Afuresertib

DB11648InvestigationalSmall molecule

Afuresertib has been used in trials studying the treatment of Cancer and Neoplasms, Haematologic.

Chemical structure of Afuresertib
Formula / weight
C18H17Cl2FN4OS · 427.32 g/mol (avg)
Code names
GSK-2110183 · GSK-2110183C

Resolves to

Compound
UNII8739X25QI3CAS1047644-62-1ChEMBLCHEMBL2219422ChEBI131168PubChem46843057
Structure
InChIKeyAFJRDFWMXUECEW-LBPRGKRZSA-NSMILESCN1N=CC(Cl)=C1C1=C(Cl)SC(=C1)C(=O)N[C@H](CN)CC1=CC=CC(F)=C1
Targets
P31749AKT1

What you can answer from here — as of September 16, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
16Clinical trialsPhase, status and sponsor resolved per trial
Sign in
1+ReferenceStructured and connected to the statements they support
Sign in

Which drugs share a target with Afuresertib, and which of those have an active Phase 3 trial?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In