Rolipram

DB01954InvestigationalSmall molecule

A phosphodiesterase inhibitor with antidepressant properties.

Chemical structure of Rolipram
Mechanism
Curator reviewed
Formula / weight
C16H21NO3 · 275.348 g/mol (avg)
Code names
BRN 1588548 · SB-95952 · ZK-62711 · ZK-62771

Resolves to

Compound
UNIIK676NL63N7CAS61413-54-5ChEMBLCHEMBL63ChEBI104872PubChem5092KEGGD01783
Clinical / RWD
PharmGKBPA153906323
Structure
InChIKeyHJORMJIFDVBMOB-UHFFFAOYSA-NSMILESCOC1=C(OC2CCCC2)C=C(C=C1)C1CNC(=O)C1
Targets
Q07343PDE4BQ08499PDE4DP27815PDE4AO76074PDE5A

What you can answer from here — as of September 23, 2026

6Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
681Drug interactionsStructured to mechanism, not free text
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4Clinical trialsPhase, status and sponsor resolved per trial
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9+ReferencesStructured and connected to the statements they support
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