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Displaying drugs 7451 - 7475 of 10532 in total
An antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems. [PubChem]
Experimental
Matched Iupac: … (2E)-N-[(2S)-1-hydroxy-3-[(R)-(methylsulfanyl)methanesulfinyl]propan-2-yl]-3-(6-methyl-2,4-dioxo-1,2,3,4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ranirestat is a structurally novel and stereospecifically potent aldose reductase (AKR1B; EC 1.1.1.21) inhibitor, which contains a succinimide ring that undergoes ring-opening at physiological pH levels. It has been used in trials studying the treatment of Mild to Moderate Diabetic Sensorimotor Polyneuropathy.
Investigational
Matched Iupac: … ]-1',2,3',5-tetrone ... (3R)-2'-[(4-bromo-2-fluorophenyl)methyl]-2',3'-dihydro-1'H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Fevipiprant has been used in trials studying the treatment of Asthma, Atopic Dermatitis, and Allergic Rhinitis.
Investigational
Matched Iupac: … 2-(1-{[4-methanesulfonyl-2-(trifluoromethyl)phenyl]methyl}-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CH5132799 has been used in trials studying the treatment of Solid Tumors.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
ABP-700 is under investigation in clinical trial NCT02800590 (Study to Investigate the Safety and Efficacy of 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy).
Investigational
Matched Iupac: … 1-(methoxycarbonyl)cyclopropyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cambinol is a beta-naphtol derivative that inhibits NAD-dependant deacetylases to reduce cell survival under stress. This activity is currently being investigated for its use as a cancer treatment.
Experimental
Matched Iupac: … 5-[(2-hydroxynaphthalen-1-yl)methyl]-6-phenyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Triazavirin is a guanine nucleotide analog antiviral originally developed in Russia that has shown efficacy against influenza A and B, including the H5N1 strain.[A191709,A191625,A191916] It appears that Triazavirin has shown promise in reducing influenza disease severity and associated complications. Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating...
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pexmetinib is under investigation in clinical trial NCT04074967 (Study of ARRY-614 Plus Either Nivolumab or Ipilimumab).
Investigational
Matched Iupac: … 3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-[(5-fluoro-2-{[1-(2-hydroxyethyl)-1H-indazol-5- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Gusperimus has been used in trials studying the treatment of Lupus Nephritis, Wegeners Granulomatosis, and Wegener's Granulomatosis.
Investigational
Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed. It is an androgen ester – specifically, the C17 acetate ester of DB05830.
Experimental
Matched Iupac: … -4,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1- …
MV130 contains different components of whole heat-inactivated gram-positive and -negative bacteria that are involved in upper and lower respiratory infections. These include streptococcus pneumoniae and staphylococcus aureus. Though studies have shown that it reduces the rate of infections in recurrent respiratory tract infections (RRTIs), the complete mechanisms are not fully...
Investigational
PF-05230907 is a recombinant activated Factor X variant.
Investigational
N-methylnicotinamide is an experimental drug with no approved indication or marketed formulation. It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by measuring N-methylnicotinamide in the urine.
Experimental
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … (2S)-1-[(8aR)-octahydropyrrolo[1,2-a]pyrimidin-1-yl]-4-methylpentan-2-amine …
Experimental
Matched Iupac: … N-[(2S)-4,4,4-trifluoro-3-oxo-1-phenylbutan-2-yl]acetamide …
Experimental
Illicit
Investigational
Matched Iupac: … 4-{4,5,7,11-tetrahydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl}pentanoic acid …
Experimental
Matched Iupac: … (2S)-1-hydroxy-3-(1H-imidazol-5-yl)propan-2-aminium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Iupac: … 1-[(4-fluorophenyl)methyl]-N-(piperidin-4-yl)-1H-1,3-benzodiazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 7451 - 7475 of 10532 in total