Displaying drugs 626 - 650 of 1015 in total
Pregnenolone acetate
Investigational
Matched Synonyms: … 3beta-Hydroxypregn-5-en-20-one acetate …
Matched Name: … Pregnenolone acetate …
Matched Iupac: … -9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl acetate …
Matched Name: … Pregnenolone acetate …
Matched Iupac: … -9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl acetate …
Fluprednidene acetate
Fluprednidene acetate is a corticosteroid. It has anti-inflammatory and anti-allergic properties.
Experimental
Matched Name: … Fluprednidene acetate …
Matched Iupac: … methylidene-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate …
Matched Description: … Fluprednidene acetate is a corticosteroid. It has anti-inflammatory and anti-allergic properties. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … methylidene-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate …
Matched Description: … Fluprednidene acetate is a corticosteroid. It has anti-inflammatory and anti-allergic properties. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Dibenzyl (carbonylbis{2,1-hydrazinediyl[(2S)-4-methyl-1-oxo-1,2-pentanediyl]})biscarbamate
Experimental
Matched Synonyms: … 1,5-Bis(N-benzyloxycarbonyl-L-leucinyl)carbohydrazide …
Levodopa
Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label]. Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent...
Approved
Matched Synonyms: … Dihydroxy-L-phenylalanine ... 3,4-Dihydroxy-L-phenylalanine …
Matched Description: … Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally ... Once past the blood-brain barrier, levodopa is metabolized to dopamine and supplements the low endogenous ... The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product …
Matched Mixtures name: … Carbidopa and Levodopa ... Carbidopa and Levodopa ... Carbidopa and Levodopa …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Dopa and Dopa Derivatives ... levodopa and decarboxylase inhibitor ... levodopa, decarboxylase inhibitor and COMT inhibitor …
Matched Description: … Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally ... Once past the blood-brain barrier, levodopa is metabolized to dopamine and supplements the low endogenous ... The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product …
Matched Mixtures name: … Carbidopa and Levodopa ... Carbidopa and Levodopa ... Carbidopa and Levodopa …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Dopa and Dopa Derivatives ... levodopa and decarboxylase inhibitor ... levodopa, decarboxylase inhibitor and COMT inhibitor …
Acetylcysteine
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168]
Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Synonyms: … N-acetyl-L-cysteine ... N-acetyl-L-(+)-cysteine …
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Cysteine …
Matched Products: … Acetadote …
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Cysteine …
Matched Products: … Acetadote …
5'-O-(L-Cysteinylsulfamoyl)adenosine
Experimental
Matched Synonyms: … 5'-O-(N-(L-Cysteinyl)-sulfamoyl)adenosine …
4-[(Isopropylamino)Methyl]Phenylalanine
Experimental
Matched Name: … 4-[(Isopropylamino)Methyl]Phenylalanine …
Loncastuximab tesirine
Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through A protease cleavable valine-alanine …
Matched Description: … and improve survival. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... [A234439] Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Description: … and improve survival. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... [A234439] Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
N-(biphenyl-4-ylsulfonyl)-D-leucine
Experimental
Matched Name: … N-(biphenyl-4-ylsulfonyl)-D-leucine …
Zoledronate D,L-Lysine Monohydrate
Approved
Investigational
Matched Name: … Zoledronate D,L-Lysine Monohydrate …
L-cysteic acid
L-cysteic acid is a beta-sulfoalanine. It is an amino acid with a C-terminal sulfonic acid group which has been isolated from human hair oxidized with permanganate. It occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light and weather.
Experimental
Matched Synonyms: … L-Cysteate …
Matched Name: … L-cysteic acid …
Matched Description: … It occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light and weather ... L-cysteic acid is a beta-sulfoalanine. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … L-cysteic acid …
Matched Description: … It occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light and weather ... L-cysteic acid is a beta-sulfoalanine. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Caspofungin
Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal...
Approved
Matched Description: … It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan ... Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug …
Matched Salts name: … Caspofungin acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Caspofungin Acetate ... Caspofungin acetate ... Caspofungin Acetate for Injection …
Matched Salts name: … Caspofungin acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Caspofungin Acetate ... Caspofungin acetate ... Caspofungin Acetate for Injection …
Josamycin
A macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
Investigational
Matched Synonyms: … leucomycin V 3-acetate 4B-(3-methylbutanoate) ... leucomycin V 3-acetate 4β-(3-methylbutanoate) …
Matched Categories: … Macrolides, Lincosamides and Streptogramins …
Matched Categories: … Macrolides, Lincosamides and Streptogramins …
Thermus thermophilus lysate
Experimental
Matched Synonyms: … Thermus thermophilus lysate …
Matched Name: … Thermus thermophilus lysate …
Matched Name: … Thermus thermophilus lysate …
Methyl (2S)-2-[[2-[(3R)-1-carbamimidoylpiperidin-3-yl]acetyl]amino]-3-[4-(2-phenylethynyl)phenyl]propanoate
This solid compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. This substance targets the protein interleukin-2.
Experimental
Matched Synonyms: … Methyl N-{[(3R)-1-carbamimidoyl-3-piperidinyl]acetyl}-4-(phenylethynyl)-L-phenylalaninate …
DADLE
A delta-selective opioid (ANALGESICS, OPIOID). It can cause transient depression of mean arterial blood pressure and heart rate.
Experimental
Matched Synonyms: … L-Tyrosyl-D-alanylglycyl-L-phenylalanyl-D-leucine …
Matched Description: … It can cause transient depression of mean arterial blood pressure and heart rate. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enkephalin, Leucine …
Matched Description: … It can cause transient depression of mean arterial blood pressure and heart rate. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enkephalin, Leucine …
Irinotecan
Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Description: … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] ... irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and …
Matched Salts name: … Irinotecan hydrochloride ... Irinotecan hydrochloride hydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Irinotecan Hydrochloride ... Irinotecan hydrochloride ... Irinotecan hydrochloide …
Matched Salts name: … Irinotecan hydrochloride ... Irinotecan hydrochloride hydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Irinotecan Hydrochloride ... Irinotecan hydrochloride ... Irinotecan hydrochloide …
Displaying drugs 626 - 650 of 1015 in total