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Displaying drugs 8176 - 8200 of 9648 in total
Racemetyrosine is under investigation in clinical trial NCT03512756 (A Randomized Phase 2/3 Multi-center Study of SM-88 in Patients With Metastatic Pancreatic Cancer).
Investigational
Matched Iupac: … 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid …
Investigational
Matched Iupac: … (2S)-4-carbamoyl-2-(2-phenylacetamido)butanoic acid …
Investigational
Ragifilimab is under investigation in clinical trial NCT04225039 (Anti-gitr/anti-pd1/stereotactic Radiosurgery, in Recurrent Glioblastoma).
Investigational
Brecanavir (VX-385) an orally active aspartic protease inhibitor (PI), under investigation by Vertex and GlaxoSmithKline for the treatment of HIV. In July 2006, Vertex indicated that it expected GSK to initiate phase III trials of the drug in 2007. In December of 2006 GSK announced a decision to discontinue the...
Investigational
Matched Iupac: … ]phenyl}-4-[N-(2-methylpropyl)2H-1,3-benzodioxole-5-sulfonamido]butan-2-yl]carbamate ... (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-1-{4-[(2-methyl-1,3-thiazol-4-yl)methoxy …
Experimental
Matched Iupac: … (2S)-2-(carboxyamino)-4-(methylsulfanyl)butanoic acid …
Experimental
Matched Iupac: … (2S)-2-amino-N-hydroxy-4-methylpentanamide …
Experimental
Matched Iupac: … (2R)-4-methyl-2-(methylamino)pentanoic acid …
Withdrawn from the Canadian market in July 1964 due to interactions with food products containing tyrosine.
Withdrawn
Matched Iupac: … N'-(propan-2-yl)pyridine-4-carbohydrazide …
Bicifadine (DOV-220075) is a nonopioid analgesic. It is an inhibitor of both the norepinephrine and serotonin transporters and an NMDA antagonist with a non-narcotic profile. Bicifadine was shown to have potent analgesic activity in vivo and was chosen for further development for the treatment of pain.
Investigational
Matched Iupac: … 1-(4-methylphenyl)-3-azabicyclo[3.1.0]hexane …
Matched Salts cas: … 66504-75-4
Investigational
Matched Iupac: … 15-[4-(¹²³I)iodophenyl]-3-methylpentadecanoic acid …
Clomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal. It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic, muscle relaxant and anticonvulsant. It...
Investigational
Matched Iupac: … 5-(2-chloroethyl)-4-methyl-1,3-thiazole …
Matched Salts cas: … 6001-74-7
Experimental
Matched Iupac: … 2-{[1,1'-biphenyl]-4-yl}acetic acid …
Diloxanide (as Diloxanide furoate) is an anti-protozoal drug used in the treatment of Entamoeba histolytica and some other protozoal infections. Although it is not currently approved for use in the United States, it was approved by a CDC study in the treatment of 4,371 cases of Entamoeba histolytica from 1977...
Experimental
Matched Iupac: … 2,2-dichloro-N-(4-hydroxyphenyl)-N-methylacetamide …
Benzylfentanyl (R-4129) is a fentanyl analog opioid that was on the list of Schedule I drugs in America in 1985 due to its structural similarity to fentanyl. In 2010 it was removed from the list after it was found to have minimal opioid activity. Benzylfentanyl has a Ki of 213nM...
Illicit
Matched Iupac: … N-(1-benzylpiperidin-4-yl)-N-phenylpropanamide …
Cythioate is a member of the organothiophosphate compounds that is used as an insecticide and anthelmintic. It is mainly used in veterinary as a treatment for fleas.
Vet approved
Matched Iupac: … O,O-dimethyl O-4-sulfamoylphenyl phosphorothioate …
Tetrasul has been used in trials studying the treatment of Erythematous (Type One) Rosacea.
Investigational
Matched Iupac: … 1,2,4-trichloro-5-[(4-chlorophenyl)sulfanyl]benzene …
Cloridarol is an experimental medication in the treatment of heart disease, which acts through vasodilation. It was studied for the treatment of coronary insufficiency in Italy in the 1970s .
Experimental
Matched Iupac: … (1-benzofuran-2-yl)(4-chlorophenyl)methanol …
Experimental
Matched Iupac: … 2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate …
Experimental
Matched Iupac: … [2-(iodomethyl)-1,3-dioxolan-4-yl]methanol …
Experimental
Matched Iupac: … (2S)-2-(2-aminoacetamido)-4-carbamoylbutanoic acid …
Ladarixin is under investigation in clinical trial NCT04628481 (A Study of Oral Ladarixin in New-onset Type 1 Diabetes and a Low Residual Β-Cell Function).
Investigational
Matched Iupac: … 4-[(1R)-1-(methanesulfonylcarbamoyl)ethyl]phenyl trifluoromethanesulfonate …
Experimental
Matched Iupac: … 4-(1H-indol-3-yl)butanoic acid …
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy …
Experimental
Matched Iupac: … (2S,8S)-8-benzyl-2-[(4-bromophenyl)methyl]-2-hydroperoxy-6-(4-hydroxyphenyl)-2H,3H,7H,8H-imidazo[1,2- …
Displaying drugs 8176 - 8200 of 9648 in total