Displaying drugs 51 - 75 of 241 in total
Gadobenic acid
Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Iupac: … gadolinium(3+) ion 4-carboxy-8,11-bis(carboxylatomethyl)-5-(carboxymethyl)-1-phenyl-2-oxa-5,8,11-triazatridecan …
Matched Description: … [A263166] As gadobenate dimeglumine is specifically taken up by hepatocytes and excreted through the ... other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and …
Matched Description: … [A263166] As gadobenate dimeglumine is specifically taken up by hepatocytes and excreted through the ... other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and …
Zinc
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound...
Approved
Investigational
Matched Description: … polymorphism of the common polymorphism in zinc transporter _SLC30A8/ZnT8_ may increase susceptibility to type 2 ... A metallic element of atomic number 30 and atomic weight 65.38. ... important role in protein synthesis and in cell division. …
Matched Mixtures name: … Acti-cal/mag 2:1 + Zinc and D Caplet ... Chelated Cal-mag(2:1)with Zn Vit.c and D ... Calcium and Magnesium 1:1 Plus Tablets …
Matched Categories: … Diet, Food, and Nutrition ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Mixtures name: … Acti-cal/mag 2:1 + Zinc and D Caplet ... Chelated Cal-mag(2:1)with Zn Vit.c and D ... Calcium and Magnesium 1:1 Plus Tablets …
Matched Categories: … Diet, Food, and Nutrition ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Ansuvimab
Infection with pathogenic filoviruses, such as Zaire ebolavirus (Ebola virus, EBOV), can cause severe hemorrhagic fever in humans, resulting in frequent outbreaks with case fatality rates as high as 90%.[A225933, A225938] Virtually all steps of the EBOV lifecycle have been targeted for therapeutic development. However, to date, the most successful...
Approved
Investigational
Matched Description: … [A225933] Ansuvimab, formerly mAb114, is a fully human IgG1 mAb derived from a survivor of the 1995 Kikwit ... to be superior, with improved patient survival and faster viral clearance rates. ... [maftivimab]), the now approved ansuvimab, and ZMapp, which remains in clinical trials. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Fexinidazole
Human African trypanosomiasis (HAT, also colloquially referred to as sleeping sickness), caused by T. brucei gambiense and T. brucei rhodesiense, remains a moderate risk (>1/10,000 inhabitants per year in endemic areas) despite focussed control efforts. Transmitted by the bite of an infected tsetse fly, HAT is biphasic with a first...
Approved
Investigational
Matched Iupac: … 1-methyl-2-{[4-(methylsulfanyl)phenoxy]methyl}-5-nitro-1H-imidazole …
Matched Description: … . brucei gambiense_ and _T. brucei rhodesiense_, remains a moderate risk (>1/10,000 inhabitants per year ... Human African trypanosomiasis (HAT, also colloquially referred to as sleeping sickness), caused by _T ... [nifurtimox]/[eflornithine] combination therapy (NECT), though [melarsoprol] is highly toxic and each …
Matched Categories: … MATE 2 Inhibitors ... MATE 2-K Inhibitors ... Agents Against Leishmaniasis and Trypanosomiasis ... MATE 1 Inhibitors ... Antiparasitic Products, Insecticides and Repellents …
Matched Description: … . brucei gambiense_ and _T. brucei rhodesiense_, remains a moderate risk (>1/10,000 inhabitants per year ... Human African trypanosomiasis (HAT, also colloquially referred to as sleeping sickness), caused by _T ... [nifurtimox]/[eflornithine] combination therapy (NECT), though [melarsoprol] is highly toxic and each …
Matched Categories: … MATE 2 Inhibitors ... MATE 2-K Inhibitors ... Agents Against Leishmaniasis and Trypanosomiasis ... MATE 1 Inhibitors ... Antiparasitic Products, Insecticides and Repellents …
Propiolactone
Propiolactone is a lactone compound with a four-membered ring. It is a colorless liquid with a pungent slightly sweet odor. Propiolactone is a disinfectant used for the sterilization of blood plasma, vaccines, tissue grafts, surgical instruments, and enzymes. It has been used against bacteria, fungi, and virus. It is currently...
