Displaying drugs 676 - 700 of 3090 in total
4-Nitrophenyl (3S)-3-({N-[(benzyloxy)carbonyl]-L-phenylalanyl}amino)-5-phenyl-1-pentanesulfonate
Experimental
Matched Synonyms: … 3-[N-[Benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonic acid 4-nitro-phenyl ester …
Relmapirazin
Relmapirazin is under investigation in clinical trial NCT05425719 (Pharmacokinetics and Safety of MB-102 (Relmapirazin) and the Medibeacon Transdermal GFR Measurement System in Evaluation of Kidney Function in Normal and Renal Compromised Subjects).
Investigational
Matched Synonyms: … D-serine, n,n'-((3,6-diamino-2,5-pyrazinediyl)dicarbonyl)bis- ... N,n'-((3,6-diamino-2,5-pyrazinediyl)dicarbonyl)bis(d-serine) …
Matched Description: … Relmapirazin is under investigation in clinical trial NCT05425719 (Pharmacokinetics and Safety of MB- ... in Normal and Renal Compromised Subjects). ... 102 (Relmapirazin) and the Medibeacon Transdermal GFR Measurement System in Evaluation of Kidney Function …
Matched Description: … Relmapirazin is under investigation in clinical trial NCT05425719 (Pharmacokinetics and Safety of MB- ... in Normal and Renal Compromised Subjects). ... 102 (Relmapirazin) and the Medibeacon Transdermal GFR Measurement System in Evaluation of Kidney Function …
Vadadustat
One of the most common symptoms of advanced renal disease is anemia, caused primarily by the inability of the kidney to respond to anemic conditions with a corresponding increase in erythropoietin (EPO) production. The treatment of anemia associated with chronic kidney disease (CKD) has traditionally involved the administration of exogenous...
Approved
Investigational
Matched Synonyms: … N-(5-(3-Chlorophenyl)-3-hydroxypyridine-2-carbonyl)glycine ... Glycine, N-((5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl)carbonyl)- …
Matched Iupac: … 2-{[5-(3-chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid …
Matched Description: … [A244165] Vadadustat is an orally administered inhibitor of HIF-PH with a safety and efficacy profile ... [A244165] A relatively new and alternative treatment option for patients with anemia associated with ... efficacious, the overuse of ESAs has been associated with cardiovascular complications, progression of CKD, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors ... Acids, Heterocyclic …
Matched Iupac: … 2-{[5-(3-chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid …
Matched Description: … [A244165] Vadadustat is an orally administered inhibitor of HIF-PH with a safety and efficacy profile ... [A244165] A relatively new and alternative treatment option for patients with anemia associated with ... efficacious, the overuse of ESAs has been associated with cardiovascular complications, progression of CKD, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors ... Acids, Heterocyclic …
Argifin
Experimental
Matched Name: … Argifin …
Matched Iupac: … methanimidoyl}amino)propyl]-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … methanimidoyl}amino)propyl]-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Captopril
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Approved
Matched Synonyms: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid ... D-2-methyl-3-mercaptopropanoyl-L-proline ... D-3-mercapto-2-methylpropanoyl-L-proline …
