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Displaying drugs 701 - 725 of 1076 in total
Experimental
Matched Synonyms: … beta-mercaptoethanol …
Investigational
Matched Synonyms: … BETA-1B-GLYCOPROTEIN …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Beta-Globulins …
Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. Clozapine displays affinity to various neuroreceptors with a particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and deeming it "atypical". . This low affinity to dopamine receptors results in fewer extrapyramidal side effects,...
Approved
Matched Description: … side effects, notably gastrointestinal hypomotility and orthostatic hypotension. ... particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and ... [A185747] However, its promiscuity toward the muscarinic and adrenergic receptors can result in other …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … CLOZAPIN BETA 25MG ... CLOZAPIN BETA 50MG ... CLOZAPIN BETA 100MG …
Betameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred to as Meprodine). Betameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of opioids,...
Experimental
Illicit
Matched Synonyms: … beta-meprodine ... beta-1-Methyl-3-ethyl-4-phenyl-4-propionoxy-piperidin ... beta-3-Ethyl-1-methyl-4-phenyl-4-propionoxypiperidine …
Matched Description: … as well as itching, nausea, and respiratory depression. ... The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
Investigational
Matched Synonyms: … 5-cholesten-3.beta.-25-diol-3-sulfate ... 5-cholesten-3.beta., 25-diol 3-sulfate ... 25-hydroxycholest-5-en-3.beta.-yl hydrogen sulfate …
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … beta-(4-Chlorophenyl)gaba ... beta-(Aminomethyl)-p-chlorohydrocinnamic acid ... beta-(p-Chlorophenyl)-gamma-aminobutyric acid …
Matched Description: … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … Beta-D-Fructopyranose …
Experimental
Matched Name: … Beta-3-Cysteine …
Nonacog beta pegol is a recombinant coagulation factor IX derivative. It is produced without animal-derived materials and with an attached 40kDa polyethylene glycol (PEG) molecule for peptide activation by a site-directed glycoPEGylation. Once activated, the activation molecule with PEG is cleaved to leave the activated factor IX (Factor IXa). Nonacog...
Approved
Investigational
Matched Synonyms: … Nonacog beta pegol …
Matched Name: … Nonacog beta pegol …
Matched Description: … [A31496] Nonacog beta pegol was developed by Novo Nordisk and received its first global approval by the ... It is produced without animal-derived materials and with an attached 40kDa polyethylene glycol (PEG) ... Once activated, the activation molecule with PEG is cleaved to leave the activated factor IX (Factor …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Extracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal dietary supplements . Most commonly, it is an active ingredient in skincare and cosmetic products...
Approved
Matched Synonyms: … beta-Arbutin ... 4-Hydroxyphenyl-beta-D-glucopyranoside ... Hydroquinone-O-beta-D-glucopyranoside …
Matched Description: … in the _Ericaceae_ family, arbutin is a beta-D-glucopyranoside of [DB09526]. ... and [DB09526] [F43]. ... Extracted from the dried leaves of bearberry plant in the genus _Arctostaphylos_ and other plants commonly …
Experimental
Matched Synonyms: … beta-Naphthylsulfonic acid ... beta-Naphthalenesulfonic acid …
Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines Agency (EMA) in 2005. The Committee...
Approved
Investigational
Matched Description: … Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors ... Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines ... The major concern was that efficacy had not been sufficiently shown. …
Matched Products: … AGOMELATIN BETA 25MG FTA …
Willardiine is a compound isolated from seeds of Acacia willariana.
Experimental
Matched Synonyms: … beta-(2,4-Dihydroxypyrimidin-1-yl)alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … beta-Cryptoxanthin …
Matched Categories: … Diet, Food, and Nutrition …
Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients).
Investigational
Matched Synonyms: … Anti-tgf-beta monoclonal antibody nis793 …
Matched Description: … in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy ... Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … 1-N-acetyl-beta-D-glucosamine …
Matched Name: … N-beta-D-glucopyranosylacetamide …
Experimental
Matched Synonyms: … Methyl 6-deoxy-beta-L-galactopyranoside …
Matched Name: … Methyl beta-L-fucopyranoside …
Glycyrrhizic acid is extracted from the root of the licorice plant; Glycyrrhiza glabra. It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and biological activities. When extracted from the plant, it can be obtained in the form of ammonium glycyrrhizin and mono-ammonium glycyrrhizin. Glycyrrhizic...
Approved
Experimental
Matched Synonyms: … 18-beta-Glycyrrhizic acid …
Matched Description: … It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and ... When extracted from the plant, it can be obtained in the form of ammonium glycyrrhizin and mono-ammonium ... [T204] Glycyrrhizic acid has been developed in Japan and China as a hepatoprotective drug in cases of …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy …
Experimental
Matched Name: … Beta-(2-Naphthyl)-Alanine …
Experimental
Matched Synonyms: … beta-D-Glucopyranuronic acid …
Matched Name: … beta-D-glucuronic acid …
2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and Recurrent Mantle Cell Lymphoma, among others.
Investigational
Matched Synonyms: … 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil ... 2'-Fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil …
Matched Description: … Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Description: … stress disorder, and symptoms of menopause, among others. ... of serotonin reuptake and has little effect on other neurotransmitters. ... [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. …
Matched Products: … PAROXETIN BETA 10MG ... PAROXETIN BETA 20MG ... PAROXETIN BETA 30MG …
Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin) is the 5-formyl derivative of tetrahydrofolic acid, a necessary co-factor in the body. Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the...
Approved
Matched Description: … Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary ... activity, the two commercially available forms have been shown to be pharmacokinetically identical and ... As folate analogs, leucovorin and levoleucovorin are both used to counteract the toxic effects of folic …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives …
Matched Products: … Bulk Vial) 10mg/ml …
A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale,...
Approved
Investigational
Matched Synonyms: … 1-beta-D-Arabinofuranosylcytosine ... Cytosine-1-beta-D-arabinofuranoside ... 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone …
Matched Description: … It also has antiviral and immunosuppressant properties. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... cytarabine and daunorubicin ... Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Synonyms: … beta-D-glucose-6-phosphate ... beta-D-Glucose 6-phosphic acid ... beta-D-glucose 6-(dihydrogen phosphate) …
Matched Name: … beta-D-glucose 6-phosphate …
Displaying drugs 701 - 725 of 1076 in total