Approved
Withdrawn
Matched Iupac: … oxetan-2-one …
Matched Description: … It has been used against bacteria, fungi, and virus. ... disinfectant used for the sterilization of blood plasma, vaccines, tissue grafts, surgical instruments, and …
Matched Description: … It has been used against bacteria, fungi, and virus. ... disinfectant used for the sterilization of blood plasma, vaccines, tissue grafts, surgical instruments, and …
Ivosidenib
Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. IDH1 is an enzyme that is often mutated and overexpressed in some cancers, leading to aberrant cell growth and proliferation. Ivosidenib inhibits mutated IDH1, blocking the enzymatic activity and further differentiation of cancer cells. Ivosidenib was granted accelerated approval by the FDA...
Approved
Investigational
Matched Iupac: … (2S)-2-(2-chlorophenyl)-2-{1-[(2S)-1-(4-cyanopyridin-2-yl)-5-oxopyrrolidin-2-yl]-N-(5-fluoropyridin-3 …
Matched Description: … Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. ... [L48781] In February 2023, the EMA's Committee for Medicinal Products for Human Use (CHMP) adopted ... and proliferation. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Heterocyclic Compounds, 1-Ring ... Isocitrate Dehydrogenase 1 Inhibitor ... Isocitrate Dehydrogenase-1 Inhibitors …
Matched Description: … Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. ... [L48781] In February 2023, the EMA's Committee for Medicinal Products for Human Use (CHMP) adopted ... and proliferation. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Heterocyclic Compounds, 1-Ring ... Isocitrate Dehydrogenase 1 Inhibitor ... Isocitrate Dehydrogenase-1 Inhibitors …
Fidaxomicin
Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by Clostridioides (formerly Clostridium) difficile in adult and pediatric patients over the age of 6 months. Fidaxomicin is a naturally-occurring 18-member macrocycle derived from fermentation. Because fidaxomicin contains an 18-membered lactone ring in its structure, it is...
Approved
Matched Iupac: … methylpropanoyl)oxy]oxan-2-yl]oxy}-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-2-oxo ... -1-oxacyclooctadeca-3,5,9,13,15-pentaen-3-yl]methoxy}-4-hydroxy-5-methoxy-2-methyloxan-3-yl 3,5-dichloro ... -2-ethyl-4,6-dihydroxybenzoate ... 3S,4S,5S,6R)-6-{[(3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-{[(2R,3S,4R,5S)-3,4-dihydroxy-6,6-dimethyl-5-[(2- …
Matched Description: … bactericidal activity is time-dependent, and not concentration-dependent. ... the treatment of diarrhea caused by _Clostridioides_ (formerly _Clostridium_) _difficile_ in adult and ... [A190492] The antibacterial activity of fidaxomicin is distinct from macrolides and rifamycins, as the …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Description: … bactericidal activity is time-dependent, and not concentration-dependent. ... the treatment of diarrhea caused by _Clostridioides_ (formerly _Clostridium_) _difficile_ in adult and ... [A190492] The antibacterial activity of fidaxomicin is distinct from macrolides and rifamycins, as the …
Matched Categories: … Alimentary Tract and Metabolism …
Clozapine
Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. Clozapine displays affinity to various neuroreceptors with a particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and deeming it "atypical". . This low affinity to dopamine receptors results in fewer extrapyramidal side effects,...
