Displaying drugs 8126 - 8150 of 11562 in total
SB-409513
Experimental
Matched Synonyms: … I-5 …
Matched Iupac: … 2-chloro-5-{[4-(3-chlorophenyl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]amino}benzoic acid …
Matched Iupac: … 2-chloro-5-{[4-(3-chlorophenyl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]amino}benzoic acid …
Disitamab vedotin
Disitamab vedotin is an antibody-drug conjugate drug targeting human epidermal growth factor receptor 2 (HER2). It is currently being investigated for cancers.
Investigational
Apamistamab iodine I-131
Investigational
Theodrenaline
Theodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
Investigational
Matched Iupac: … 7-(2-{[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]amino}ethyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine- …
Cloprednol
Cloprednol is a synthetic glucocorticoid that has been investigated for use in the treatment of asthma. [A31775,A31776]
Experimental
Matched Iupac: … dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6,8-trien-5- …
GT 389-255
Peptimmune’s lead product GT 389-255, is a novel lipase inhibitor and fat binding hydrogel polymer conjugate for the treatment of obesity which has completed single and multiple ascending dose (SAD and MAD) Phase I trials. It is expected to block fat absorption with fewer side effects than currently marketed lipase...
Investigational
TNB-383B
TNB-383B is a CD3 and B-cell maturation antigen T-cell engaging bispecific antibody.
Investigational
ARO-ANG3
ARO-ANG3 is a subcutaneously administered RNA interference (RNAi)-based investigational medicine targeting angiopoietin-like protein 3 (ANGPTL3). It was granted an orphan drug designation for the treatment of homozygous familial hypercholesterolemia (HoFH).
Investigational
Matched Description: … administered RNA interference (RNAi)-based investigational medicine targeting angiopoietin-like protein 3 …
TORL-2-307
TORL-2307 is a humanized immunoglobulin G1 (IgG1) monoclonal antibody (mAb) directed against claudin 18.2 (CLDN18.2) being investigated for the treatment of gastric and pancreatic cancer.
Investigational
Leptazoline D
Leptazoline D is a polar oxazoline from the Cyanobacterium Leptolyngbya sp. Also see Leptazoline A, Leptazoline B, and Leptazoline C.
Experimental
Matched Iupac: … (2S,3S)-N-(1,3-dihydroxypropan-2-yl)-2,3-dihydroxy-3-[(4S,5S)-2-(2-hydroxyphenyl)-5-methyl-4,5-dihydro ... -1,3-oxazol-4-yl]propanamide …
Bucelipase alfa
Bucelipase alfa is under investigation in clinical trial NCT00743483 (Efficacy of Bucelipase Alfa (BSSL) in Patients With Cystic Fibrosis and Pancreatic Insufficiency).
Investigational
Deoxyepinephrine
Sympathomimetic, vasoconstrictor agent.
Experimental
Matched Synonyms: … 1-(3,4-dihydroxyphenyl)-2-methylaminoethane …
NN344
NN344 is a neutral, soluble long-acting human insulin analogue with 24 hour coverage by once daily injection. NN344 has a very flat and predictable action profile. The product is intended for basal insulin treatment of diabetes mellitus.
Investigational
NPI 32101
NPI 32101 possesses both anti-inflammatory and broad spectrum antimicrobial activities. This combination of pharmacological properties may have additional therapeutic uses beyond dermatology.
Investigational
C31G
C31G is a potent broad spectrum antimicrobial agent, effective against gram positive and gram negative bacteria, yeast and fungi.C31G, vaginal gel is developed by Biosyn Inc. and has commenced enrollment in a phase III pivotal clinical trial for the reduction of sexual transmission of human immunodeficiency virus (HIV).
Investigational
ORG-34517
ORG-34517 is currently under investigation by Organon for the treatment of depression. It has potential to treat a number of diseases such as Cushing’s disease, hypertension, diabetes, glaucoma etc, in which the activity of metabolites corticosterone and cortisol is high.
Investigational
Matched Iupac: … (1S,3aS,3bS,10R,11aS)-10-(2H-1,3-benzodioxol-5-yl)-1-hydroxy-11a-methyl-1-(prop-1-yn-1-yl)-1H,2H,3H,3aH …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
LY-377604
Ly377604 has been used in trials studying the treatment of Obesity.
Investigational
Matched Iupac: … 6-[4-(2-{[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino}-2-methylpropyl)phenoxy]pyridine-3-carboxamide …
LV305
LV305 is a lentiviral vector encoding NY-ESO-1 gene. LV305 is an active component of CMB305 along with G305.
Investigational
Matched Description: … LV305 is a lentiviral vector encoding NY-ESO-1 gene. …
mRNA-3927
mRNA-3927 is an investigational mRNA therapy that consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA carboxylase (PCC) encapsulated within a lipid nanoparticle (LNP). Developed by Moderna Inc., it is being investigated for the treatment of propionic acidemia.
Investigational
Recombinant methionyl brain-derived neurotrophic factor
Investigational
Matched Synonyms: … R-Met-hu-bdnf …
(5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID
Experimental
Matched Name: … (5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID …
Matched Iupac: … 2-(5-chloro-2-{[(3-nitrophenyl)methyl]carbamoyl}phenoxy)acetic acid …
Matched Iupac: … 2-(5-chloro-2-{[(3-nitrophenyl)methyl]carbamoyl}phenoxy)acetic acid …
2'-deoxy-5-(hydroxymethyl)uridine 5'-(dihydrogen phosphate)
Experimental
Matched Synonyms: … 5-hydroxymethyluridine-2'-deoxy-5'-monophosphate …
Matched Name: … 2'-deoxy-5-(hydroxymethyl)uridine 5'-(dihydrogen phosphate) …
Matched Iupac: … {[(2R,3S,5R)-3-hydroxy-5-[5-(hydroxymethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl]oxolan-2-yl]methoxy …
Matched Name: … 2'-deoxy-5-(hydroxymethyl)uridine 5'-(dihydrogen phosphate) …
Matched Iupac: … {[(2R,3S,5R)-3-hydroxy-5-[5-(hydroxymethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl]oxolan-2-yl]methoxy …
5-Formyl-2'-deoxy-cytidine-5'-monophosphate
Experimental
Matched Name: … 5-Formyl-2'-deoxy-cytidine-5'-monophosphate …
Matched Iupac: … {[(2R,3S,5R)-5-(4-amino-5-formyl-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic …
Matched Iupac: … {[(2R,3S,5R)-5-(4-amino-5-formyl-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic …
9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE
Experimental
Matched Name: … 9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE …
Matched Iupac: … [3,4-d][1,3]dioxol-2-yl]methyl}phosphonic acid ... {[(2S,3aR,4R,6S,6aS)-4-(hydroxymethyl)-6-{4-oxo-1H,4H,5H-pyrrolo[3,2-d]pyrimidin-7-yl}-tetrahydro-2H-furo …
Matched Iupac: … [3,4-d][1,3]dioxol-2-yl]methyl}phosphonic acid ... {[(2S,3aR,4R,6S,6aS)-4-(hydroxymethyl)-6-{4-oxo-1H,4H,5H-pyrrolo[3,2-d]pyrimidin-7-yl}-tetrahydro-2H-furo …
Displaying drugs 8126 - 8150 of 11562 in total