Displaying drugs 6376 - 6400 of 11074 in total
Fosciclopirox
Investigational
Matched Synonyms: … 6-cyclohexyl-4-methyl-1-((phosphonooxy)methoxy)-2(1h)-pyridinone ... 2(1h)-pyridinone, 6-cyclohexyl-4-methyl-1-((phosphonooxy)methoxy)- ... ((6-cyclohexyl-4-methyl-2-oxopyridin-1(2h)-yl)oxy)methyl dihydrogen phosphate …
Apigenin
Experimental
Matched Iupac: … 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Fluciclovine
Fluciclovine is under investigation in clinical trial NCT03036943 (Fluciclovine (18F) Imaging of Breast Cancer).
Investigational
Matched Synonyms: … Anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid ... Cyclobutanecarboxylic acid, 1-amino-3-fluoro-, trans- …
Matched Iupac: … (1r,3r)-1-amino-3-fluorocyclobutane-1-carboxylic acid …
Matched Iupac: … (1r,3r)-1-amino-3-fluorocyclobutane-1-carboxylic acid …
M-(N,N,N-Trimethylammonio)-2,2,2-Trifluoro-1,1-Dihydroxyethylbenzene
Experimental
Matched Iupac: … N,N,N-trimethyl-3-(2,2,2-trifluoro-1,1-dihydroxyethyl)anilinium …
2,6-anhydro-3-deoxy-3-fluoronononic acid
Experimental
Matched Synonyms: … 3-deoxy-3-fluoro-D-erythro-α-L-manno-non-2-ulopyranosonic acid …
Matched Name: … 2,6-anhydro-3-deoxy-3-fluoronononic acid …
Matched Iupac: … (2R,3R,4R,5R,6S)-3-fluoro-2,4,5-trihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
Matched Name: … 2,6-anhydro-3-deoxy-3-fluoronononic acid …
Matched Iupac: … (2R,3R,4R,5R,6S)-3-fluoro-2,4,5-trihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid [4-(Thiazol-2-Ylsulfamoyl)-Phenyl]-Amide
Experimental
Matched Name: … 3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid [4-(Thiazol-2-Ylsulfamoyl)-Phenyl …
Matched Iupac: … 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-{4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}-1-benzofuran-6-sulfonamide …
Matched Iupac: … 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-{4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}-1-benzofuran-6-sulfonamide …
Pipamperone
Pipamperone is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia. It was developed by Janssen Pharmaceutica in 1961 and started its first round of clinical trials in 1963 [L1514, L1518].
In an effort to improve haloperidol's pharmacological effects, Janssen discovered that pipamperone, an agent whose...
Investigational
Matched Iupac: … 1'-[4-(4-fluorophenyl)-4-oxobutyl]-[1,4'-bipiperidine]-4'-carboxamide …
Matched Salts cas: … 2448-68-2 …
Matched Salts cas: … 2448-68-2 …
Elesclomol
Elesclomol is a novel, injectable, drug candidate that kills cancer cells by elevating oxidative stress levels beyond a breaking point, triggering programmed cell death. In preclinical models elesclomol showed potent killing of a broad range of cancer cell types at high doses, and an ability to strongly enhance the efficacy...
