Displaying drugs 776 - 800 of 2720 in total
Satralizumab
Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Synonyms: … Humanised anti-IL-6 receptor monoclonal antibody …
Matched Description: … [A218551] Some of the pro-inflammatory mechanisms involved in NMOSD are thought to be mediated, at least ... [A218551] It received subsequent approvals in Switzerland and Japan,[A218551] and was approved for use ... 6) receptors, similar to [tocilizumab], which is produced in Chinese hamster ovary cells and based on …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … [A218551] Some of the pro-inflammatory mechanisms involved in NMOSD are thought to be mediated, at least ... [A218551] It received subsequent approvals in Switzerland and Japan,[A218551] and was approved for use ... 6) receptors, similar to [tocilizumab], which is produced in Chinese hamster ovary cells and based on …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
A166
A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable valine citrulline linker.
Investigational
Matched Synonyms: … Recombinant humanized IgG1 anti-HER2 monoclonal antibody conjugated to Duostatin-5 …
Matched Description: … A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) ... site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable …
Matched Description: … A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) ... site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable …
Nitarsone
Nitarsone is an organoarsenic compound. It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing blackhead disease. It is marketed as Histostat by Zoetis, a publicly traded subsidiary of Pfizer.
Vet approved
Matched Synonyms: … (p-nitrophenyl)arsonic acid ... 4-nitrobenzenearsonic acid ... 4-nitrophenylarsonic acid …
Matched Iupac: … (4-nitrophenyl)arsonic acid …
Matched Description: … It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing …
Matched Iupac: … (4-nitrophenyl)arsonic acid …
Matched Description: … It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing …
Cyclohexanepropanoic acid
Experimental
Matched Synonyms: … 3-Cyclohexanepropionic acid ... 3-Cyclohexylpropanoic acid ... 3-Cyclohexylpropionic acid …
Matched Name: … Cyclohexanepropanoic acid …
Matched Iupac: … 3-cyclohexylpropanoic acid …
Matched Name: … Cyclohexanepropanoic acid …
Matched Iupac: … 3-cyclohexylpropanoic acid …
Salicylamide O-acetic acid
Experimental
Matched Synonyms: … Salamidacetic acid ... Salicylamide-2-acetic acid ... 2-Carbamoylphenoxyacetic acid …
Matched Name: … Salicylamide O-acetic acid …
Matched Iupac: … 2-(2-carbamoylphenoxy)acetic acid …
Matched Name: … Salicylamide O-acetic acid …
Matched Iupac: … 2-(2-carbamoylphenoxy)acetic acid …
Caprylhydroxamic acid
Experimental
Matched Synonyms: … Caprylohydroxamic acid ... Octanohydroxamic acid ... Octanoylhydroxamic acid …
Matched Name: … Caprylhydroxamic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Matched Name: … Caprylhydroxamic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
3-phenylpropionic acid
Experimental
Matched Synonyms: … Hydrocinnamic acid ... 3-phenyl-propionic acid ... 3-phenylpropanoic acid …
Matched Name: … 3-phenylpropionic acid …
Matched Iupac: … 3-phenylpropanoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … 3-phenylpropionic acid …
Matched Iupac: … 3-phenylpropanoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
L-2-aminopimelic acid
Experimental
Matched Synonyms: … 2-Aminopimelic acid ... L-α-aminopimelic acid ... L-alpha-Aminopimelic acid …
Matched Name: … L-2-aminopimelic acid …
Matched Iupac: … (2S)-2-aminoheptanedioic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … L-2-aminopimelic acid …
Matched Iupac: … (2S)-2-aminoheptanedioic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
(S)-3-phenyllactic acid
Experimental
Matched Synonyms: … L-3-phenyllactic acid ... L-β-phenyllactic acid ... L-(−)-3-phenyllactic acid …
Matched Name: … (S)-3-phenyllactic acid …
Matched Iupac: … (2S)-2-hydroxy-3-phenylpropanoic acid …
Matched Name: … (S)-3-phenyllactic acid …
Matched Iupac: … (2S)-2-hydroxy-3-phenylpropanoic acid …
Pidolic acid
Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various chemical pathways [A32991, L2729]. Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism...
Approved
Investigational
Matched Synonyms: … Glutimic acid ... Pidolic acid ... Pyroglutamic acid …
Matched Name: … Pidolic acid …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Description: … Pidolic acid, in general, is found in large quantities in brain tissue and other tissues in bound form ... or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various ... Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically …
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids ... Imino Acids …
Matched Name: … Pidolic acid …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Description: … Pidolic acid, in general, is found in large quantities in brain tissue and other tissues in bound form ... or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various ... Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically …
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids ... Imino Acids …
L-tartaric acid
Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.
Experimental
Matched Synonyms: … (+)-Tartaric acid ... Tartaric acid ... (+)-L-tartaric acid …
Matched Name: … L-tartaric acid …
Matched Iupac: … (2R,3R)-2,3-dihydroxybutanedioic acid …
Matched Description: … , and is a dihydroxyl derivative of succinic acid. ... in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics ... Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … L-tartaric acid …
Matched Iupac: … (2R,3R)-2,3-dihydroxybutanedioic acid …
Matched Description: … , and is a dihydroxyl derivative of succinic acid. ... in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics ... Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids ... Dicarboxylic Acids …
AOC 1001
AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA (siRNA).
