Displaying drugs 8176 - 8200 of 8817 in total
Recombinant neuroglobin
Investigational
Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine
Experimental
Matched Iupac: … 6-(hydroxymethyl)oxan-4-yl]oxy}propanamido]propanoic acid ... )-2-[(2R)-2-{[(2R,3R,4R,5S,6R)-2-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4 ... -dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3-acetamido-5-hydroxy- …
trans-2-hydroxycinnamic acid
Experimental
Matched Synonyms: … (2E)-3-(2-hydroxyphenyl)-2-propenoic acid ... (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid ... (E)-3-(2-Hydroxyphenyl)-2-propenoic acid …
Matched Iupac: … (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid …
Matched Iupac: … (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid …
Exisulind
Investigational
Matched Synonyms: … 5-Fluoro-2-methyl-1-((Z)-p-(methylsulfonyl)benzylidene)indene-3-acetic acid ... cis-5-Fluoro-2-methyl-1-(p-methylsulfonylbenzylidenyl)indene-3-acetic acid …
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfonylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid …
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfonylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid …
Eldecalcitol
Eldecalcitol (ED-71), a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis. Eldecalcitol, effectively and safely increased lumbar and hip bone mineral density (BMD) in osteoporotic patients who also received vitamin D3 supplementation.
Investigational
Matched Synonyms: … 1α,25-dihydroxy-2β-(3-hydroxypropoxy)cholecalciferol …
Matched Iupac: … ylidene]ethylidene}-2-(3-hydroxypropoxy)-4-methylidenecyclohexane-1,3-diol ... 2R,3R,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden-4- …
Matched Iupac: … ylidene]ethylidene}-2-(3-hydroxypropoxy)-4-methylidenecyclohexane-1,3-diol ... 2R,3R,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden-4- …
Valopicitabine
The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Synonyms: … 2'-C-methylcytidine 3'-O-L-valinyl ester …
Matched Iupac: … 3-yl (2S)-2-amino-3-methylbutanoate ... (2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan- …
Matched Description: … The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
Matched Iupac: … 3-yl (2S)-2-amino-3-methylbutanoate ... (2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan- …
Matched Description: … The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
AFM-13
Investigational
SPG601
SPG601 is being investigated for the treatment of fragile X syndrome.
Investigational
Matched Synonyms: … (R) 3-(5-Dimethylcarbamoyl-pent-1-enyl)-N-(2-hydroxy-1-methylethyl) benzamide …
1-{[1-(2-AMINO-3-PHENYL-PROPIONYL)-PYRROLIDINE-2-CARBONYL]-AMINO}-2-(3-CYANO-PHENYL)-ETHANEBORONIC ACID
Experimental
Matched Name: … 1-{[1-(2-AMINO-3-PHENYL-PROPIONYL)-PYRROLIDINE-2-CARBONYL]-AMINO}-2-(3-CYANO-PHENYL)-ETHANEBORONIC ACID …
Matched Iupac: … [(1R)-1-{[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-2-(3-cyanophenyl)ethyl]boronic …
Matched Iupac: … [(1R)-1-{[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-2-(3-cyanophenyl)ethyl]boronic …
4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE
Experimental
Matched Name: … 4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE …
Matched Iupac: … 5-chloro-2-{[(3R)-3-(2-methylpropyl)-4-[5-(pyridin-4-yl)pyrimidine-2-carbonyl]piperazin-1-yl]sulfonyl …
Matched Iupac: … 5-chloro-2-{[(3R)-3-(2-methylpropyl)-4-[5-(pyridin-4-yl)pyrimidine-2-carbonyl]piperazin-1-yl]sulfonyl …
Hycanthone
Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.
Experimental
Matched Synonyms: … 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one ... 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one …
Matched Iupac: … 1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-9H-thioxanthen-9-one …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … 1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-9H-thioxanthen-9-one …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Tasadenoturev
Investigational
Captodiame
Captodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine. Captodiame has been suggested for use in preventing benzodiazepine withdrawal syndrome.