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Matched Mixtures name: … Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Diuretics ... captopril and diuretics ... Amino Acids ... Imino Acids …
Matched Products: … HISTIDIN C CAPTOPRIL ITALMEX ... HISTIDIN C (CAPTOPRIL) TABLETAS 50 MG …
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Matched Mixtures name: … Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Diuretics ... captopril and diuretics ... Amino Acids ... Imino Acids …
Matched Products: … HISTIDIN C CAPTOPRIL ITALMEX ... HISTIDIN C (CAPTOPRIL) TABLETAS 50 MG …
Kynurenine
Experimental
Matched Synonyms: … 3-Anthraniloyl-L-alanine ... (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid …
Matched Iupac: … (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
4-Hydroxyphenylglycine
Experimental
Matched Synonyms: … (RS)-2-(4-hydroxyphenyl)glycine ... (+/-)-alpha-amino-4-hydroxybenzeneacetic acid …
Matched Iupac: … 2-amino-2-(4-hydroxyphenyl)acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … 2-amino-2-(4-hydroxyphenyl)acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Tosyl-D-Proline
Experimental
Matched Name: … Tosyl-D-Proline …
Matched Iupac: … (2R)-1-(4-methylbenzenesulfonyl)pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2R)-1-(4-methylbenzenesulfonyl)pyrrolidine-2-carboxylic acid …
L-proline betaine
Experimental
Matched Synonyms: … Proline betaine ... N,N-dimethyl-L-proline …
Matched Name: … L-proline betaine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
Matched Name: … L-proline betaine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
N-Succinyl Methionine
Experimental
Matched Name: … N-Succinyl Methionine …
Matched Iupac: … (2R)-2-(3-carboxypropanamido)-4-(methylsulfanyl)butanoic acid …
Matched Iupac: … (2R)-2-(3-carboxypropanamido)-4-(methylsulfanyl)butanoic acid …
Phosphorus
Approved
Experimental
Matched Synonyms: … Phosphorus, elemental …
Matched Name: … Phosphorus …
Matched Iupac: … phosphorus …
Matched Mixtures name: … Liquid Calcium Mg Phosphorus and Vit.d-3 ... Calci A and D Tab ... PROVITE DAILY MULTIVITAMINS & MINERAL TABLET …
Matched Name: … Phosphorus …
Matched Iupac: … phosphorus …
Matched Mixtures name: … Liquid Calcium Mg Phosphorus and Vit.d-3 ... Calci A and D Tab ... PROVITE DAILY MULTIVITAMINS & MINERAL TABLET …
Narsoplimab
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (226-PROLINE), ANTI-(HUMAN MANNAN-BINDING LECTIN-ASSOCIATED SERINE PROTEASE 2) (HUMAN ... IMMUNOGLOBULIN G4-LAMBDA, ANTI-(HOMO SAPIENS MANNAN-BINDING LECTIN SERINE PROTEASE 2 (MANNOSE-BINDING ... PROTEIN-ASSOCIATED SERINE PROTEASE 2, EC=3.4.21.104) HUMAN MONOCLONAL ANTIBODY .GAMMA.4 HEAVY CHAIN …
Matched Description: … uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic ... consideration as a treatment for hematopoietic stem cell transplant-associated TMA (HSCT-TMA/TA-TMA) and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic ... consideration as a treatment for hematopoietic stem cell transplant-associated TMA (HSCT-TMA/TA-TMA) and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Allantoate
Experimental
Matched Synonyms: … diureido-acetate ... bis[(aminocarbonyl)amino]acetate …
Matched Iupac: … 2,2-bis(carbamoylamino)acetate …
Matched Iupac: … 2,2-bis(carbamoylamino)acetate …
Trestolone acetate
Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed. It is an androgen ester – specifically, the C17 acetate ester of DB05830.
