This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Quingestanol acetate
- DrugBank Accession Number
- DB14679
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Quingestanol acetate (DB14679)
- Weight
- Average: 408.582
Monoisotopic: 408.266445019 - Chemical Formula
- C27H36O3
- Synonyms
- Norethindrone acetate 3-cyclopentyl enol ether
- Quingestanol acetate
- External IDs
- W 4540
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAbciximab Quingestanol acetate may decrease the anticoagulant activities of Abciximab. Acenocoumarol Quingestanol acetate may decrease the anticoagulant activities of Acenocoumarol. Alteplase Quingestanol acetate may decrease the anticoagulant activities of Alteplase. Ancrod Quingestanol acetate may decrease the anticoagulant activities of Ancrod. Anistreplase Quingestanol acetate may decrease the anticoagulant activities of Anistreplase. Antithrombin Alfa Quingestanol acetate may decrease the anticoagulant activities of Antithrombin Alfa. Antithrombin III human Quingestanol acetate may decrease the anticoagulant activities of Antithrombin III human. Apixaban Quingestanol acetate may decrease the anticoagulant activities of Apixaban. Ardeparin Quingestanol acetate may decrease the anticoagulant activities of Ardeparin. Argatroban Quingestanol acetate may decrease the anticoagulant activities of Argatroban. 
Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Active Moieties
Name Kind UNII CAS InChI Key Norethisterone prodrug T18F433X4S 68-22-4 VIKNJXKGJWUCNN-XGXHKTLJSA-N
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- M33GGZ63KG
- CAS number
- 3000-39-3
- InChI Key
- FLGJKPPXEKYCBY-AKCFYGDASA-N
- InChI
- InChI=1S/C27H36O3/c1-4-27(30-18(2)28)16-14-25-24-11-9-19-17-21(29-20-7-5-6-8-20)10-12-22(19)23(24)13-15-26(25,27)3/h1,9,17,20,22-25H,5-8,10-16H2,2-3H3/t22-,23+,24+,25-,26-,27-/m0/s1
- IUPAC Name
- (1R,3aS,3bR,9aR,9bS,11aS)-7-(cyclopentyloxy)-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
- SMILES
- [H][C@@]12CC[C@@](OC(C)=O)(C#C)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCC(OC4CCCC4)=CC3=CC[C@@]21[H]
References
- General References
- Not Available
- External Links
- ChemSpider
- 17136
- ChEBI
- 135661
- ChEMBL
- CHEMBL2105291
- Wikipedia
- Quingestanol_acetate
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.00175 mg/mL ALOGPS logP 5.67 ALOGPS logP 4.76 Chemaxon logS -5.4 ALOGPS pKa (Strongest Basic) -4.8 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 35.53 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 120.29 m3·mol-1 Chemaxon Polarizability 49.19 Å3 Chemaxon Number of Rings 5 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at September 05, 2018 17:06 / Updated at February 21, 2021 18:54