Approved
Matched Iupac: … 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaene …
Matched Description: … side effects, notably gastrointestinal hypomotility and orthostatic hypotension. ... [A185747] However, its promiscuity toward the muscarinic and adrenergic receptors can result in other ... Despite its effectiveness in treating both positive and negative symptoms of schizophrenia, clozapine …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Description: … side effects, notably gastrointestinal hypomotility and orthostatic hypotension. ... [A185747] However, its promiscuity toward the muscarinic and adrenergic receptors can result in other ... Despite its effectiveness in treating both positive and negative symptoms of schizophrenia, clozapine …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Diazepines, Oxazepines, Thiazepines and Oxepines …
Chromium nicotinate
Approved
Experimental
Upadacitinib
Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression. Rheumatoid arthritis is a chronic autoimmune inflammatory disease affecting the peripheral joints. It is characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage damage...
Approved
Investigational
Matched Iupac: … -trifluoroethyl)pyrrolidine-1-carboxamide ... (3S,4R)-3-ethyl-4-{1,5,7,10-tetraazatricyclo[7.3.0.0^{2,6}]dodeca-2(6),3,7,9,11-pentaen-12-yl}-N-(2,2,2 …
Matched Description: … Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic ... and bone destruction, leading to co-morbidities. ... It is characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage damage …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic ... and bone destruction, leading to co-morbidities. ... It is characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage damage …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Ruxolitinib
Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. It is a potent and selective inhibitor of JAK1 and JAK2, which are tyrosine kinases involved in cytokine signalling and hematopoiesis. Myeloproliferative neoplasms, such as myelofibrosis and polycythemia vera, are often characterized by...
Approved
Matched Iupac: … (3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)propanenitrile …
Matched Description: … It is a potent and selective inhibitor of JAK1 and JAK2,[A229698] which are tyrosine kinases involved ... By inhibiting JAK1 and JAK2, ruxolitinib works to block the dysregulated cell signalling pathways and ... in cytokine signalling and hematopoiesis. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents …
Matched Description: … It is a potent and selective inhibitor of JAK1 and JAK2,[A229698] which are tyrosine kinases involved ... By inhibiting JAK1 and JAK2, ruxolitinib works to block the dysregulated cell signalling pathways and ... in cytokine signalling and hematopoiesis. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents …
Citalopram
Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Iupac: … 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile …
Matched Description: … It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing ... and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors. ... A14720] Citalopram enhances serotonergic transmission through the inhibition of serotonin reuptake, and …
Matched Description: … It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing ... and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors. ... A14720] Citalopram enhances serotonergic transmission through the inhibition of serotonin reuptake, and …
Fenofibric acid
Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile, prodrug ,fenofibrate, and other conjugated compounds...
Approved
Matched Iupac: … 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid …
Matched Description: … for improved solubility, gastrointestinal absorption, and bioavailability, and more convenient administration ... acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and ... ], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed …
Matched Description: … for improved solubility, gastrointestinal absorption, and bioavailability, and more convenient administration ... acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and ... ], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed …
Insulin human
Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin. Typically prescribed for the management of diabetes mellitus,...