Investigational
Matched Synonyms: … an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting ... , effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA ( …
Matched Description: … AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 ... (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering …
Matched Description: … AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 ... (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering …
Norvaline
Norvaline is an isomer of the more common amino acid valine.
Experimental
Matched Synonyms: … 2-Aminovaleric acid ... 2-Aminopentanoic acid ... L-2-Aminovaleric acid …
Matched Iupac: … (2S)-2-aminopentanoic acid …
Matched Description: … Norvaline is an isomer of the more common amino acid valine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Branched-Chain …
Matched Iupac: … (2S)-2-aminopentanoic acid …
Matched Description: … Norvaline is an isomer of the more common amino acid valine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Branched-Chain …
Oxaloacetic acid
Investigational
Matched Synonyms: … Oxalacetic acid ... Ketosuccinic acid ... Oxosuccinic acid …
Matched Name: … Oxaloacetic acid …
Matched Iupac: … 2-oxobutanedioic acid …
Matched Categories: … Keto Acids ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … Oxaloacetic acid …
Matched Iupac: … 2-oxobutanedioic acid …
Matched Categories: … Keto Acids ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
alpha-Linolenic acid
Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Approved
Investigational
Nutraceutical
Matched Synonyms: … Linolenic acid ... α-linolenic acid ... (9,12,15)-linolenic acid …
Matched Name: … alpha-Linolenic acid …
Matched Iupac: … (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid …
Matched Description: … It is a component of many common vegetable oils and is important to human nutrition. ... Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. …
Matched Categories: … Fatty Acids ... Linolenic Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Matched Name: … alpha-Linolenic acid …
Matched Iupac: … (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid …
Matched Description: … It is a component of many common vegetable oils and is important to human nutrition. ... Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. …
Matched Categories: … Fatty Acids ... Linolenic Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Evofosfamide
TH-302 is a novel cancer therapeutic specifically activated under the low oxygen or "hypoxic" conditions typical of solid tumor cancer cells. TH-302 is a nitroimidazole-linked prodrug of a brominated derivative of an isophosphoramide mustard previously used in cancer drugs such as ifosfamide, cyclophosphamide, and glufosfamide. TH-302 has been shown, in...
Investigational
Matched Synonyms: … (1-methyl-2-nitro-1H-imidazol-5-YL)methyl N,N'-bis(2-bromoethyl)diamidophosphate ... (1-methyl-2-nitro-1H-imidazole-5-yl)methyl N,N'-bis(2-bromoethyl) diamidophosphate …
Matched Iupac: … (2-bromoethyl)({[(2-bromoethyl)amino][(1-methyl-2-nitro-1H-imidazol-5-yl)methoxy]phosphoryl})amine …
Matched Description: … TH-302 has been shown, in preclinical studies, to be both efficacious and well tolerated. ... of an isophosphoramide mustard previously used in cancer drugs such as ifosfamide, cyclophosphamide, and …
Matched Categories: … Nitro Compounds …
Matched Iupac: … (2-bromoethyl)({[(2-bromoethyl)amino][(1-methyl-2-nitro-1H-imidazol-5-yl)methoxy]phosphoryl})amine …
Matched Description: … TH-302 has been shown, in preclinical studies, to be both efficacious and well tolerated. ... of an isophosphoramide mustard previously used in cancer drugs such as ifosfamide, cyclophosphamide, and …
Matched Categories: … Nitro Compounds …
Iodamide
Iodamide is a contrast medium molecule that is no longer marketed in the United States.
Withdrawn
Matched Synonyms: … Ametriiodic acid ... Ametriodinic acid ... Ametriiodinic acid …
Matched Iupac: … 3-acetamido-5-(acetamidomethyl)-2,4,6-triiodobenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Triiodobenzoic Acids …
Matched Iupac: … 3-acetamido-5-(acetamidomethyl)-2,4,6-triiodobenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Triiodobenzoic Acids …
p-Nitrophenylacetic acid
Experimental
Matched Synonyms: … (4-nitrophenyl)acetic acid ... 4-nitrophenylacetic acid ... 4-nitrobenzeneacetic acid …
Matched Name: … p-Nitrophenylacetic acid …
Matched Iupac: … 2-(4-nitrophenyl)acetic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … p-Nitrophenylacetic acid …
Matched Iupac: … 2-(4-nitrophenyl)acetic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Deoxycholic acid
Deoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that tissue. In April 2015, deoxycholic acid was approved by the FDA for the treatment submental fat to improve...
