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Displaying drugs 6901 - 6925 of 12112 in total

Pegilodecakin

Pegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).
Investigational
Matched Synonyms: … INTERLEUKIN 10 (SYNTHETIC HUMAN), DIMER, N-TERMINAL 5-KILODALTON PEGYLATED …

Mubodina

Mubodina is an investigational drug developed by Adienne Pharma & Biotech. It is a recombinant human minibody directed against complement component C5. It was investigated in various conditions including primary membranoproliferative glomerulonephritis and typical hemolytic uremic syndrome.
Investigational

Larsucosterol

Investigational
Matched Synonyms: … 5-cholesten-3.beta.-25-diol-3-sulfate ... 5-cholesten-3.beta., 25-diol 3-sulfate ... 25-hydroxycholest-5-en-3.beta.-yl hydrogen sulfate …
Matched Iupac: … [(1R,3aS,3bS,7S,9aR,9bS,11aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-9a,11a-dimethyl-1H,2H,3H,3aH,3bH …
Matched Salts cas: … 1174047-40-5 …

4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine

Experimental
Matched Name: … 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine …
Matched Iupac: … 4-(2,5-dichlorothiophen-3-yl)pyrimidin-2-amine …

2s,4r-4-Methylglutamate

Experimental
Matched Name: … 2s,4r-4-Methylglutamate …
Matched Iupac: … (2R,4S)-4-amino-4-carboxy-2-methylbutanoate …

Naringenin

Experimental
Matched Iupac: … (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Diundecyl Phosphatidyl Choline

Experimental

2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine

Experimental

4-S-Glutathionyl-5-pentyl-tetrahydro-furan-2-ol

Experimental
Matched Name: … 4-S-Glutathionyl-5-pentyl-tetrahydro-furan-2-ol …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(2R,3S,5R)-5-hydroxy-2-pentyloxolan-3-yl]sulfanyl …

2-((3',5'-DIMETHYL-4'-HYDROXYPHENYL)AZO)BENZOIC ACID

Experimental
Matched Name: … 2-((3',5'-DIMETHYL-4'-HYDROXYPHENYL)AZO)BENZOIC ACID …
Matched Iupac: … 2-[(1E)-2-(4-hydroxy-3,5-dimethylphenyl)diazen-1-yl]benzoic acid …

Verubulin

Antineoplastic; a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps.
Investigational
Matched Iupac: … N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine …
Matched Salts cas: … 917369-31-4 …

p-Aminophenol

Experimental
Matched Synonyms: … 4-Aminophenol ... 4-Aminobenzenol ... 4-Hydroxyaniline …
Matched Iupac: … 4-aminophenol …
Matched Salts cas: … 51-78-5 …

N-[4-hydroxymethyl-cyclohexan-6-yl-1,2,3-triol]-4,6-dideoxy-4-aminoglucopyranoside

Experimental
Matched Name: … N-[4-hydroxymethyl-cyclohexan-6-yl-1,2,3-triol]-4,6-dideoxy-4-aminoglucopyranoside …
Matched Iupac: … (2S,3R,4S,5S,6R)-6-methyl-5-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino …

9-(5,5-Difluoro-5-Phosphonopentyl)Guanine

Experimental
Matched Name: … 9-(5,5-Difluoro-5-Phosphonopentyl)Guanine …
Matched Iupac: … [5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-1,1-difluoropentyl]phosphonic acid …

(2E)-3-{3-[(5-ETHYL-3-IODO-6-METHYL-2-OXO-1,2-DIHYDROPYRIDIN-4-YL)OXY]PHENYL}ACRYLONITRILE

Experimental
Matched Name: … (2E)-3-{3-[(5-ETHYL-3-IODO-6-METHYL-2-OXO-1,2-DIHYDROPYRIDIN-4-YL)OXY]PHENYL}ACRYLONITRILE …
Matched Iupac: … (2E)-3-{3-[(5-ethyl-3-iodo-6-methyl-2-oxo-1,2-dihydropyridin-4-yl)oxy]phenyl}prop-2-enenitrile …

