Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 6201 - 6225 of 8554 in total

Encaleret

Investigational
Matched Synonyms: … (1,1'-biphenyl)-4-carboxylic acid, 2'-((1r)-1-((2r)-3-((2-(4-chloro-3-fluorophenyl)-1,1-dimethylethyl ... (1,1'-biphenyl)-4-carboxylic acid ... -methyl(1,1'-biphenyl)-4-carboxylic acid …
Matched Iupac: … -methyl-[1,1'-biphenyl]-4-carboxylic acid ... 2'-[(1R)-1-[(2R)-3-{[1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl]amino}-2-hydroxypropoxy]ethyl]-3 …

2-Methylpentane-1,2,4-Triol

Experimental

Ligufalimab

Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47. It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Immunoglobulin g4 (225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal ak117 .gamma.4- …

Bunamidine

Bunamidine is a veterinary anti-platyhelmintic agent used for taenia infestations.
Vet approved
Matched Synonyms: … N,N-Dibutyl-4-hexyloxy-1-naphthamidin ... N,N-Dibutyl-4-(hexyloxy)-1-naphthamidine …
Matched Iupac: … N,N-dibutyl-4-(hexyloxy)naphthalene-1-carboximidamide …

LCL-161

LCL161 has been used in trials studying the treatment of Leukemia, Neoplasms, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others.
Investigational
Matched Synonyms: … (2S)-N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl …
Matched Iupac: … (2S)-N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl …

Macelignan

Macelignan is an NSAID with antioxidant, free radical scavenging, and neuroprotective activities.
Experimental
Matched Synonyms: … (8R,8'S)-7-(3,4-methylenedioxyphenyl)-7'-(4-hydroxy-3-methoxyphenyl)-8,8'-dimethylbutane …
Matched Iupac: … 4-[(2S,3R)-4-(2H-1,3-benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol …

Docarpamine

Investigational
Matched Synonyms: … (-)-(s)-2-acetamido-n-(3,4-dihydroxyphenethyl)-4-(methylthio)butyramide bis(ethyl carbonate) (ester) …
Matched Iupac: … 5-{2-[(2S)-2-acetamido-4-(methylsulfanyl)butanamido]ethyl}-2-[(ethoxycarbonyl)oxy]phenyl ethyl carbonate …

(1n)-4-N-Butoxyphenylsulfonyl-(2r)-N-Hydroxycarboxamido-(4s)-Methanesulfonylamino-Pyrrolidine

Experimental
Matched Name: … (1n)-4-N-Butoxyphenylsulfonyl-(2r)-N-Hydroxycarboxamido-(4s)-Methanesulfonylamino-Pyrrolidine …
Matched Iupac: … (2R,4S)-1-(4-butoxybenzenesulfonyl)-N-hydroxy-4-methanesulfonamidopyrrolidine-2-carboxamide …

(R)-Rolipram

The (R)-enantiomer of rolipram, it is a phosphodiesterase inhibitor with antidepressant properties.
Experimental
Matched Synonyms: … (R)-4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolidin-2-one …
Matched Iupac: … (4R)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one …

Olafertinib

Investigational
Matched Synonyms: … N-(3-(2-(2,3-difluoro-4-(4-(2-hydroxyethyl)piperazin-1-yl)phenylamino)quinazolin-8-yl)phenyl)acrylamide …

Rivanicline

Rivanicline (TC-2403, RJR-2403, (E)-metanicotine) is a partial agonist at neuronal nicotinic acetylcholine receptors, binding primarily to the α4β2 subtype. It was originally developed as a potential treatment for Alzheimer's disease for its nootropic effects but has also been found to inhibit the production of Interleukin-8. It has subsequently been developed...
Investigational
Matched Synonyms: … (3E)-N-methyl-4-(pyridin-3-yl)but-3-en-1-amine ... (E)-N-Methyl-4-(3-pyridinyl)-3-butene-1-amine ... N-methyl-4-(3-pyridinyl)-(3E)-3-buten-1-amine …
Matched Iupac: … methyl[(3E)-4-(pyridin-3-yl)but-3-en-1-yl]amine …

4-Fluorophenethyl Alcohol

Experimental
Matched Name: … 4-Fluorophenethyl Alcohol …
Matched Iupac: … 2-(4-fluorophenyl)ethan-1-ol …

TACRINE(8)-4-AMINOQUINOLINE

Experimental
Matched Name: … TACRINE(8)-4-AMINOQUINOLINE …
Matched Iupac: … N1-(quinolin-4-yl)-N8-(1,2,3,4-tetrahydroacridin-9-yl)octane-1,8-diamine …

3-(4-NITRO-PHENOXY)-PROPAN-1-OL

Experimental
Matched Name: … 3-(4-NITRO-PHENOXY)-PROPAN-1-OL …
Matched Iupac: … 3-(4-nitrophenoxy)propan-1-ol …

3(S)-AMINO-4-PHENYL-BUTAN-2(S)-OL

Experimental
Matched Name: … 3(S)-AMINO-4-PHENYL-BUTAN-2(S)-OL …
Matched Iupac: … (2S,3S)-3-amino-4-phenylbutan-2-ol …

2-Nonyl-4-quinolinol 1-oxide

Experimental
Matched Name: … 2-Nonyl-4-quinolinol 1-oxide …
Matched Iupac: … 4-hydroxy-2-nonylquinolin-1-ium-1-olate …

(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine

Experimental
Matched Name: … (3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine …
Matched Iupac: … (2S)-4-methyl-2-{[(3R)-4-(4-methylbenzenesulfonyl)thiomorpholin-3-yl]formamido}pentanoic acid …

(R)-1-(4-(4-(Hydroxymethyl)-1,3,2-dioxaborolan-2-YL)phenethyl)guanidine

Experimental
Matched Name: … (R)-1-(4-(4-(Hydroxymethyl)-1,3,2-dioxaborolan-2-YL)phenethyl)guanidine …
Matched Iupac: … N''-(2-{4-[(4R)-4-(hydroxymethyl)-1,3,2-dioxaborolan-2-yl]phenyl}ethyl)guanidine …

3-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOL

Experimental
Matched Name: … 3-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOL …
Matched Iupac: … 3-[4-amino-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]phenol …

1-[2-HYDROXY-3-(4-CYCLOHEXYL-PHENOXY)-PROPYL]-4-(2-PYRIDYL)-PIPERAZINE

Experimental
Matched Name: … 1-[2-HYDROXY-3-(4-CYCLOHEXYL-PHENOXY)-PROPYL]-4-(2-PYRIDYL)-PIPERAZINE …
Matched Iupac: … (2S)-1-(4-cyclohexylphenoxy)-3-[4-(pyridin-2-yl)piperazin-1-yl]propan-2-ol …

1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Experimental
Matched Name: … 1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine …
Matched Iupac: … 1-tert-butyl-3-[(3-methylphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine …

Ibutamoren

Investigational

Aldosterone

A hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
Experimental
Investigational
Matched Synonyms: … (11β)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al ... 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al ... 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al …

ATG-101

ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, while delivering enhanced anti-tumor activity, with an improved safety profile.
Investigational
Matched Synonyms: … PD-L1/4-1BB bispecific antibody …
Matched Description: … PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, ... ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive …

Quinacrine

An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Investigational
Matched Synonyms: … 3-chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine ... 6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine …
Matched Iupac: … 6-chloro-N-[5-(diethylamino)pentan-2-yl]-2-methoxyacridin-9-amine …
Displaying drugs 6201 - 6225 of 8554 in total