Approved
Matched Synonyms: … Deoxycholic acid ... Desoxycholic acid ... 7α-deoxycholic acid …
Matched Name: … Deoxycholic acid …
Matched Iupac: … 9bS,11S,11aR)-7,11-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … Deoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and ... appearance and reduce facial fullness or convexity. ... when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics ... Cholic Acids ... deoxycholic acid …
Matched Name: … Deoxycholic acid …
Matched Iupac: … 9bS,11S,11aR)-7,11-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … Deoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and ... appearance and reduce facial fullness or convexity. ... when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics ... Cholic Acids ... deoxycholic acid …
Rivabazumab pegol
Rivabazumab pegol is being investigated as a treatment of Pseudomonas aeruginosa lung infections in patients with cystic fibrosis.
Investigational
Matched Synonyms: … PEGylated recombinant anti-Pseudomonas aeruginosa PcrV Fab' antibody ... KB001-A (AN ANTI-PCRV PEGYLATED MONOCLONAL ANTIBODY FRAGMENT TO THE TYPE III SECRETION SYSTEM OF PSEUDOMONAS ... ANTI-PSEUDOMONAS AERUGINOSA TYPE III SECRETION SYSTEM (TTSS)PCRV PROTEIN, PEGYLATED HUMANIZED MONOCLONAL ANTIBODY …
Domoic Acid
Experimental
Matched Synonyms: … L-domoic acid ... (-)-domoic acid …
Matched Name: … Domoic Acid …
Matched Iupac: … 3S,4S)-4-[(2Z,4E,6R)-6-carboxy-6-methylhexa-2,4-dien-2-yl]-3-(carboxymethyl)pyrrolidine-2-carboxylic acid …
Matched Name: … Domoic Acid …
Matched Iupac: … 3S,4S)-4-[(2Z,4E,6R)-6-carboxy-6-methylhexa-2,4-dien-2-yl]-3-(carboxymethyl)pyrrolidine-2-carboxylic acid …
Thiosulfuric acid
Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Synonyms: … Sulfurothioic S-acid ... Monosulfanemonosulfonic acid …
Matched Name: … Thiosulfuric acid …
Matched Description: … Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate ... it is frequently used in conjunction with sodium nitrite (a salt form of [nitrous acid]). ... Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has …
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid …
Matched Categories: … Acids ... Sulfur Acids ... Sulfuric Acids …
Matched Name: … Thiosulfuric acid …
Matched Description: … Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate ... it is frequently used in conjunction with sodium nitrite (a salt form of [nitrous acid]). ... Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has …
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid …
Matched Categories: … Acids ... Sulfur Acids ... Sulfuric Acids …
D-Malic acid
Experimental
Matched Synonyms: … (+)-D-malic acid ... (R)-malic acid ... (R)-2-hydroxybutanedioic acid …
Matched Name: … D-Malic acid …
Matched Iupac: … (2R)-2-hydroxybutanedioic acid …
Matched Name: … D-Malic acid …
Matched Iupac: … (2R)-2-hydroxybutanedioic acid …
Gamolenic acid
Gamolenic acid, or gamma-linolenic acid (γ-Linolenic acid) or GLA, is an essential fatty acid (EFA) comprised of 18 carbon atoms with three double bonds that is most commonly found in human milk and other botanical sources . It is an omega-6 polyunsaturated fatty acid (PUFA) also referred to as 18:3n-6;...
Approved
Investigational
Matched Synonyms: … gamoleic acid ... Gamolenic acid ... γ-linolenic acid …
Matched Name: … Gamolenic acid …
Matched Iupac: … (6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid …
Matched Description: … acid; and cis-6, cis-9, cis-12- octadecatrienoic acid [F27]. ... ] and [DB11238] are rich sources of gamolenic acid. ... Gamolenic acid is also found in some fungal sources and also present naturally in the form of triglycerides …
Matched Categories: … Fatty Acids ... gamolenic acid ... Linolenic Acids ... Fatty Acids, Omega-6 ... Fatty Acids, Essential …
Matched Name: … Gamolenic acid …
Matched Iupac: … (6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid …
Matched Description: … acid; and cis-6, cis-9, cis-12- octadecatrienoic acid [F27]. ... ] and [DB11238] are rich sources of gamolenic acid. ... Gamolenic acid is also found in some fungal sources and also present naturally in the form of triglycerides …
Matched Categories: … Fatty Acids ... gamolenic acid ... Linolenic Acids ... Fatty Acids, Omega-6 ... Fatty Acids, Essential …
Icosapent
Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
Approved
Nutraceutical
Matched Synonyms: … Timnodonic acid ... Icosapentaenoic acid ... Eicosapentaenoic acid …
Matched Iupac: … (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid …
Matched Description: … disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane ... -2 and prostaglandin-2 families. ... It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. …
Matched Mixtures name: … Tricare Prenatal Twist-off DHA Soft Quick Dissolve ... Tricare Prenatal Twist-off DHA Soft Quick Dissolve …
Matched Categories: … Fatty Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Unsaturated …
Matched Iupac: … (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid …
Matched Description: … disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane ... -2 and prostaglandin-2 families. ... It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. …
Matched Mixtures name: … Tricare Prenatal Twist-off DHA Soft Quick Dissolve ... Tricare Prenatal Twist-off DHA Soft Quick Dissolve …
Matched Categories: … Fatty Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Unsaturated …
Displaying drugs 776 - 800 of 2720 in total