Experimental
Matched Synonyms: … 2-[(4-butylsulfanylphenyl)-phenyl-methyl]sulfanyl-N,N-dimethylethanamine …
Matched Iupac: … [2-({[4-(butylsulfanyl)phenyl](phenyl)methyl}sulfanyl)ethyl]dimethylamine …
Matched Iupac: … [2-({[4-(butylsulfanyl)phenyl](phenyl)methyl}sulfanyl)ethyl]dimethylamine …
Amprolium
Amprolium is a coccidiostat used in poultry.
Experimental
Vet approved
Matched Synonyms: … 1-((4-amino-2-Propyl-5-pyrimidinyl)methyl)-2-picolinium chloride …
Matched Iupac: … 1-[(4-amino-2-propylpyrimidin-5-yl)methyl]-2-methylpyridin-1-ium chloride …
Matched Iupac: … 1-[(4-amino-2-propylpyrimidin-5-yl)methyl]-2-methylpyridin-1-ium chloride …
Glucoraphanin
Glucoraphanin is under investigation in clinical trial NCT01879878 (Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]).
Investigational
Matched Synonyms: … 4-methylsulfinylbutyl glucosinolate …
Mefuparib
Investigational
Matched Synonyms: … 5-fluoro-2-(4-((methylamino)methyl)phenyl)-7-benzofurancarboxamide …
Matched Iupac: … 5-fluoro-2-{4-[(methylamino)methyl]phenyl}-1-benzofuran-7-carboxamide …
Matched Iupac: … 5-fluoro-2-{4-[(methylamino)methyl]phenyl}-1-benzofuran-7-carboxamide …
Zolbetuximab
Zolbetuximab is under investigation in clinical trial NCT01630083 (Efficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer).
Investigational
Tafolecimab
Tafolecimab is under investigation in clinical trial NCT04031742 (A Study to Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia).
Investigational
3-(1H-tetrazol-5-ylamino)cyclohex-2-en-1-one
Experimental
Matched Name: … 3-(1H-tetrazol-5-ylamino)cyclohex-2-en-1-one …
Matched Iupac: … 3-[(1H-1,2,3,4-tetrazol-5-yl)amino]cyclohex-2-en-1-one …
Matched Iupac: … 3-[(1H-1,2,3,4-tetrazol-5-yl)amino]cyclohex-2-en-1-one …
4-METHYL-PENTANOIC ACID {1-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYLCARBAMOYL]-2-METHYL-PROPYL}-AMIDE
Experimental
Matched Name: … 4-METHYL-PENTANOIC ACID {1-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYLCARBAMOYL]-2-METHYL-PROPYL}-AMIDE …
Matched Iupac: … -1-{[(2S)-5-[(diaminomethyl)amino]-1-oxo-1-(1,3-thiazol-2-yl)pentan-2-yl]carbamoyl}-2-methylpropyl]-4- …
Matched Iupac: … -1-{[(2S)-5-[(diaminomethyl)amino]-1-oxo-1-(1,3-thiazol-2-yl)pentan-2-yl]carbamoyl}-2-methylpropyl]-4- …
Algenpantucel-L
Investigational
Methyl-O3-(Alpha-D-Mannose)-Alpha-D-Mannose
Experimental
Matched Iupac: … (2R,3S,4S,5S,6R)-2-{[(2R,3R,4S,5S,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-methoxyoxan-4-yl]oxy}-6-(hydroxymethyl …
N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide
Experimental
Matched Name: … N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide …
Matched Iupac: … N-(3-cyclopropyl-1H-pyrazol-5-yl)benzamide …
Matched Iupac: … N-(3-cyclopropyl-1H-pyrazol-5-yl)benzamide …
5-Alpha-Androstane-3-Beta,17beta-Diol
Experimental
Matched Name: … 5-Alpha-Androstane-3-Beta,17beta-Diol …
6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE
Experimental
Displaying drugs 8176 - 8200 of 8817 in total