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Displaying drugs 6426 - 6450 of 10203 in total
Thymalfasin is a chemically synthesized version of thymosin alpha 1 that is identical to human thymosin alpha 1. Thymosin alpha 1 is an acetylated polypeptide. Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. It is also used to boost the...
Investigational
Experimental
Matched Name: … 1-[(2-Amino-6,9-Dihydro-1h-Purin-6-Yl)Oxy]-3-Methyl-2-Butanol …
Matched Iupac: … 1-[(2-amino-7H-purin-6-yl)oxy]-3-methylbutan-2-one …
ND7001, a selective PDE2 inhibitor is in clinical trials for the treatment of depression. ND7001 is a solid. Known drug targets of ND7001 including phosphodiesterase 2A, cGMP-stimulated and cGMP-dependent 3',5'-cyclic phosphodiesterase. It is a new type of antidepressant drug with anxiolytic activity. It is the first representative of a new...
Investigational
Matched Description: … Known drug targets of ND7001 including phosphodiesterase 2A, cGMP-stimulated and cGMP-dependent 3',5' …
Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. Its pharmacological activity thus confers the risk for hypokalemia.
Withdrawn
Matched Synonyms: … 6-Ethoxy-1,3-benzothiazole-2-sulfonamide …
Matched Iupac: … 6-ethoxy-1,3-benzothiazole-2-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
A 17-alkylated orally active androgenic steroid. A Schedule IV drug in Canada.
Experimental
Illicit
Matched Synonyms: … 17beta-Hydroxy-7beta,17-dimethylandrost-4-en-3-one ... 17-beta-Hydroxy-7-beta,17-alpha-dimethylandrost-4-ene-3-one ... 17beta-Hydroxy-7beta,17alpha-dimethylandrost-4-ene-3-one …
Investigational
Matched Synonyms: … g1-kappa, cell-penetrating humanized fab fragment targeting the equilibrative nucleoside transporter 2
A phosphodiesterase inhibitor with antidepressant properties.
Investigational
Matched Synonyms: … 4-(3-(Cyclopentyloxy)-4-methoxyphenyl)-2-pyrrolidinone …
Matched Iupac: … 4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one …
Experimental
Matched Name: … Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl …
Matched Iupac: … 2-{4-[(4S,5R)-4,5-bis(4-bromophenyl)-2-(2-ethoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl …
Investigational
Experimental
Matched Name: … [2-Amino-6-(2,6-Difluoro-Benzoyl)-Imidazo[1,2-a]Pyridin-3-Yl]-Phenyl-Methanone …
Matched Iupac: … 3-benzoyl-6-(2,6-difluorobenzoyl)imidazo[1,2-a]pyridin-2-amine …
Experimental
Matched Name: … 2-(1H-pyrazol-3-yl)-1H-benzimidazole …
Matched Iupac: … 2-(1H-pyrazol-3-yl)-1H-1,3-benzodiazole …
Experimental
Matched Name: … N-(3-AMINOPROPYL)-2-NITROBENZENAMINE …
Matched Iupac: … N1-(2-nitrophenyl)propane-1,3-diamine …
Experimental
Matched Name: … 4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile …
Matched Iupac: … 4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile …
VLTS-589 consists of plasmid encoding the angiomatrix protein Del-1 in conjunction with poloxamer 188 for the treatment of peripheral vascular disease.
Investigational
NP-50301 is an ophthalmic therapeutic eye drop treating post-menopausal Dry Eye Syndrome (DES). It is being developed by Nascent Pharmaceuticals. It is estimated that about 30% of postmenopausal women suffer symptoms of DES, which accounts for over 12 million women in the U.S. The majority of sufferers of DES are...
Investigational
SNX-5422 is a synthetic, novel, small molecule Hsp90 Inhibitor. As an oral formulation that demonstrates strong efficacy and tolerability, SNX-5422 is positioned as a breakthrough therapy with broad applicability across a wide range of cancers.
Investigational
Matched Iupac: … (1r,4r)-4-({2-carbamoyl-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl] ... phenyl}amino)cyclohexyl 2-aminoacetate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
KRN-5500 is under investigation in clinical trial NCT00002923 (KRN5500 in Treating Patients With Metastatic Solid Tumors).
Investigational
Matched Iupac: … 3-yl]carbamoyl}methyl)tetradeca-2,4-dienamide ... (2E,4E)-N-({[(2R,3R,4R,5R,6S)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxy-6-[(9H-purin-6-yl)amino]oxan- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
The V590 vaccine was developed on Merck’s recombinant vesicular stomatitis virus (rVSV) platform that was previously used to develop its Ebola Zaire virus vaccine, ERVEBO®[A226818, L30573, L30578]. By teaming up with IAVI, Merk developed a vaccine that does not require freezing, and only requires one dose . Other features of...
Investigational
Investigational
Matched Iupac: … N-(2-{[(2,3-difluorophenyl)methyl]sulfanyl}-6-{[(2R,3S)-3,4-dihydroxybutan-2-yl]oxy}pyrimidin-4-yl)azetidine …
KITE-585 is an autologous, fully-human anti-B cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cell therapy. It is being investigated in the treatment of multiple myeloma.
Investigational
ABBV-514 is in development for the treatment of non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) as a single agent and in combination with a PD-1 inhibitor.
Investigational
Experimental
Matched Name: … 4,6-Dideoxy-4-{[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino}hexopyranose …
Matched Iupac: … (2R,3R,4S,5S,6R)-6-methyl-5-{[(1S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}oxane …
Experimental
Matched Name: … S-(2-oxo)pentadecylcoa …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3S)-3-hydroxy-2,2-dimethyl ... -3-{[2-({2-[(2-oxopentadecyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propoxy]phosphoryl}oxy)phosphoryl ... ]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid …
Experimental
Matched Iupac: … 3-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl ... ]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido …
Displaying drugs 6426 - 6450 of 10203 in total