Approved
Investigational
Matched Synonyms: … Human insulin ... Insulin human ... Insulin (human) …
Matched Name: … Insulin human …
Matched Description: … of hyperglycemia caused by Type 1 and Type 2 Diabetes. ... Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin ... Human Insulin is a 51 residue peptide hormone produced by recombinant DNA technology by inserting the …
Matched Mixtures name: … Humulin 30/70 (insulin Human Biosynth Inj) ... Humulin 30/70 (insulin Human Biosynth Inj) ... MIXTARD 30 HM 100 IU/ML ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET …
Matched Salts name: … Insulin human zinc suspension …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin (human) ... insulin (human) ... insulin (human) …
Matched Products: … HUMULIN R 100 IU/ML ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... HUMULIN N (NPH) 100 IU/ML SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... ACTRAPID HM 100 IU/ML ENJEKSİYONLUK ÇÖZELTI İÇEREN FLAKON, 1 ADET …
Matched Name: … Insulin human …
Matched Description: … of hyperglycemia caused by Type 1 and Type 2 Diabetes. ... Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin ... Human Insulin is a 51 residue peptide hormone produced by recombinant DNA technology by inserting the …
Matched Mixtures name: … Humulin 30/70 (insulin Human Biosynth Inj) ... Humulin 30/70 (insulin Human Biosynth Inj) ... MIXTARD 30 HM 100 IU/ML ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET …
Matched Salts name: … Insulin human zinc suspension …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin (human) ... insulin (human) ... insulin (human) …
Matched Products: … HUMULIN R 100 IU/ML ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... HUMULIN N (NPH) 100 IU/ML SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... ACTRAPID HM 100 IU/ML ENJEKSİYONLUK ÇÖZELTI İÇEREN FLAKON, 1 ADET …
Antihemophilic factor human
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Synonyms: … F8 protein, human ... factor VIII, human ... Factor VIII (human) …
Matched Name: … Antihemophilic factor human …
Matched Description: … ], which is produced by recombinant DNA technology and is identical in sequence to endogenously produced ... plasma, rather than being produced through recombinant DNA technology. ... Antihemophilic factor human is approved by the Food and Drug Administration for use in hemophilia A ( …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... BERIPLAST-P COMBI SET 1 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Human Antihemophilic Factors ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000 IU …
Matched Name: … Antihemophilic factor human …
Matched Description: … ], which is produced by recombinant DNA technology and is identical in sequence to endogenously produced ... plasma, rather than being produced through recombinant DNA technology. ... Antihemophilic factor human is approved by the Food and Drug Administration for use in hemophilia A ( …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... BERIPLAST-P COMBI SET 1 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Human Antihemophilic Factors ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000 IU …
Mecasermin
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Synonyms: … RH-OLIGOPEPTIDE-2 ... VEXXON-IGF-1 ... INSULIN-LIKE GROWTH FACTOR 1 …
Matched Description: … Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label ... gene for human IGF-1. ... IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a …
Matched Categories: … Recombinant Human Insulin-like Growth Factor-1 ... Human Insulin-like Growth Factor Analogs ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins …
Matched Description: … Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label ... gene for human IGF-1. ... IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a …
Matched Categories: … Recombinant Human Insulin-like Growth Factor-1 ... Human Insulin-like Growth Factor Analogs ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins …
Thrombin alfa
Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human thrombin. Thrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically...
Approved
Matched Synonyms: … Thrombin (synthetic human) ... Human Thrombin (recombinant, glycosylated) …
Matched Description: … Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically ... The thrombin alfa product ultimate comes from recombinant human prethrombin-1 [L2079]. ... Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Description: … Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically ... The thrombin alfa product ultimate comes from recombinant human prethrombin-1 [L2079]. ... Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Teduglutide
Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide...
Approved
Matched Synonyms: … Glucagon-like peptide II (2-glycine) (human) ... Gly(2)-GLP-2 ... (Gly2)GLP-2 …
Matched Description: … DNA technology. ... It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant ... Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. …
Matched Categories: … Glucagon-like Peptide-2 (GLP-2) Agonists ... GLP-2 Analog ... Glucagon-Like Peptide 2 ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Description: … DNA technology. ... It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant ... Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. …
Matched Categories: … Glucagon-like Peptide-2 (GLP-2) Agonists ... GLP-2 Analog ... Glucagon-Like Peptide 2 ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Vestronidase alfa
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. ... sequence as human beta-glucuronidase (GUS) [FDA Label]. ... Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. ... sequence as human beta-glucuronidase (GUS) [FDA Label]. ... Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Insulin detemir
Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Synonyms: … Insulin,detemir,human …
Matched Description: … and Type 2 Diabetes. ... typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... [A2358, A2359, A2360, A44] Insulin detemir is produced using recombinant DNA technology in yeast cells …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … and Type 2 Diabetes. ... typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... [A2358, A2359, A2360, A44] Insulin detemir is produced using recombinant DNA technology in yeast cells …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Cidofovir
Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] It was manufactured by Gilead and initially approved by the FDA in 1996, but has since been discontinued.