Experimental
Matched Synonyms: … Orgasteron acetate ... Trestolone acetate ... 7α-Methyl-19-nortestosterone acetate …
Matched Name: … Trestolone acetate …
Matched Iupac: … 4,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate …
Matched Description: … Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of ... It is an androgen ester – specifically, the C17 acetate ester of [DB05830]. …
Matched Categories: … Testosterone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Trestolone acetate …
Matched Iupac: … 4,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate …
Matched Description: … Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of ... It is an androgen ester – specifically, the C17 acetate ester of [DB05830]. …
Matched Categories: … Testosterone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Thiarsahydroxy-Cysteine
Experimental
Matched Name: … Thiarsahydroxy-Cysteine …
Matched Iupac: … (2R)-2-amino-3-[(hydroxyarsanyl)sulfanyl]propanoic acid …
Matched Iupac: … (2R)-2-amino-3-[(hydroxyarsanyl)sulfanyl]propanoic acid …
D-Cysteine
A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
Experimental
Matched Synonyms: … D-Cystein ... D-Amino-3-mercaptopropionic acid ... (2S)-2-amino-3-mercaptopropanoic acid …
Matched Name: … D-Cysteine …
Matched Iupac: … (2S)-2-amino-3-sulfanylpropanoic acid …
Matched Description: … A thiol-containing non-essential amino acid that is oxidized to form CYSTINE. …
Matched Salts name: … D-Cysteine hydrochloride monohydrate …
Matched Name: … D-Cysteine …
Matched Iupac: … (2S)-2-amino-3-sulfanylpropanoic acid …
Matched Description: … A thiol-containing non-essential amino acid that is oxidized to form CYSTINE. …
Matched Salts name: … D-Cysteine hydrochloride monohydrate …
Gadobenic acid
Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Synonyms: … Gadobenic acid ... Acide gadobenique ... Acido gadobenico …
Matched Name: … Gadobenic acid …
Matched Description: … other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and ... [A263166] As gadobenate dimeglumine is specifically taken up by hepatocytes and excreted through the ... Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based …
Matched Categories: … gadobenic acid …
Matched Name: … Gadobenic acid …
Matched Description: … other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and ... [A263166] As gadobenate dimeglumine is specifically taken up by hepatocytes and excreted through the ... Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based …
Matched Categories: … gadobenic acid …
Norethisterone
Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Description: … derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol ... [A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its ... endometriosis, and was not marketed for use as an oral contraceptive until 1962. …
Matched Mixtures name: … Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate …
Matched Salts name: … Norethisterone acetate …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Genito Urinary System and Sex Hormones ... norethisterone and estrogen …
Matched Products: … Norethindrone Acetate ... Norethindrone acetate …
Matched Mixtures name: … Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate …
Matched Salts name: … Norethisterone acetate …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Genito Urinary System and Sex Hormones ... norethisterone and estrogen …
Matched Products: … Norethindrone Acetate ... Norethindrone acetate …
Ziltivekimab
Ziltivekimab is under investigation in clinical trial NCT06200207 (A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation).
Investigational
Matched Synonyms: … Immunoglobulin g1 (255-tyrosine,257-threonine,259-glutamic acid), anti-(human interleukin 6) (human monoclonal …
Matched Description: … Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
LTI-03
LTI-03 is a caveolin-1 Scaffolding Domain 7-Mer
Investigational
Matched Synonyms: … L-threonine, l-phenylalanyl-l-threonyl-l-threonyl-l-phenylalanyl-l-threonyl-l-valyl- …
Methadone
Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission. It also has a...
Approved
Matched Description: … However, it also has a unique pharmacokinetic profile. ... Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate ... of serotonin and norepinephrine uptake. …
Matched Salts name: … Methadone hydrochloride …
Matched Products: … Methadone Hydrochloride ... Methadone hydrochloride ... Methadone Hydrocloride …
Matched Salts name: … Methadone hydrochloride …
Matched Products: … Methadone Hydrochloride ... Methadone hydrochloride ... Methadone Hydrocloride …
Quingestanol acetate
Experimental
Matched Synonyms: … Quingestanol acetate ... Norethindrone acetate 3-cyclopentyl enol ether …
Matched Name: … Quingestanol acetate …
Matched Iupac: … )-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate …
Matched Name: … Quingestanol acetate …
Matched Iupac: … )-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate …
Phorbol 12-myristate 13-acetate diester
Phorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs).
Investigational
Matched Synonyms: … Phorbol myristate acetate ... Tetradecanoylphorbol acetate ... Phorbol 12-myristate 13-acetate …
Matched Name: … Phorbol 12-myristate 13-acetate diester …
Matched Description: … Phorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs). …
Matched Name: … Phorbol 12-myristate 13-acetate diester …
Matched Description: … Phorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs). …
N-Dimethyl-Lysine
Experimental
Matched Name: … N-Dimethyl-Lysine …
Matched Iupac: … (2S)-2-amino-6-(dimethylamino)hexanoic acid …
Matched Iupac: … (2S)-2-amino-6-(dimethylamino)hexanoic acid …
Displaying drugs 676 - 700 of 3090 in total