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Displaying drugs 51 - 75 of 1766 in total
Nedosiran is an RNA interference targeting hepatic lactate dehydrogenase, the enzyme responsible for the conversion of glyoxylate to oxalate. Oxalate, particularly calcium oxalate, precipitation is the main cause of kidney stones formation; therefore, blocking the production of oxalate can help alleviate renal symptoms. Nedosiran was approved by the FDA on...
Approved
Investigational
Matched Description: … October 2nd, 2023, under the brand name RIVFLOZA to lower urinary oxalate levels in children 9
Alnus rhombifolia pollen is the pollen of the Alnus rhombifolia plant. Alnus rhombifolia pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 9 Tree Mix …
Besilesomab is a mouse monoclonal antibody labelled with the radioactive isotope technetium-99m for determining the location of inflammation/infection in peripheral bone in adults with suspected osteomyelitis [FDA Label]. Utilised only as a diagnostic agent, besilesomab is currently approved by the EMEA for marketing and use in various European countries like...
Approved
Sulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is also found in garlic, onions and broccoli. People take sulfur...
Approved
Matched Mixtures name: … Sodium Sulfacetamide 9% - Sulfur 4% ... Sodium Sulfacetamide 9 Sulfur 4.5 Wash ... Sodium Sulfacetamide 9 Sulfur 4.5 Wash …
Inclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 (PCSK9), which is a serine protease that regulates plasma low-density lipoprotein cholesterol (LDL-C) levels. By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and plasma...
Approved
Investigational
Matched Description: … synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9
Matched Categories: … Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Inhibitors …
Ulmus crassifolia pollen is the pollen of the Ulmus crassifolia plant. Ulmus crassifolia pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 9 Tree Mix …
Methyl nicotinate is the methyl ester of DB00627 that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. For veterinary purposes, methyl nicotinate is used to...
Approved
Betula lenta pollen is the pollen of the Betula lenta plant. Betula lenta pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 9 Tree Mix …
Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. Minocycline was granted FDA approval...
Approved
Investigational
Matched Description: … [A190723] Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the …
Technetium (99mTc) medronic acid is a pharmaceutical product used in nuclear medicine imaging. It is composed of a technetium ion complexed with medronic acid, a type of bisphosphonate. Like other bisphosphonates used in the treatment of osteoporosis, medronic acid binds to the hydroxyapatite crystals within bone, and in this way...
Approved
Matched Salts cas: … 65871-22-9
Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Synonyms: … (17alpha)-17-ethynyl-17-hydroxyestra-4,8(14),9-trien-3-one …
Matched Salts cas: … 51-98-9
Quercus alba pollen, or oak white pollen, is a non-standardized allergen extract used for the diagnosis and treatment of allergic disease to grass pollen. It can be subcutaneously administered to initiate an immune response in case of an allergic reaction. Diagnostic allergenic extracts are primarily indicated for establishing clinical relevance...
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 9 Tree Mix …
Voxilaprevir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Palbociclib is a piperazine pyridopyrimidine that acts in the cell cycle machinery. It is a second generation cyclin-dependent kinase inhibitor selected from a group of pyridopyrimidine compounds due to its favorable physical and pharmaceutical properties. Palbociclib was developed by Pfizer Inc after the discovery that identified the cyclin-dependent kinases as...
Approved
Investigational
Fraxinus americana pollen is the pollen of the Fraxinus americana plant. Fraxinus americana pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 9 Tree Mix …
Acer saccharinum pollen is the pollen of the Acer saccharinum plant. Acer saccharinum pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix …
Approved
Investigational
Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Bupivacaine is a widely used local anesthetic agent.
Approved
Investigational
Matched Salts cas: … 73360-54-0 …
Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Matched Salts cas: … 1098065-76-9
Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid antiseptic. The compound may also be used commonly in various commercial cosmetic anti-aging...
Approved
Elivaldogene autotemcel is a gene therapy consisting of genetically modified autologous cells. It is used to provide functional copies of human adrenoleukodystrophy protein (ALDP) in patients with adrenoleukodystrophy, an X-linked genetic disorder characterized by missing or non-functional ABCD1 gene that codes for ALDP. ALDP is a key protein that normally...
Approved
Blinatumomab is a BiTE-class (bi-specific T-cell engager) constructed monoclonal antibody formed by the recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through a short peptide linker.[A254836,L44311] CD3 is an antigen expressed on the surface of T-cells, while CD19 is mostly expressed on the surface of...
Approved
Investigational
Fludarabine is a chemotherapeutic agent used in the treatment of hematological malignancies. It is commonly marketed under the brand name Fludara.
Approved
Matched Iupac: … (2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Salts cas: … 75607-67-9
Technetium Tc-99m tilmanocept is a radiopharmaceutical diagnostic imaging agent approved by the U.S. Food and Drug Administration (FDA) for the imaging of lymph nodes with or without scintigraphic imaging. It is a macromolecule consisting of multiple units of diethylenetriaminepentaacetic acid (DTPA) and mannose, each covalently attached to a 10 kDa...
Approved
Investigational
Displaying drugs 51 - 75 of 1766 in total