Displaying drugs 6526 - 6550 of 7689 in total
MB-07803
MB07803 is a second generation gluconeogenesis inhibitor for the treatment of type 2 diabetes. It is designed to block the metabolic pathway in the liver that is responsible for producing glucose.
Investigational
Matched Iupac: … ethyl 2-[({5-[2-amino-5-(2,2-dimethylpropanoyl)-1,3-thiazol-4-yl]furan-2-yl}[(1-ethoxy-2-methyl-1-oxopropan …
Managlinat dialanetil
CS-917 is a novel inhibitor of fructose 1,6-bisphphosphatase (FBPase) which is one of the rate-limiting enzymes of gluconeogenesis.
Investigational
Matched Iupac: … ethyl (2S)-2-[({5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl}({[(2S)-1-ethoxy-1-oxopropan …
GLPG-0259
GLPG-0259 is under investigation in clinical trial NCT01024517 (GLPG0259 Solid Formulation Bioavailability and Food Effect).
Investigational
Matched Iupac: … -a]pyrazin-5-yl]furan-2-carboxamide ... 4-[8-({4-[(1S,4S)-5-(propan-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl}amino)-[1,2,4]triazolo[1,5 …
Olinciguat
Olinciguat is under investigation in clinical trial NCT03892499 (A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator, Olinciguat (IW-1701), in Healthy Volunteers).
Investigational
Matched Iupac: … (2R)-3-[(5-fluoro-2-{1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)-1H-pyrazol-3-yl}pyrimidin-4-yl)amino …
Narasin
Narasin is an agent with coccidiostatic and antibacterial properties.
Experimental
Vet approved
Matched Iupac: … (2R)-2-[(2R,3S,5S,6R)-6-[(2S,3S,4S,6R)-6-[(2S,5S,7R,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-ethyl-5-hydroxy-6 ... ]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-3,5-dimethyloxan-2-yl]butanoic acid ... -methyloxan-2-yl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5^{7}.3^{5}]pentadec-13-en-9-yl …
Brivanib alaninate
Brivanib alaninate has been investigated for the treatment of Colorectal Cancer.
Investigational
Matched Iupac: … (2R)-1-({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)propan …
AZD-8165
AZD-8165 is under investigation in clinical trial NCT01150812 (Oral AZD8165 After Single Oral Ascending Doses in Healthy Male Subjects).
Investigational
Matched Iupac: … (1R)-2-[(5S)-5-({[5-chloro-2-(1H-1,2,3,4-tetrazol-1-yl)phenyl]methyl}carbamoyl)-4,5-dihydro-1H-pyrazol …
11-Deoxy-Beta-Rhodomycin
Experimental
Matched Iupac: … (7R,8R,10S)-10-{[(2R,4S,5S,6S)-4-(dimethylamino)-5-{[(2S,4S,5R,6S)-4-hydroxy-6-methyl-5-{[(2R,6R)-6-methyl ... -5-oxooxan-2-yl]oxy}oxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-8-ethyl-1,7,8,11-tetrahydroxy-5,7,8,9,10,12 …
10-decarboxymethylaclacinomycin A
Experimental
Matched Iupac: … (8S,10S)-10-{[(2R,4S,5S,6S)-4-(dimethylamino)-5-{[(2R,4S,5R,6S)-4-hydroxy-6-methyl-5-{[(2R,6R)-6-methyl ... -5-oxooxan-2-yl]oxy}oxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-8-ethyl-1,8,11-trihydroxy-5,7,8,9,10,12-hexahydrotetracene …
(2s,3s)-Trans-2,3-Dihydro-3-Hydroxyanthranilic Acid
Experimental
Matched Iupac: … (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic acid …
N(2)-succinyl-L-arginine
Experimental
Matched Iupac: … (2S)-5-carbamimidamido-2-[(3-carboxy-1-hydroxypropylidene)amino]pentanoic acid …
Ndelta-(N'-Sulphodiaminophosphinyl)-L-Ornithine
Experimental
Matched Iupac: … (2S)-2-amino-5-{[(R)-amino(sulfoamino)phosphoryl]amino}pentanoic acid …
Piritrexim
Piritrexim has been used in trials studying the treatment of Bladder Cancer, Urethral Cancer, and Transitional Cell Cancer of the Renal Pelvis and Ureter.
Investigational
Matched Iupac: … 6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine …
Matched Salts cas: … 79483-69-5 …
Matched Salts cas: … 79483-69-5 …
Carboxymethylthio-3-(3-Chlorophenyl)-1,2,4-Oxadiazol
Experimental
Matched Iupac: … 2-{[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]sulfanyl}acetic acid …
Prinaberel
Prinaberel is an estrogen receptor beta agonist.
Investigational
Matched Iupac: … 7-ethenyl-2-(3-fluoro-4-hydroxyphenyl)-1,3-benzoxazol-5-ol …
R-95845
R-95845 is an inhibitor of HIV-1 reverse transcriptase.
Experimental
Matched Iupac: … (2S)-2-[(2-acetyl-5-methylphenyl)amino]-2-(2,6-dibromophenyl)acetamide …
METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATE
Experimental
Matched Iupac: … 2-[(1R)-1-(acetyloxy)-2-methoxy-2-oxoethyl]-5-aminobenzoic acid …
Ciglitazone
Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class.
Ciglitazone was never used as a medication, but it sparked interest in the effects of thiazolidinediones. Several analogues were later developed, some of which—such as pioglitazone and troglitazone—made it to the market....
Experimental
Matched Iupac: … 5-({4-[(1-methylcyclohexyl)methoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione …
LY-295501
ILX-295501 has been used in trials studying the treatment of Ovarian Cancer, Metastatic Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cavity Cancer.
Investigational
Matched Iupac: … 1-(3,4-dichlorophenyl)-3-(2,3-dihydro-1-benzofuran-5-sulfonyl)urea …
BK-MDA
BK-MDA has been used in trials studying the treatment of Bladder Exstrophy and Urinary Incontinence.
Investigational
Matched Iupac: … 2-amino-1-(2H-1,3-benzodioxol-5-yl)propan-1-one …
123I-iodometomidate
123I-iodometomidate is under investigation in clinical trial NCT00454103 (Evaluation of 123I-Iodometomidate for Adrenal Scintigraphy).
Investigational
Matched Iupac: … methyl 1-[(1R)-1-(4-iodophenyl)ethyl]-1H-imidazole-5-carboxylate …
Flunoxaprofen
Experimental
Matched Iupac: … (2S)-2-[2-(4-fluorophenyl)-1,3-benzoxazol-5-yl]propanoic acid …
Aspartyl-alanyl-diketopiperazine
Aspartyl-alanyl-diketopiperazine is under investigation in clinical trial NCT03349645 (An Open Label Extension Study to Assess the Safety of Long-Term Treatment With Ampion for Severe OA of the Knee).
Investigational
Matched Iupac: … 2-[(2S,5S)-5-methyl-3,6-dioxopiperazin-2-yl]acetic acid …
Displaying drugs 6526 - 6550 of 7689 in total