This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Quingestanol acetate
DrugBank Accession Number
DB14679
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 408.582
Monoisotopic: 408.266445019
Chemical Formula
C27H36O3
Synonyms
  • Norethindrone acetate 3-cyclopentyl enol ether
  • Quingestanol acetate
External IDs
  • W 4540

Pharmacology

Indication

Not Available

Pharmacology
Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Contraindications & Blackbox Warnings
Contraindications
Avoid life-threatening adverse drug events
Improve clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events & improve clinical decision support.
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
Learn more
Improve decision support & research outcomes with our structured adverse effects data.
Learn more
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbciximabQuingestanol acetate may decrease the anticoagulant activities of Abciximab.
AcenocoumarolQuingestanol acetate may decrease the anticoagulant activities of Acenocoumarol.
AlteplaseQuingestanol acetate may decrease the anticoagulant activities of Alteplase.
AncrodQuingestanol acetate may decrease the anticoagulant activities of Ancrod.
AnistreplaseQuingestanol acetate may decrease the anticoagulant activities of Anistreplase.
Antithrombin AlfaQuingestanol acetate may decrease the anticoagulant activities of Antithrombin Alfa.
Antithrombin III humanQuingestanol acetate may decrease the anticoagulant activities of Antithrombin III human.
ApixabanQuingestanol acetate may decrease the anticoagulant activities of Apixaban.
ArdeparinQuingestanol acetate may decrease the anticoagulant activities of Ardeparin.
ArgatrobanQuingestanol acetate may decrease the anticoagulant activities of Argatroban.
Interactions
Identify potential medication risks
Easily compare up to 40 drugs with our drug interaction checker.
Get severity rating, description, and management advice.
Learn more
Food Interactions
Not Available

Products

Products2
Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now
Active Moieties
NameKindUNIICASInChI Key
NorethisteroneprodrugT18F433X4S68-22-4VIKNJXKGJWUCNN-XGXHKTLJSA-N

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
M33GGZ63KG
CAS number
3000-39-3
InChI Key
FLGJKPPXEKYCBY-AKCFYGDASA-N
InChI
InChI=1S/C27H36O3/c1-4-27(30-18(2)28)16-14-25-24-11-9-19-17-21(29-20-7-5-6-8-20)10-12-22(19)23(24)13-15-26(25,27)3/h1,9,17,20,22-25H,5-8,10-16H2,2-3H3/t22-,23+,24+,25-,26-,27-/m0/s1
IUPAC Name
(1R,3aS,3bR,9aR,9bS,11aS)-7-(cyclopentyloxy)-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
SMILES
[H][C@@]12CC[C@@](OC(C)=O)(C#C)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCC(OC4CCCC4)=CC3=CC[C@@]21[H]

References

General References
Not Available
ChemSpider
17136
ChEBI
135661
ChEMBL
CHEMBL2105291
Wikipedia
Quingestanol_acetate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.00175 mg/mLALOGPS
logP5.67ALOGPS
logP4.76ChemAxon
logS-5.4ALOGPS
pKa (Strongest Basic)-4.8ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area35.53 Å2ChemAxon
Rotatable Bond Count4ChemAxon
Refractivity120.29 m3·mol-1ChemAxon
Polarizability49.19 Å3ChemAxon
Number of Rings5ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at September 05, 2018 17:06 / Updated at February 21, 2021 18:54