Displaying drugs 7701 - 7725 of 8194 in total
Indoximod
Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.
Investigational
Matched Synonyms: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid …
Matched Iupac: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid …
Matched Iupac: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid …
Fluoromisonidazole F-18
Fluoromisonidazole F-18 is under investigation in clinical trial NCT01507428 (Study of Positron Emission Tomography and Computed Tomography in Guiding Radiation Therapy in Patients With Stage III Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … 1-(2-Nitro-Imidazolyl)-3-[18F]Fluoro-2-Propanol ... 1H-1-(3-[18F]Fluoro-2-Hydroxypropyl-2-Nitroimidazole 18F …
Matched Iupac: … 1-(¹⁸F)fluoro-3-(2-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Iupac: … 1-(¹⁸F)fluoro-3-(2-nitro-1H-imidazol-1-yl)propan-2-ol …
Tanespimycin
Tanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor of heat shock protein 90 (HSP90). It is developed for the treatment of several types of cancer, solid tumors or chronic myelogenous leukemia.
Investigational
Matched Iupac: … tetramethyl-20,22-dioxo-19-[(prop-2-en-1-yl)amino]-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18-hexaen-9- …
Sabarubicin
Sabarubicin has been used in trials studying the treatment of Prostate Cancer, Testicular Germ Cell Tumor, and Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Iupac: … (7S,9S)-7-{[(2R,4S,5S,6S)-5-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan ... -2-yl]oxy}-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-5,7,8,9,10,12-hexahydrotetracene-5,12-dione …
Motuporin
Motuporin is a toxin isolated from the marine sponge Thenonella swinhoie grey.
Experimental
Matched Iupac: … 3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dien-1-yl]-1,6,13-trimethyl-3,7,10,14,19-pentaoxo-9- …
Propagermanium
Investigational
Matched Synonyms: … 3-[[2-carboxyethyl(oxo)germyl]oxy-oxogermyl]propanoic acid …
(S)-2-(MERCAPTOMETHYL)-5-PHENYLPENTANOIC ACID
Experimental
Matched Name: … (S)-2-(MERCAPTOMETHYL)-5-PHENYLPENTANOIC ACID …
Matched Iupac: … (2S)-5-phenyl-2-(sulfanylmethyl)pentanoic acid …
Matched Iupac: … (2S)-5-phenyl-2-(sulfanylmethyl)pentanoic acid …
Dextrorphan
Experimental
Matched Synonyms: … (+)-N-methylmorphinan-3-ol ... d-3-hydroxy-N-methylmorphinan …
Matched Iupac: … (1S,9S,10S)-17-methyl-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-trien-4-ol …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Iupac: … (1S,9S,10S)-17-methyl-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-trien-4-ol …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Nendratareotide uzatansine
Nendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated to the cytotoxin mertansine.
Investigational
Matched Synonyms: … Peptide-drug conjugate combining [(Tyr3,Cys8) octreotate amide] and N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl …
Laruparetigene zovaparvovec
Investigational
Obinepitide
Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which normally are released during a meal. These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from the GI-tract to the CNS. In obinepitide,...
Investigational
Matched Iupac: … ]amino}-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxyethylidene] ... -hydroxypropylidene]amino}-3-hydroxybutanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-4-{[(1S)-1-{ ... methylpentylidene]amino}-4-carboxybutanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxy-3-methylbutylidene ... amino}-3-carboxy-1-hydroxypropylidene]amino}-1-hydroxy-3-(C-hydroxycarbonimidoyl)propylidene]amino}-1 ... 1S)-4-carbamimidamido-1-{[(1S)-1-{[(1S,2S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S,2R)-1-{[(1S)-4-carbamimidamido …
Odronextamab
Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody currently evaluated for the treatment of relapsed/refractory (R/R) B-Cell non-Hodgkin lymphoma (NHL).[A254187,A254197] Preliminary studies have shown that in patients with R/R NHL, the use of odronextamab does not lead to the development of neurologic toxicity; however, it can...
Investigational
Vobramitamab duocarmazine
Vobramitamab duocarmazine is under investigation in clinical trial NCT05551117 (A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors).
Investigational
Lomvastomig
Lomvastomig is under investigation in clinical trial NCT04785820 (A Study of Lomvastomig (RO7121661) and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus).
Investigational
Matched Synonyms: … Anti-pd-1/tim-3 bispecific antibody ro7121661 …
Relmacabtagene autoleucel
Investigational
6-(Oxalyl-Amino)-1h-Indole-5-Carboxylic Acid
Experimental
Matched Name: … 6-(Oxalyl-Amino)-1h-Indole-5-Carboxylic Acid …
Matched Iupac: … 6-(carboxyformamido)-1H-indole-5-carboxylic acid …
Matched Iupac: … 6-(carboxyformamido)-1H-indole-5-carboxylic acid …
(1R)-2-[(CYANOMETHYL)AMINO]-1-({[2-(DIFLUOROMETHOXY)BENZYL]SULFONYL}METHYL)-2-OXOETHYL MORPHOLINE-4-CARBOXYLATE
Experimental
Matched Name: … (1R)-2-[(CYANOMETHYL)AMINO]-1-({[2-(DIFLUOROMETHOXY)BENZYL]SULFONYL}METHYL)-2-OXOETHYL MORPHOLINE-4-CARBOXYLATE …
Matched Iupac: … (1R)-1-[(cyanomethyl)carbamoyl]-2-{[2-(difluoromethoxy)phenyl]methanesulfonyl}ethyl morpholine-4-carboxylate …
Matched Iupac: … (1R)-1-[(cyanomethyl)carbamoyl]-2-{[2-(difluoromethoxy)phenyl]methanesulfonyl}ethyl morpholine-4-carboxylate …
N-[(1S)-2-{[(1R)-2-(benzyloxy)-1-cyano-1-methylethyl]amino}-1-(cyclohexylmethyl)-2-oxoethyl]morpholine-4-carboxamide
Experimental
Matched Name: … (1S)-2-{[(1R)-2-(benzyloxy)-1-cyano-1-methylethyl]amino}-1-(cyclohexylmethyl)-2-oxoethyl]morpholine-4- …
Matched Iupac: … (2S)-N-[(1R)-2-(benzyloxy)-1-cyano-1-methylethyl]-3-cyclohexyl-2-[(morpholine-4-carbonyl)amino]propanamide …
Matched Iupac: … (2S)-N-[(1R)-2-(benzyloxy)-1-cyano-1-methylethyl]-3-cyclohexyl-2-[(morpholine-4-carbonyl)amino]propanamide …
3-(BUTYLSULPHONYL)-PROPANOIC ACID
Experimental
Matched Name: … 3-(BUTYLSULPHONYL)-PROPANOIC ACID …
Matched Iupac: … 3-(butane-1-sulfonyl)propanoic acid …
Matched Iupac: … 3-(butane-1-sulfonyl)propanoic acid …
24-Homo-1,25-dihydroxyvitamin D3
24-Homo-1,25-dihydroxyvitamin D3 is a novel vitamin D analogue.
Experimental
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-7-hydroxy-7-methyloctan-2-yl]-7a-methyl-octahydro-1H-inden-4 ... -ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol …
3-O-Methylfructose in Linear Form
Experimental
Matched Name: … 3-O-Methylfructose in Linear Form …
Matched Iupac: … (3S,4R,5R)-1,4,5,6-tetrahydroxy-3-methoxyhexan-2-one …
Matched Iupac: … (3S,4R,5R)-1,4,5,6-tetrahydroxy-3-methoxyhexan-2-one …
Displaying drugs 7701 - 7725 of 8194 in total