Approved
Matched Synonyms: … (S)-(3-(4-amino-2-Oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid ... ({[(S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid ... [(S)-2-(4-Amino-2-oxo-2H-pyrimidin-1-yl)-1-hydroxymethyl-ethoxymethyl]-phosphonic acid …
Matched Iupac: … ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid …
Matched Description: … It suppresses CMV replication through selective inhibition of viral DNA synthesis. ... [FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since …
Matched Salts cas: … 149394-66-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … SIDOVIS 375 MG/5 ML KONSANTRE INFÜZYONLUK ÇÖZELTI IÇEREN FLAKON, 1 ADET …
Matched Iupac: … ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid …
Matched Description: … It suppresses CMV replication through selective inhibition of viral DNA synthesis. ... [FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since …
Matched Salts cas: … 149394-66-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … SIDOVIS 375 MG/5 ML KONSANTRE INFÜZYONLUK ÇÖZELTI IÇEREN FLAKON, 1 ADET …
Spesolimab
Spesolimab is an interleukin-36 (IL-36) receptor antagonist. It is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. The biosimilar of the drug, spesolimab-sbzo, was first approved by the FDA in September 2022 to treat generalized pustular psoriasis flares. Spesolimab...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 36 receptor) (humanized monoclonal BI 655130 gamma1-chain) …
Matched Description: … monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA ... A252220, A252225] Spesolimab received recommendations from the EMA's Committee for Medicinal Products for Human ... Use (CHMP) to be granted marketing authorization in October 2022 and was finally approved in December …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Spevigo 450 mg/7,5 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 2 ADET …
Matched Description: … monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA ... A252220, A252225] Spesolimab received recommendations from the EMA's Committee for Medicinal Products for Human ... Use (CHMP) to be granted marketing authorization in October 2022 and was finally approved in December …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Spevigo 450 mg/7,5 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 2 ADET …
Delavirdine
A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
Approved
Matched Synonyms: … (N-[2-[4-[3-(1-methylethylamino)pyridin-2-yl]piperazin-1-yl]carbonyl-1H-indol-5-yl] methanesulfonamide ... 2-(4-(5-methanesulfonamido-1H-indol-2-ylcarbonyl)-1-piperazinyl)-N-(1-methylethyl)-3-pyridinamine ... 1-(3-((1-methylethyl)amino)-2-pyridinyl)-4-((5-((methylsulfonyl)amino)-1H-indol-2-yl)carbonyl)piperazine …
Matched Iupac: … N-[2-(4-{3-[(propan-2-yl)amino]pyridin-2-yl}piperazine-1-carbonyl)-1H-indol-5-yl]methanesulfonamide …
Matched Description: … A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1. …
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … N-[2-(4-{3-[(propan-2-yl)amino]pyridin-2-yl}piperazine-1-carbonyl)-1H-indol-5-yl]methanesulfonamide …
Matched Description: … A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1. …
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 1-Ring …
Eftrenonacog alfa
Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H)...
Approved
Investigational
Matched Synonyms: … Recombinant human coagulation factor IX, FC Fusion protein …
Matched Description: … (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H ... It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region ... It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Description: … (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H ... It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region ... It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Erythropoietin
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Synonyms: … Erythropoietin (recombinant human) ... Erythropoietin (human, recombinant) …
Matched Description: … the human erythropoietin gene has been introduced. ... a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using recombinant DNA ... and displays equivalent clinical efficacy, potency, and purity to the reference product [A7504]. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Products: … ./1 ML ... ./1 ML ... BINOCRIT 2000 IU/1 ML SC/IV ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Matched Description: … the human erythropoietin gene has been introduced. ... a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using recombinant DNA ... and displays equivalent clinical efficacy, potency, and purity to the reference product [A7504]. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Products: … ./1 ML ... ./1 ML ... BINOCRIT 2000 IU/1 ML SC/IV ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
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