Investigational
Matched Synonyms: … 1-N'-Benzenecarbothioyl-3-(2-benzenecarbothioyl-2-methylhydrazinyl)-N'-methyl-oxopropanehydrazidide …
Matched Iupac: … N'1,N'3-dibenzenecarbothioyl-N'1,N'3-dimethylpropanedihydrazide …
Matched Iupac: … N'1,N'3-dibenzenecarbothioyl-N'1,N'3-dimethylpropanedihydrazide …
Phosphopantothenic acid
Experimental
Matched Synonyms: … -alanine, n-((2r)-2-hydroxy-3,3-dimethyl-1-oxo-4-(phosphonooxy)butyl)- …
Matched Iupac: … 3-[(2R)-2-hydroxy-3-methyl-3-[(phosphonooxy)methyl]butanamido]propanoic acid …
Matched Iupac: … 3-[(2R)-2-hydroxy-3-methyl-3-[(phosphonooxy)methyl]butanamido]propanoic acid …
Delta-2-Albomycin A1
Experimental
Matched Name: … Delta-2-Albomycin A1 …
Matched Iupac: … (8S,11R,14R)-14-amino-8-{[(1S)-1-{[(1R,2R)-2-[(2R,3S,4S,5R)-5-[(4Z)-4-(carbamoylimino)-3-methyl-2-oxo ... -1,2,3,4-tetrahydropyrimidin-1-yl]-3,4-dihydroxythiolan-2-yl]-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxyethyl ... ferrapentacyclo[9.9.6.1^{1,4}.1^{1,18}.1^{1,23}]nonacosa-2,19,21-triene-2,20,21-tris(ylium)-1,1,1-triuide ... }-3,19,22-trimethyl-10,13-dioxo-2lambda4,20lambda4,21lambda4,27,28,29-hexaoxa-4,9,12,18,23-pentaaza-1- …
Matched Iupac: … (8S,11R,14R)-14-amino-8-{[(1S)-1-{[(1R,2R)-2-[(2R,3S,4S,5R)-5-[(4Z)-4-(carbamoylimino)-3-methyl-2-oxo ... -1,2,3,4-tetrahydropyrimidin-1-yl]-3,4-dihydroxythiolan-2-yl]-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxyethyl ... ferrapentacyclo[9.9.6.1^{1,4}.1^{1,18}.1^{1,23}]nonacosa-2,19,21-triene-2,20,21-tris(ylium)-1,1,1-triuide ... }-3,19,22-trimethyl-10,13-dioxo-2lambda4,20lambda4,21lambda4,27,28,29-hexaoxa-4,9,12,18,23-pentaaza-1- …
{1-[2-(1-FORMYL-PROPYL)-3-METHANESULFONYLAMINO-PYRROLIDINE-1-CARBONYL]-2-METHYL-PROPYL}-CARBAMIC ACID TERT-BUTYL ESTER
Experimental
Matched Name: … {1-[2-(1-FORMYL-PROPYL)-3-METHANESULFONYLAMINO-PYRROLIDINE-1-CARBONYL]-2-METHYL-PROPYL}-CARBAMIC ACID …
Matched Iupac: … tert-butyl N-[(2S)-1-[(2R,3S)-3-methanesulfonamido-2-[(2S)-1-oxobutan-2-yl]pyrrolidin-1-yl]-3-methyl- ... 1-oxobutan-2-yl]carbamate …
Matched Iupac: … tert-butyl N-[(2S)-1-[(2R,3S)-3-methanesulfonamido-2-[(2S)-1-oxobutan-2-yl]pyrrolidin-1-yl]-3-methyl- ... 1-oxobutan-2-yl]carbamate …
MUC1 Dendritic Cell Vaccine
Dendritic Cell (DC) Therapy is a newly emerging and potent form of immune therapy that amplifies the actions of the body's own immune system to help fight cancer, AIDS and other serious conditions. The Dendritic Cell is an immune cell whose role is the recognition, processing and presentation of foreign...
Investigational
Exbivirumab
Exbivirumab is an investigational monoclonal antibody. It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.
Investigational
Modakafusp alfa
Modakafusp alfa is under investigation in clinical trial NCT03215030 (A Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of TAK-573 in Participants With Refractory Multiple Myeloma (MM)).
Investigational
Beludavimab
Beludavimab is under investigation in clinical trial NCT04746183 (AGILE (Early Phase Platform Trial for COVID-19)).
Investigational
Matched Synonyms: … LEUCINE,342-GLUTAMIC ACID,438-LEUCINE,444-SERINE), ANTI-(SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 ... SPIKE GLYCOPROTEIN RECEPTOR-BINDING DOMAIN) (HUMAN MONOCLONAL VIR-7832 .GAMMA.1-CHAIN), DISULFIDE WITH …
Mepiprazole
Mepiprazole is a minor tranquilizer with a phenylpiperazine structure. It is a pyrazolyl-alkyl-piperazine derivative. Mepiprazole mediates a weak inhibitory action on the uptake of 5-HT on hypothalamic neurons .
Mepiprazole is marketed in Spain for the treatment of anxiety neuroses.