Leptazoline C

Leptazoline C is a polar oxazoline from the Cyanobacterium Leptolyngbya sp. Also see Leptazoline A, Leptazoline B, and Leptazoline D.
Experimental
Matched Iupac: … (3R)-3-hydroxy-3-[(4S,5S)-2-(2-hydroxyphenyl)-5-methyl-4,5-dihydro-1,3-oxazol-4-yl]propanoic acid …

TMP

Experimental
Matched Synonyms: … 5-methyl-5'-uridylic acid ... 5-methyluridine 5'-phosphate ... 5-methyluridine 5'-monophosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-hydroxy-5-methyl-2-oxo-1,2-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

(S)-Fluoxetine

An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration (the antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine).
Experimental
Matched Synonyms: … (S)-N-methyl-3-(4-trifluoromethylphenoxy)-3-phenylpropylamine ... (S)-N-methyl-γ-(4-trifluoromethylphenoxy)-3-phenylpropylamine ... (S)-N-methyl-3-(4-trifluoromethylphenyloxy)-3-(phenyl)propylamine …
Matched Iupac: … methyl[(3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amine …
Matched Description: … An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration (the antidepressant …

Vopratelimab

Vopratelimab is under investigation in clinical trial NCT02904226 (JTX-2011 Alone and in Combination With Anti-PD-1 or Anti-CTLA-4 in Subjects With Advanced and/or Refractory Solid Tumors).
Investigational
Matched Description: … or Anti-CTLA-4 in Subjects With Advanced and/or Refractory Solid Tumors). ... is under investigation in clinical trial NCT02904226 (JTX-2011 Alone and in Combination With Anti-PD-1 …

3-fluoro-4-[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-naphtalen-2-yl)-acetylamino]-benzoic acid

Experimental
Matched Name: … 3-fluoro-4-[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-naphtalen-2-yl)-acetylamino]-benzoic …
Matched Iupac: … 3-fluoro-4-[(2S)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)acetamido]benzoic …

9,10-Deepithio-9,10-Didehydroacanthifolicin

A specific inhibitor of phosphoserine/threonine protein phosphatase 1 and 2a. It is also a potent tumor promoter. (Thromb Res 1992;67(4):345-54 & Cancer Res 1993;53(2):239-41)
Experimental
Matched Iupac: … (2R)-3-[(2S,5R,6R,8S)-8-[(2R,3E)-4-[(2R,4'aR,5R,6'S,8'R,8'aS)-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S ... yl]but-3-en-2-yl]-5-hydroxy-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-hydroxy-2-methylpropanoic ... dioxaspiro[5.5]undecan-2-yl]butyl]-7'-methylidene-hexahydro-3'H-spiro[oxolane-2,2'-pyrano[3,2-b]pyran]-5- …
Matched Description: … (Thromb Res 1992;67(4):345-54 & Cancer Res 1993;53(2):239-41) ... A specific inhibitor of phosphoserine/threonine protein phosphatase 1 and 2a. …

Olezarsen

Olezarsen is an antisense oligonucleotide targeting messenger RNA for apolipoprotein C-III (APOC3).
Investigational
Matched Synonyms: … ALL-P-AMBO-5'-O-(((6-(5-((TRIS(3-(6-(2-ACETAMIDO-2-DEOXY-.BETA. ... 2'-O-(2-METHOXYETHYL)-P-THIOADENYLYL-(3'-O->5'-O)-2'-O-(2-METHOXYETHYL)-P-THIOGUANYLYL-(3 ... -D-GALACTOPYRANOSYLOXY)HEXYLAMINO)-3-OXOPROPOXYMETHYL))METHYL)AMINO-5-OXOPENTANAMIDO)HEXYL))PHOSPHO)- …

5-Alpha-Androstane-3-Beta,17beta-Diol

Experimental
Matched Name: … 5-Alpha-Androstane-3-Beta,17beta-Diol …

(4r)-2-Methylpentane-2,4-Diol

Experimental

3-bromo-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine

Experimental
Matched Name: … 3-bromo-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine …
Matched Iupac: … 3-bromo-5-phenyl-N-[(pyridin-3-yl)methyl]pyrazolo[1,5-a]pyrimidin-7-amine …
Displaying drugs 6901 - 6925 of 12112 in total