Displaying drugs 776 - 800 of 934 in total
NZ-1002
Investigational
Matched Synonyms: … Recombinant human highly phosphorylated alpha-L-iduronidase …
Aldafermin
Aldafermin is under investigation in clinical trial NCT03912532 (Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study in Subjects With Nonalcoholic Steatohepatitis and Stage 2/3 Fibrosis (ALPINE 2/3)).
Investigational
Matched Synonyms: … Engineered variant of recombinant human fibroblast growth factor 19 ... (phe5>met,ser6>arg,ala8>ser,gly9>ser,his11>leu) fibroblast growth factor 19 (human fgf19) (5-194)-peptide …
Matched Description: … Aldafermin is under investigation in clinical trial NCT03912532 (Evaluation of Efficacy, Safety and Tolerability ... Double-blind, Placebo-controlled, Multi-center Study in Subjects With Nonalcoholic Steatohepatitis and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Aldafermin is under investigation in clinical trial NCT03912532 (Evaluation of Efficacy, Safety and Tolerability ... Double-blind, Placebo-controlled, Multi-center Study in Subjects With Nonalcoholic Steatohepatitis and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Galsulfase
Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate...
Approved
Investigational
Matched Synonyms: … N-acetylgalactosamine-4-sulfatase, recombinant human …
Matched Description: … The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation ... Cys53 produces the catalytic amino acid residue Ca-formylglycine, which is required for enzyme activity and ... Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Chondroitinases and Chondroitin Lyases …
Matched Description: … The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation ... Cys53 produces the catalytic amino acid residue Ca-formylglycine, which is required for enzyme activity and ... Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Chondroitinases and Chondroitin Lyases …
Tesamorelin
Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia associated with antiretroviral therapy for HIV infection.
Approved
Investigational
Matched Synonyms: … N-[(3E)-1-oxo-3-hexenyl]Somatoliberin (human pancreatic islet) …
Matched Description: … Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia ... Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Hypothalamic Hormones ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues …
Matched Description: … Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia ... Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Hypothalamic Hormones ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues …
KAb201
Investigational
Matched Synonyms: … Anti-CEA sheep-human chimeric monoclonal antibody labeled w/iodine-131 (KAb201) …
TALL-104
Investigational
Matched Synonyms: … Human major histocompatibility complex (MHC) non-restricted T-cell line 104 …
MBP134
MBP134 is a pan-ebolavirus cocktail comprising two broadly neutralizing human antibodies. It is under investigation for the treatment of Sudan ebolavirus (SUDV).
Investigational
Matched Synonyms: … Two immunoglobulin subclass 1 (IgG1) human monoclonal antibodies that target the Sudan ebolavirus glycoprotein …
Matched Description: … MBP134 is a pan-ebolavirus cocktail comprising two broadly neutralizing human antibodies. …
Matched Description: … MBP134 is a pan-ebolavirus cocktail comprising two broadly neutralizing human antibodies. …
Cantuzumab mertansine
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(mucin canag) (human-mouse monoclonal c242 heavy chain), disulfide with human-mouse ... Immunoglobulin g1, anti-(mucin canag) (human-mouse monoclonal c242 heavy chain), disulphide with human-mouse ... Immunoglobulin g1, anti-(mucin canag) human-mouse monoclonal c242 heavy chain), disulfide with human-mouse …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tipapkinogene sovacivec
Investigational
Matched Synonyms: … DNA (synthetic vaccinia virus strain MVA human papillomavirus-targeted) …
Vitespen
Investigational
Matched Synonyms: … Endoplasmin (human tumor rejection antigen 1) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Priliximab
Investigational
Matched Synonyms: … Chimeric M-T412 (human-murine) IgG monoclonal anti-CD4 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
INZ-701
INZ-701 is an enzyme replacement therapy under development with the intention to be used for the treatment of calcification disorders of the circulatory system, bones, and kidneys.
Investigational
Matched Synonyms: … Recombinant human ectonucleotide pyrophosphatase/phosphodiesterase 1 fused to the Fc fragment of IGG1 …
Matched Description: … intention to be used for the treatment of calcification disorders of the circulatory system, bones, and …
Matched Description: … intention to be used for the treatment of calcification disorders of the circulatory system, bones, and …
PRX-ASL
PRX-ASL is an intracellular enzyme replacement therapy designed to replace the missing or defective enzyme in patients with argininosuccinate lyase deficiency.
Investigational
Matched Synonyms: … Modified messenger ribonucleic acid encoding human argininosuccinate lyase enzyme encapsulated into lipid …
Lactulose
Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic encephalopathy (PSE).[FDA Label,L6199,L6202] Despite being first synthesized in 1929 , investigations regarding its possible use as a laxative for...
Approved
Matched Description: … possible use as a laxative for the treatment of chronic constipation did not occur until the 1960s and ... [L6202]
Nevertheless, although lactulose received formal FDA approval in 1977 and has since become ... List of Essential Medicines as one of the most effective and safe medicines employed in a health system …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Duphalac Fruit 667 mg/ml - Lösung zum Einnehmen …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Duphalac Fruit 667 mg/ml - Lösung zum Einnehmen …
Somatorelin
Somatorelin has been used in trials studying the treatment of Aging, Elderly, Sleep Disorders, Hormone Deficiency, and Mild Cognitive Impairment.
