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Displaying drugs 7276 - 7300 of 10568 in total
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Eniluracil, which was previously under development by GlaxoSmithKline (GSK), is being developed by Adherex to enhance the therapeutic value and effectiveness of 5-fluorouracil (5-FU), one of the world’s most widely-used oncology agents. 5-FU is widely used in the U.S. and is often first or second line therapy for a variety...
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
REP8839 is a novel methionyl-tRNA synthetase (MetS) inhibitor being developed by Replidyne (GlaxoSmithKline licensed REP8839 to Replidyne in June of 2003).
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
MK-1775 has been used in trials studying the treatment of LYMPHOMA, Neoplasms, Ovarian Cancer, Tongue Carcinoma, and Adult Glioblastoma, among others.
Investigational
Matched Iupac: … 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
PF-04958242 has been used in trials studying the basic science and treatment of Schizophrenia and Hearing Loss, Sensorineural.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Dianicline has been used in trials studying the treatment of Smoking, Smoking Cessation, and Tobacco Use Cessation.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pumosetrag has been used in trials studying Gastroesophageal Reflux Disease.
Investigational
Matched Iupac: … N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-7-oxo-4H,7H-thieno[3,2-b]pyridine-6-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Gsk356278 has been used in trials studying the treatment and basic science of Anxiety Disorders, Huntington Disease, Depressive Disorder, Huntingtons Disease, and Depressive Disorder, Major, among others.
Investigational
Matched Iupac: … 5-{5-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-1,3,4-oxadiazol-2-yl}-1-ethyl-N-(oxan-4-yl)-1H-pyrazolo[ …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Brilacidin is under investigation for the supportive care of Mucositis, Stomatitis, Mouth Diseases, and Head and Neck Neoplasms.
Investigational
Matched Salts cas: … 1224095-99-1
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Avexitide is under investigation in clinical trial NCT02996812 (Evaluation of Single Ascending Doses of Subcutaneous Exendin 9-39 in Patients With Post-Bariatric Hypoglycemia).
Investigational
Matched Iupac: … (4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S,2S)-1-{[(1S)-1-{[(1S)-1-{ ... [(1S)-1-{[(1S)-5-amino-1-{[(1S)-2-carbamoyl-1-{[({2-[(2S)-2-{[(1S)-1-{[(1S)-1-[({[(2S)-1-[(2S)-2-[(2S ... )-2-[(2S)-2-{[(1S)-1-carbamoyl-2-hydroxyethyl]carbamoyl}pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl ... ]pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}methyl)carbamoyl]-2-hydroxyethyl]carbamoyl}-2-hydroxyethyl ... ]carbamoyl}pyrrolidin-1-yl]-2-oxoethyl}carbamoyl)methyl]carbamoyl}ethyl]carbamoyl}pentyl]carbamoyl}-3 …
Matched Categories: … Glucagon-Like Peptide 1
Rocacetrapib is under investigation in clinical trial NCT02156544 (Study to Investigate the Safety/Tolerability and Pharmacokinetics/Pharmacodynamics of CKD-519).
Investigational
Matched Iupac: … en-1-yl}methyl)-4-methyl-1,3-oxazolidin-2-one ... 3,5-bis(trifluoromethyl)phenyl]-3-({2-[4-fluoro-2-methoxy-5-(propan-2-yl)phenyl]-5,5-dimethylcyclohex-1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
AMG-337 is under investigation in clinical trial NCT03147976 (QUILT-3.036: AMG 337 in Subjects With Advanced or Metastatic Solid Tumors).
Investigational
Matched Iupac: … 6-[(1R)-1-[8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
GW810781 is under investigation in clinical trial NCT00046332 (A Study Comparing 4 Doses of GW810781 Versus Placebo in Hiv-infected Patients).
Investigational
Matched Iupac: … (2Z)-1-{5-[(4-fluorophenyl)methyl]furan-2-yl}-3-hydroxy-3-(1H-1,2,4-triazol-3-yl)prop-2-en-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Iupac: … 4-benzyl-1-{[2,4'-bipyridine]-3-carbonyl}piperidin-4-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bermekimab is under investigation in clinical trial NCT01384630 (Safety, Pharmacokinetics, and Efficacy of RA-18C3 in Subjects With Moderate to Severe Psoriasis).
Investigational
Almonertinib is a third-generation EGFR tyrosine kinase inhibitor targeting EGFR-sensitizing and T790M resistance mutations.[A231859, A231864, A231869] It is being investigated against advanced or metastatic EGFR-mutated non-small cell lung cancer (NSCLC).
Investigational
Matched Iupac: … N-(5-{[4-(1-cyclopropyl-1H-indol-3-yl)pyrimidin-2-yl]amino}-2-{[2-(dimethylamino)ethyl](methyl)amino} …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Vet approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …
BMS-690514 has been investigated for the treatment of Breast Cancer.
Investigational
Matched Iupac: … (3R,4R)-4-amino-1-({4-[(3-methoxyphenyl)amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl}methyl)piperidin-3-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
BMS-903452 has been used in trials studying the treatment of Diabetes.
Investigational
Matched Iupac: … 5-chloro-4-{[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]oxy}-1-(2-fluoro-4-methanesulfonylphenyl)-1,2-dihydropyridin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
MK0767 has been used in trials studying the treatment of Dyslipidemia, Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, and Diabetes Mellitus, Type II, among others.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
RRx-001 has been used in trials studying the treatment of Lymphomas, Brain Metastases, Cholangiocarcinoma, Colorectal Neoplasms, and Malignant Solid Tumor, among others.
Investigational
Matched Iupac: … 2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Butafenacil is under investigation in clinical trial NCT03760328 (Effect of Upper Airway Stimulation in Patients With Obstructive Sleep Apnea).
Investigational
Matched Iupac: … prop-2-en-1-yl 2-{2-chloro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 7276 - 7300 of 10568 in total