Displaying drugs 626 - 650 of 800 in total
Volociximab
Investigational
Matched Synonyms: … Anti-alpha5beta1 integrin monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bemarituzumab
Bemarituzumab is under investigation in clinical trial NCT03694522 (A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (Mfolfox6) in Gastric/gastroesophageal Junction Cancer (FIGHT)).
Investigational
Matched Synonyms: … Anti-fgfr2 monoclonal antibody fpa144 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
ATG-101
ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, while delivering enhanced anti-tumor activity, with an improved safety profile.
Investigational
Matched Synonyms: … PD-L1/4-1BB bispecific antibody …
Matched Description: … PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, ... ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive …
Matched Description: … PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, ... ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive …
Ethyl Oxo(Piperidin-1-Yl)Acetate
Experimental
Matched Name: … Ethyl Oxo(Piperidin-1-Yl)Acetate …
Matched Iupac: … ethyl 2-oxo-2-(piperidin-1-yl)acetate …
Matched Iupac: … ethyl 2-oxo-2-(piperidin-1-yl)acetate …
Mavodelpar
Investigational
Matched Synonyms: … (4-{(E)-3-(4-fluorophenyl)-3-[4-(3-morpholin-4-yl-prop-1ynyl)phenyl]allyloxy}-2-methylphenoxy)acetate …
Elm
Elm is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Ulmus Rubra Inner Bark …
Axatilimab
Axatilimab is under investigation in clinical trial NCT04301778 (Durvalumab in Combination With a CSF-1R Inhibitor (SNDX-6532) Following Chemo or Radio-embolization for Patients With Intrahepatic Cholangiocarcinoma).
Investigational
Matched Synonyms: … anti-Csf1R monoclonal antibody SNDX-6352 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
XMMME-001-DTPA 111 Indium
Investigational
Matched Synonyms: … Antimelanoma antibody XMMME-001-DTPA 111 Indium …
MDX-210
Investigational
Matched Synonyms: … Bispecific antibody 520c9x22 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Glofitamab
Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- and T-cells, respectively. It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting T-cells directly to the surface of cancerous B-cells.[L45698,A258488]
Glofitamab was approved...
Approved
Investigational
Matched Synonyms: … Anti-CD20/CD3 bispecific monoclonal antibody RO7082859 …
Matched Description: … Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface ... It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting ... antigens found on B- and T-cells, respectively. …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface ... It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting ... antigens found on B- and T-cells, respectively. …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
SEA-BCMA
Investigational
Matched Synonyms: … Anti-bcma antibody sea-bcma ... Nonfucosylated humanized immunoglobulin G1 (IgG1) monoclonal antibody targeting B-cell maturation antigen …
STX-100
STX-100 is under investigation in clinical trial NCT01371305 (STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).
Investigational
Matched Synonyms: … Humanized monoclonal antibody against human integrin alphaVbeta6 …
XMMME-001-RTA
Investigational
Matched Synonyms: … Antimelanoma antibody XMMME-001-RTA …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
TCN-202
Investigational
Matched Synonyms: … TCN-202 (human anti-cytomegalovirus monoclonal antibody) …
CN-201
CN-201 is a humanized anti-CD3/CD19 bispecific antibody.
Investigational
Matched Synonyms: … recombinant humanized anti-CD3/CD19 bispecific antibody …
Matched Description: … CN-201 is a humanized anti-CD3/CD19 bispecific antibody. …
Matched Description: … CN-201 is a humanized anti-CD3/CD19 bispecific antibody. …
HH-009
HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment of hepatocellular carcinoma.
Investigational
Matched Synonyms: … recombinant human IgG4 monoclonal antibody against FGF19 …
Matched Description: … HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment …
Matched Description: … HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment …
Cefuroxime
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Panobacumab
Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA-101 in Hospital Acquired Pneumonia Caused by O11 Pseudomonas Aeruginosa).
Investigational
Matched Synonyms: … Human monoclonal antibody directed against serotype 011 Pseudomonas aeruginosa ... Human monoclonal antibody directed against serotype O1 Pseudomonas aeruginosa …
Matched Description: … Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA …
Matched Description: … Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA …
Girentuximab
Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, an antigen expressed in 95% of clear cell renal cell carcinomas (RCC).
Investigational
Matched Synonyms: … Chimeric (human-murine) G250 IgG monoclonal antibody …
Matched Description: … Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, …
Matched Categories: … Amino Acids, Peptides, and Proteins …
LJP-538
Investigational
Matched Synonyms: … Human IgG1 anti-human cytomegalovirus monoclonal antibody LJP538 …
Rocatinlimab
Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe atopic dermatitis. In clinical trials, it has shown significant efficacy and safety compared to a placebo. The drug works by targeting the OX40 receptor, which plays a role in the immune response associated with atopic dermatitis. Despite...
Investigational
Matched Synonyms: … Anti-CD134 human monoclonal antibody (IgG1, KHK4083 dimer) …
Matched Description: … injection reactions such as fever and chills have been reported. ... In clinical trials, it has shown significant efficacy and safety compared to a placebo. ... Additionally, the diverse genetic backgrounds of patients may influence the drug’s effectiveness and …
Matched Description: … injection reactions such as fever and chills have been reported. ... In clinical trials, it has shown significant efficacy and safety compared to a placebo. ... Additionally, the diverse genetic backgrounds of patients may influence the drug’s effectiveness and …
Ximelagatran
Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue...
Approved
Investigational
Withdrawn
Matched Synonyms: … cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin-1-yl]- 2-oxo-ethyl]amino]acetate …
Matched Iupac: … 2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin-1-yl]-2-oxoethyl]amino}acetate …
Matched Description: … intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and ... would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and …
Matched Categories: … Blood and Blood Forming Organs …
Matched Iupac: … 2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin-1-yl]-2-oxoethyl]amino}acetate …
Matched Description: … intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and ... would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and …
Matched Categories: … Blood and Blood Forming Organs …
Displaying drugs 626 - 650 of 800 in total