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Displaying drugs 6301 - 6325 of 11673 in total
Experimental
Matched Name: … 3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE …
Matched Iupac: … 3-methoxy-6-[4-(3-methylphenyl)piperazin-1-yl]pyridazine …
Investigational
Fluciclovine is under investigation in clinical trial NCT03036943 (Fluciclovine (18F) Imaging of Breast Cancer).
Investigational
Matched Synonyms: … Anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid ... Cyclobutanecarboxylic acid, 1-amino-3-fluoro-, trans- …
Matched Iupac: … (1r,3r)-1-amino-3-fluorocyclobutane-1-carboxylic acid …
PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface.
Investigational
TNB-383B is a CD3 and B-cell maturation antigen T-cell engaging bispecific antibody.
Investigational
ARO-ANG3 is a subcutaneously administered RNA interference (RNAi)-based investigational medicine targeting angiopoietin-like protein 3 (ANGPTL3). It was granted an orphan drug designation for the treatment of homozygous familial hypercholesterolemia (HoFH).
Investigational
Matched Description: … administered RNA interference (RNAi)-based investigational medicine targeting angiopoietin-like protein 3
VE303 is under clinical development by Vedanta Biosciences.
Investigational
mRNA-3745 is a lipid nanoparticle (LNP) encapsulated with nucleoside-modified, codon-optimized mRNAs encoding human glucose 6-phosphatase (G6Pase).
Investigational
Experimental
Matched Iupac: … (6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one …
Matched Products: … Levo-Methasan 1 mg/ml-Sirup ... L-Polamidon 5 mg Tabletten ... Levo-Methasan 5 mg-Tabletten …
Experimental
Matched Name: … (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE …
Matched Iupac: … (2S)-2-(butanoyloxy)-3-hydroxypropyl nonanoate …
Experimental
Matched Name: … (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid …
Investigational
Matched Synonyms: … N-((3-bromo-4-(3-(fluoro-18f)propoxy)phenyl)methyl)guanidine …
Matched Iupac: … N-({3-bromo-4-[3-(¹⁸F)fluoropropoxy]phenyl}methyl)guanidine …
Experimental
Matched Name: … N-cyclopropyl-N-(trans-4-pyridin-3-ylcyclohexyl)-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide …
Matched Iupac: … N-cyclopropyl-N-[(1r,4r)-4-(pyridin-3-yl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide …
NN344 is a neutral, soluble long-acting human insulin analogue with 24 hour coverage by once daily injection. NN344 has a very flat and predictable action profile. The product is intended for basal insulin treatment of diabetes mellitus.
Investigational
NPI 32101 possesses both anti-inflammatory and broad spectrum antimicrobial activities. This combination of pharmacological properties may have additional therapeutic uses beyond dermatology.
Investigational
C31G is a potent broad spectrum antimicrobial agent, effective against gram positive and gram negative bacteria, yeast and fungi.C31G, vaginal gel is developed by Biosyn Inc. and has commenced enrollment in a phase III pivotal clinical trial for the reduction of sexual transmission of human immunodeficiency virus (HIV).
Investigational
Matched Iupac: … N,N-dimethyldodecanamine oxide 2-(dodecyldimethylazaniumyl)acetate …
ORG-34517 is currently under investigation by Organon for the treatment of depression. It has potential to treat a number of diseases such as Cushing’s disease, hypertension, diabetes, glaucoma etc, in which the activity of metabolites corticosterone and cortisol is high.
Investigational
Matched Iupac: … (1S,3aS,3bS,10R,11aS)-10-(2H-1,3-benzodioxol-5-yl)-1-hydroxy-11a-methyl-1-(prop-1-yn-1-yl)-1H,2H,3H,3aH …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Ly377604 has been used in trials studying the treatment of Obesity.
Investigational
Matched Iupac: … 6-[4-(2-{[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino}-2-methylpropyl)phenoxy]pyridine-3-carboxamide …
LV305 is a lentiviral vector encoding NY-ESO-1 gene. LV305 is an active component of CMB305 along with G305.
Investigational
Matched Description: … LV305 is a lentiviral vector encoding NY-ESO-1 gene. …
mRNA-3927 is an investigational mRNA therapy that consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA carboxylase (PCC) encapsulated within a lipid nanoparticle (LNP). Developed by Moderna Inc., it is being investigated for the treatment of propionic acidemia.
Investigational
Experimental
Matched Name: … [2-Amino-6-(2,6-Difluoro-Benzoyl)-Imidazo[1,2-a]Pyridin-3-Yl]-Phenyl-Methanone …
Matched Iupac: … 3-benzoyl-6-(2,6-difluorobenzoyl)imidazo[1,2-a]pyridin-2-amine …
Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and Efficacy of TAK-079 in Participants With Persistent/chronic Primary Immune Thrombocytopenia).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1-LAMBDA, ANTI-(HOMO SAPIENS ADP-RIBOSYL CYCLASE/CYCLIC ADP-RIBOSE HYDROLASE 1 (2'-PHOSPHO-ADP-RIBOSYL ... CYCLASE, ANTIGENE CD38))HUMANIZED MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN HUMANIZED(1-453) (HOMO SAPIENS ... IMMUNOGLOBULIN G1, ANTI-(HUMAN CD38 ANTIGEN) (HUMAN MONOCLONAL AB79 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN …
Experimental
Matched Name: … 4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole …
Matched Iupac: … 4,5-bis(4-methoxyphenyl)-2-(thiophen-2-yl)-1H-imidazole …
Experimental
Matched Name: … 3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid …
Matched Iupac: … 3-{[(Z)-[(2-methoxyphenyl)methylidene]amino]oxy}propanoic acid …
Experimental
Matched Name: … S-[3-(3,4-DICHLOROPHENYL)-3-OXOPROPYL]-L-CYSTEINE …
Matched Iupac: … (2R)-2-amino-3-{[3-(3,4-dichlorophenyl)-3-oxopropyl]sulfanyl}propanoic acid …
Displaying drugs 6301 - 6325 of 11673 in total