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Displaying drugs 7476 - 7500 of 13048 in total
M1-c6v1 is a recombinant oncolytic virus.
Investigational
MK-0731 is a kinesin spindle protein inhibitor and antineoplastic agent.
Experimental
Matched Iupac: … (2S)-4-(2,5-difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2- ... phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
RO-5045337 is under investigation in clinical trial NCT01164033 (A Study of RO5045337 in Patients With Solid Tumors).
Investigational
Matched Iupac: … 1-[(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole ... -1-carbonyl]-4-(3-methanesulfonylpropyl)piperazine …
Experimental
Matched Synonyms: … (3E)-4-(2-Hydroxyphenyl)-2-oxobut-3-enoate ... 4-(2-Hydroxyphenyl)-2-oxo-3-butenoic acid ... (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoic acid …
Matched Iupac: … (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoic acid …
Experimental
Matched Name: … (4-{4-[(TERT-BUTOXYCARBONYL)AMINO]-2,2-BIS(ETHOXYCARBONYL)BUTYL}PHENYL)SULFAMIC ACID …
Matched Iupac: … N-{4-[2-(2-{[(tert-butoxy)carbonyl]amino}ethyl)-3-ethoxy-2-(ethoxycarbonyl)-3-oxopropyl]phenyl}sulfamic …
Experimental
Matched Name: … 5-(4-FLUOROPHENYL)-3-{[(4-METHYLPHENYL)SULFONYL]AMINO}THIOPHENE-2-CARBOXYLIC ACID …
Matched Iupac: … 5-(4-fluorophenyl)-3-(4-methylbenzenesulfonamido)thiophene-2-carboxylic acid …
Uprifosbuvir is under investigation in clinical trial NCT02332707 (Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Genotype (GT)1 and GT2 Infection (MK-3682-011)).
Investigational
Matched Iupac: … propan-2-yl (2R)-2-{[(R)-{[(2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Genotype (GT)1
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … [4-(1,3,2-Dioxaborolan-2-Yloxy)Methyl]Benzamidine …
Matched Iupac: … [amino({4-[(1,3,2-dioxaborolan-2-yloxy)methyl]phenyl})methylidene]azanium …
PIK3CA is under investigation in clinical trial NCT02957266 (Cervical Cancer Radiotherapy by Use of VMAT, Individualized Polyradiosensitization and Interstitial Brachytherapy).
Investigational
Experimental
Matched Name: … 5'-ACETYL-4-{[(2,4-DIMETHYLPHENYL)SULFONYL]AMINO}-2,2'-BITHIOPHENE-5-CARBOXYLIC ACID …
Matched Iupac: … 5'-acetyl-4-(2,4-dimethylbenzenesulfonamido)-[2,2'-bithiophene]-5-carboxylic acid …
Experimental
Matched Name: … Nicotinamide-adenine-dinucleotide-5-hydroxy-4-oxonorvaline …
Matched Iupac: … 4-[(1S,4S)-4-amino-4-carboxy-1-hydroxy-2-oxobutyl]-1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-amino ... phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1- …
Experimental
Matched Iupac: … butanoyl-6-[(3-butanoyl-2,4-dihydroxy-6-methoxyphenyl)methyl]-3,5-dihydroxy-4,4-dimethylcyclohexa-2,5-dien-1- …
Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis).
Investigational
SGS-742 has been used in trials studying the treatment of Seizures and Metabolic Disease.
Investigational
SPP301 (Avosentan) is a potent and highly selective ET[A] receptor blocker and is clinically investigated in diabetic nephropathy. This study was designed to evaluate whether avosentan influences the pharmacokinetics of steroid oral contraceptives.
Investigational
SRP 299 is a preparation of killed Mycobacterium vaccae that has been tested in uses related to inhibiting periodontal disease, in treating asthma and in treating eczema, itching and inflammation. Mycobacterium vaccae is a non-pathogenic, saprophytic bacteria whose antigens can be used to induce peripheral immune activation through the activity...
Investigational
SP-8203 has been used in trials studying the treatment of Ischemic Stroke.
Investigational
Matched Iupac: … N-[3-(2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)propyl]-N-(4-{[3-(2,4-dioxo-1,2,3,4-tetrahydroquinazolin …
Investigational
Matched Synonyms: … S 38093 ... S-38093 free base …
Matched Name: … S-38093 …
Matched Iupac: … 4-(3-{octahydrocyclopenta[c]pyrrol-2-yl}propoxy)benzamide …
SIG-007 is a gene therapy that consists of cells that are genetically modified with a non-viral vector to express human alpha-galactosidase A. Developed by Sigilon Therapeutics, t is being investigated for the treatment of Fabry Disease.
Investigational
SER-287 comprises healthy microbiome-derived Gram positive bacterial spores.
Investigational
STP-707 is a small interfering RNA (siRNA) targeting TGF-Beta1 and COX-2 mRNA.
Investigational
SIG-207 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral vector to express Human alpha-galactosidase A (alpha-Gal A), encapsulated within two-layer modified alginate spheres
Investigational
Displaying drugs 7476 - 7500 of 13048 in total