Investigational
Matched Synonyms: … SOMATOLIBERIN, HUMAN ... SOMATOLIBERIN (HUMAN) ... GROWTH HORMONE-RELEASING FACTOR (HUMAN) …
Matched Description: … been used in trials studying the treatment of Aging, Elderly, Sleep Disorders, Hormone Deficiency, and …
Matched Categories: … Hypothalamic Hormones ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … been used in trials studying the treatment of Aging, Elderly, Sleep Disorders, Hormone Deficiency, and …
Matched Categories: … Hypothalamic Hormones ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Cendakimab
Cendakimab is a recombinant humanized anti-interleukin 13 (IL-13) monoclonal antibody.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1(240-ALANINE, 241-ALANINE), ANTI-(HUMAN INTERLEUKIN 13) (HUMAN-MUS MUSCULUS MONOCLONAL ... HUMANIZED ANTI-HUMAN IL-13 MONOCLONAL ANTIBODY ... RPC4046 .GAMMA.-1), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL RPC4046 .KAPPA.-1, DIMER …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Zamerovimab
Investigational
Matched Synonyms: … .1-chain), disulfide with human-mus musculus clone 1a9 .kappa. ... Immunoglobulin g1, anti-(rabies lyssavirus spike glycoprotein g) (human-mus musculus clone 1a9 .gamma …
Mazorelvimab
Investigational
Matched Synonyms: … .1-chain), disulfide with human-mus musculus clone 2g11 .kappa. ... Immunoglobulin g1, anti-(rabies lyssavirus spike glycoprotein g) (human-mus musculus clone 2g11 .gamma …
Fordadistrogene movaparvovec
Investigational
Matched Synonyms: … PLUS HUMAN MINI-DYSTROPHIN GENE PLUS ADENO-ASSOCIATED VIRUS 9 INVERTED TERMINAL REPEAT FLANKS) ... DNA (RECOMBINANT ADENO-ASSOCIATED VIRUS 9 VECTOR PF-06939926 HUMAN MUSCLE-SPECIFIC ENHANCER/PROMOTER …
Urtoxazumab
Investigational
Matched Synonyms: … -chain), disulfide with human-mouse monoclonal huvtm1.1 .kappa.-chain, dimer ... Immunoglobulin g1, anti-(escherichia coli shiga-like toxin ii b subunit) (human-mouse monoclonal huvtm1.1 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Recifercept
Investigational
Matched Synonyms: … Recombinant human fibroblast growth factor receptor 3 ... Fibroblast growth factor receptor 3 (recombinant human soluble isoform ta-46) ... Human fibroblast growth factor receptor 3 (fgfr-3, cd333) (1-336)-(401-413) fragment (1-349) (soluble …
Inbakicept
Inbakicept is a dimeric human IL-15 receptor α (IL-15Rα) sushi domain/human IgG1 Fc fusion protein. It is one of the active ingredients in Anktiva, a combination product also containing nogapendekin alfa, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA...
Investigational
Matched Synonyms: … CHAIN (HUMAN SUSHI DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT ... INTERLEUKIN 15 RECEPTOR SUBUNIT ALPHA (HUMAN IL15R.ALPHA.) (1-65)-PEPTIDE (SUSHI DOMAIN-CONTAINING) FUSION ... PROTEIN WITH HUMAN IMMUNOGLOBULIN G1 FC FRAGMENT (232 C-TERMINAL RESIDUES) (66-297) (HOMO SAPIENS IGHG1 …
Matched Description: … Inbakicept is a dimeric human IL-15 receptor α (IL-15Rα) sushi domain/human IgG1 Fc fusion protein. ... 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Inbakicept is a dimeric human IL-15 receptor α (IL-15Rα) sushi domain/human IgG1 Fc fusion protein. ... 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cipaglucosidase alfa
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate …
Matched Description: … types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and ... cipaglucosidase alfa be granted marketing authorization for the treatment of Pompe disease,[L45275] and ... Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and ... cipaglucosidase alfa be granted marketing authorization for the treatment of Pompe disease,[L45275] and ... Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Catridecacog
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor) ... Human Factor XIII (A2) homodimer (allele F13A*1B), recombinant DNA origin …
Matched Description: … then isolated, the human form is isolated from pooled human plasma. ... ) include [DB12909], which is a purified endogenous (human) form of coagulation factor XIII. ... and maintenance of hemostasis [A18581]. …
Matched Categories: … Blood and Blood Forming Organs …
Matched Description: … then isolated, the human form is isolated from pooled human plasma. ... ) include [DB12909], which is a purified endogenous (human) form of coagulation factor XIII. ... and maintenance of hemostasis [A18581]. …
Matched Categories: … Blood and Blood Forming Organs …
Displaying drugs 776 - 800 of 934 in total