001

VPM4001 is an allogeneic vaccine for treatment of prostate carcinoma. It consists of irradiated human LNCaP cells that have been genetically modified to permanently secrete interferon-γ and interleukin-2 (LNCaP/IL-2/IFN-γ). Interferon-γ enhances presentation of tumour antigens, whereas interleukin-2 stimulates T cells.
Investigational
Matched Description: … (LNCaP/IL-2/IFN-γ). ... Interferon-γ enhances presentation of tumour antigens, whereas interleukin-2 stimulates T cells. ... LNCaP cells that have been genetically modified to permanently secrete interferon-γ and interleukin-2 …

JNJ-40411813

JNJ-40411813 has been used in trials studying the treatment and basic science of Confusion, Schizophrenia, Perceptual Disorders, and Major Depressive Disorder.
Investigational
Matched Iupac: … 1-butyl-3-chloro-4-(4-phenylpiperidin-1-yl)-1,2-dihydropyridin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

JNJ-41443532

JNJ-41443532 has been used in trials studying the basic science and treatment of Diabetes Mellitus, Type 2.
Investigational
Matched Iupac: … N-{1-[(1r,4r)-4-hydroxy-4-(1,3-thiazol-5-yl)cyclohexyl]azetidin-3-yl}-2-{[3-(trifluoromethyl)phenyl]formamido …
Matched Description: … 41443532 has been used in trials studying the basic science and treatment of Diabetes Mellitus, Type 2. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

JNJ-42165279

Jnj-42165279 is under investigation in clinical trial NCT02498392 (An Efficacy, Safety and Tolerability Study of JNJ-42165279 in Participants With Major Depressive Disorder With Anxious Distress).
Investigational
Matched Iupac: … N-(4-chloropyridin-3-yl)-4-[(2,2-difluoro-2H-1,3-benzodioxol-5-yl)methyl]piperazine-1-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Acecainide

Acecainide is an investigational anti-arrhythmia drug.
Investigational
Matched Synonyms: … 4'-((2-(diethylamino)ethyl)carbamoyl)acetanilide ... Benzamide, 4-(acetylamino)-n-(2-(diethylamino)ethyl)- …
Matched Iupac: … N-[2-(diethylamino)ethyl]-4-acetamidobenzamide …

Sulfaethoxypyridazine

Vet approved
Matched Synonyms: … 4-amino-N-(6-ethoxy-3-pyridazinyl)benzenesulfonamide …
Matched Iupac: … 4-amino-N-(6-ethoxypyridazin-3-yl)benzene-1-sulfonamide …

5-Bromo-2'-deoxyuridine 5'-(dihydrogen phosphate)

Experimental
Matched Name: … 5-Bromo-2'-deoxyuridine 5'-(dihydrogen phosphate) …
Matched Iupac: … {[(2R,3S,5R)-5-(5-bromo-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic …

Glycylglutamine

Experimental
Matched Iupac: … (2S)-2-(2-aminoacetamido)-4-carbamoylbutanoic acid …
Displaying drugs 6126 - 6150 of 9061 in total