It acts as a 5-HT2A and α1-adrenergic receptor antagonist, and...
Experimental
Matched Iupac: … 1-(3-chlorophenyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethyl]piperazine …
Matched Description: … Mepiprazole mediates a weak inhibitory action on the uptake of 5-HT on hypothalamic neurons [A7816]. ... It acts as a 5-HT2A and α1-adrenergic receptor antagonist, and has also been shown to inhibit the reuptake …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Mepiprazole mediates a weak inhibitory action on the uptake of 5-HT on hypothalamic neurons [A7816]. ... It acts as a 5-HT2A and α1-adrenergic receptor antagonist, and has also been shown to inhibit the reuptake …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
USL-311
USL-311 is under investigation in clinical trial NCT02765165 (Phase 1/2 Study of USL311 Alone and in Combination With Lomustine in Subjects With Advanced Solid Tumors and Relapsed/Recurrent Glioblastoma Multiforme (GBM)).
Investigational
Matched Synonyms: … 6-[4-(1-propan-2-ylpiperidin-4-yl)-1,4-diazepan-1-yl]-N-pyridin-4-ylpyridine-2-carboxamide ... 2-Pyridinecarboxamide, 6-(hexahydro-4-(1-(1-methylethyl)-4-piperidinyl)-1H-1,4-diazepin-1-yl)-N-4-pyridinyl ... 6-{4-[l-(propan-2-yl)piperidin-4-yl]-1,4-diazepan-1-yl}-N-(pyridin-4-yl)pyridine-2-carboxamide …
Matched Iupac: … 6-{4-[1-(propan-2-yl)piperidin-4-yl]-1,4-diazepan-1-yl}-N-(pyridin-4-yl)pyridine-2-carboxamide …
Matched Description: … USL-311 is under investigation in clinical trial NCT02765165 (Phase 1/2 Study of USL311 Alone and in …
Matched Iupac: … 6-{4-[1-(propan-2-yl)piperidin-4-yl]-1,4-diazepan-1-yl}-N-(pyridin-4-yl)pyridine-2-carboxamide …
Matched Description: … USL-311 is under investigation in clinical trial NCT02765165 (Phase 1/2 Study of USL311 Alone and in …
2-Methoxyestradiol
2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis). It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis.
Investigational
Matched Synonyms: … 2-Hydroxyestradiol 2-methyl ether ... 2-Hydroxyestradol 2-methyl ether ... 2-ME2 …
Matched Name: … 2-Methoxyestradiol …
Matched Description: … 2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need ... It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that …
Matched Name: … 2-Methoxyestradiol …
Matched Description: … 2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need ... It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that …
Icaritin
Icaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC).
Investigational
Matched Iupac: … 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Licofelone
Developed by the German pharmaceutical company, Merckle GmbH, together with EuroAlliance partners Alfa Wassermann and Lacer, licofelone (ML3000) is a dual COX/LOX inhibitor and the first member of this new class of analgesic and anti-inflammatory drugs. It is currently under evaluation as a treatment for osteoarthritis (OA), the most common...
Investigational
Matched Iupac: … 2-[6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl]acetic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
1,2-Dihydroxybenzene
Experimental
3-Fluoro-2-Methyl-Aniline
Experimental
Matched Name: … 3-Fluoro-2-Methyl-Aniline …
Matched Iupac: … 3-fluoro-2-methylaniline …
Matched Iupac: … 3-fluoro-2-methylaniline …
(4Z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]amino}methylidene)isoquinoline-1,3(2H,4H)-dione
Experimental
Matched Name: … (4Z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]amino}methylidene)isoquinoline-1,3(2H,4H)-dione …
Matched Iupac: … (4Z)-6-bromo-4-[({4-[(pyrrolidin-1-yl)methyl]phenyl}amino)methylidene]-1,2,3,4-tetrahydroisoquinoline …
Matched Iupac: … (4Z)-6-bromo-4-[({4-[(pyrrolidin-1-yl)methyl]phenyl}amino)methylidene]-1,2,3,4-tetrahydroisoquinoline …
Displaying drugs 6376 - 6400 of 11074 in total