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Displaying drugs 7651 - 7675 of 8410 in total
Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic Therapy.
Investigational
Matched Synonyms: … N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide ... N-[[4-[(2-aminoanilino)-oxomethyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester …
Matched Iupac: … (pyridin-3-yl)methyl N-({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)carbamate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tenocyclidine (TCP, thienyl cyclohexylpiperidine) is a dissociative anesthetic drug with stimulant and hallucinogenic effects. It is more potent than phencyclidine and hence, this drug was classified under the schedule 1 in 1970.
Experimental
Illicit
Investigational
Matched Synonyms: … 1-[1-(thiophen-2-yl)cyclohexyl]piperidine …
Matched Iupac: … 1-[1-(thiophen-2-yl)cyclohexyl]piperidine …
Matched Description: … It is more potent than phencyclidine and hence, this drug was classified under the schedule 1 in 1970 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Oxabolone cipionate is the C17β cypionate ester and a prodrug of DB01500. A synthetic anabolic-androgenic (AAS) steroid, it is a derivative of 19-nortestosterone (nandrolone). It is considered as a performance enhancing drug thus is prohibited from use in sports.
Experimental
Matched Iupac: … (1S,2R,10R,11S,14S,15S)-6-hydroxy-15-methyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-14-yl 3-cyclopentylpropanoate …
Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)).
Investigational
Matched Synonyms: … Immunoglobulin g4 (234-proline), anti-(human protein garp-transforming growth factor .beta.1 complex) …
Faldaprevir has been investigated for the treatment of Chronic Hepatitis C.
Investigational
Matched Iupac: … (1R,2S)-1-[(2S,4R)-4-({8-bromo-7-methoxy-2-[2-(2-methylpropanamido)-1,3-thiazol-4-yl]quinolin-4-yl}oxy ... -1-carboxylic acid ... )-1-[(2S)-2-{[(cyclopentyloxy)carbonyl]amino}-3,3-dimethylbutanoyl]pyrrolidine-2-amido]-2-ethenylcyclopropane …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … 4-{[(1S,3aS,3bS,9aR,9bS,10R,11aS)-1-acetyl-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH, …
Gusacitinib is under investigation in clinical trial NCT02550678 (A Study of the Efficacy and Safety of ASN-002 in Adult Patients With Low-risk Nodular Basal Cell Carcinoma).
Investigational
Matched Synonyms: … 1-(4-(4-(4-HYDROXY-PIPERIDIN-1-YL)-PHENYLAMINO)-5-OXO-5,6-DIHYDRO-PYRIMIDO(4,5-D)PYRIDAZIN-2-YL)-PIPERIDIN …
Matched Iupac: … 2-[1-(4-{[4-(4-hydroxypiperidin-1-yl)phenyl]amino}-5-oxo-5H,6H-pyrimido[4,5-d]pyridazin-2-yl)piperidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Iupac: … 4-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamido]benzoic …
Experimental
Matched Iupac: … 2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione …
Experimental
Matched Name: … 4-Sulfonamide-[1-(4-Aminobutane)]Benzamide …
Thymalfasin is a chemically synthesized version of thymosin alpha 1 that is identical to human thymosin alpha 1. Thymosin alpha 1 is an acetylated polypeptide. Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. It is also used to boost the...
Investigational
Matched Description: … alpha 1. ... Thymosin alpha 1 is an acetylated polypeptide. ... Thymalfasin is a chemically synthesized version of thymosin alpha 1 that is identical to human thymosin …
Experimental
Matched Synonyms: … (S)-2-amino-3-phenylpropanamide …
Matched Iupac: … (2S)-2-amino-3-phenylpropanamide …
NUC-7738 is under investigation in clinical trial NCT03829254 (A Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma).
Investigational
Matched Synonyms: … L-Alanine, N-(3′-deoxy-P-phenyl-5′-adenylyl)-, phenylmethyl ester (ACI) …
Investigational
Matched Synonyms: … Peptide t amide, 1(d-ala) …
Matched Iupac: … ]-3-hydroxybutanamido]-3-hydroxybutanamido]-N-[(1S)-1-{[(1S,2R)-1-carbamoyl-2-hydroxypropyl]carbamoyl ... (2S)-2-[(2S,3R)-2-[(2S,3R)-2-[(2S,3R)-2-[(2S)-2-[(2R)-2-aminopropanamido]-3-hydroxypropanamido]-3-hydroxybutanamido …
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(hepatitis b surface antigen) (human monoclonal gc1102 .gamma.1-chain), disulfide …
AMPA is a specific agonist for the AMPA receptor.
Experimental
Matched Synonyms: … (S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid …
Matched Iupac: … (2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl)propanoic acid …
Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. In 1982, it was approved in Japan and South Korea for the management of bronchial asthma. Indications for keloid and hypertrophic scar were added in 1993. It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis...
Investigational
Matched Iupac: … 2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enamido]benzoic acid …
Also known as protocatechuic aldehyde, protocatechualdehyde is a naturally-occuring phenolic aldehyde that is found in barley, green cavendish bananas, grapevine leaves and root of the herb S. miltiorrhiza . Protocatechualdehyde possesses antiproliferative and pro-apoptotic properties against human breast cancer cells and colorectal cancer cells by reducing the expression of pro-oncogenes...
Experimental
The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Synonyms: … 2'-C-methylcytidine 3'-O-L-valinyl ester …
Matched Iupac: … 3-yl (2S)-2-amino-3-methylbutanoate ... (2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan- …
Matched Description: … The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … 2-(2-{2-[(BIPHENYL-4-YLMETHYL)-AMINO]-3-MERCAPTO-PENTANOYLAMINO}-ACETYLAMINO)-3-METHYL-BUTYRIC ACID METHYL …
Matched Iupac: … methyl (2S)-2-{2-[(2R)-2-[({[1,1'-biphenyl]-4-yl}methyl)amino]-3-sulfanylpropanamido]acetamido}-3-methylbutanoate …
Experimental
Matched Iupac: … [(3R)-3-[(2-{[2-(heptanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy]phosphinic …
Experimental
Matched Iupac: … (2S)-2-({[(1R)-1-[(2S)-2-{[(benzyloxy)carbonyl]amino}propanamido]ethyl](hydroxy)phosphoryl}oxy)-3-phenylpropanoic …
Displaying drugs 7651 - 7675 of 8410 in total