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Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Synonyms: … 6-alpha-ethylchenodeoxycholic acid ... Obeticholic acid ... 6-ethylchenodeoxycholic acid
Matched Name: … Obeticholic acid
Matched Iupac: … 11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Cholic Acids
Prednisolone acetate is a prednisolone molecule bound to an acetate functional group by an ester bond. Prednisolone acetate was granted FDA approval in 1955.
Approved
Vet approved
Matched Synonyms: … Prednisolone acetate
Matched Name: … Prednisolone acetate
Matched Iupac: … 11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate
Matched Description: … Prednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond ... [L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449] …
Matched Products: … Prednisolone Acetate ... Prednisolone Acetate PF ... PREDNISOLONE ACETATE SUSPENSION 25 mg/ml …
Investigational
Matched Synonyms: … Calcium,n,n'-1,2-ethanediylbis(n-((3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methyl)glycine …
Matched Categories: … Enzymes and Coenzymes ... Acetates ... Acids, Acyclic ... Carboxylic Acids
Experimental
Matched Synonyms: … Zinc protoporphyrin-9 ... Zinc-protoporphyrin IX …
Matched Name: … Zinc protoporphyrin …
Matched Iupac: … zinc(2+) 4,20-bis(2-carboxyethyl)-9,14-diethenyl-5,10,15,19-tetramethyl-21,22,23,24-tetraazapentacyclo …
Radiopaque medium used in the diagnosis of gall bladder & bile duct diseases, usually as meglumine salt.
Experimental
Matched Synonyms: … Iodoxamic acid ... Acidum iodoxamicum …
Matched Name: … Iodoxamic acid
Matched Iupac: … 3-carboxy-2,4,6-triiodophenyl)carbamoyl]-3,6,9,12-tetraoxapentadecan-15-amido}-2,4,6-triiodobenzoic acid
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... iodoxamic acid
Investigational
Matched Synonyms: … Alpha-hydroxyoleic acid ... 2-hydroxyoleic acid ... (z)-2-hydroxyoctadec-9-enoic acid
Matched Name: … Idroxioleic acid
Matched Iupac: … (9Z)-2-hydroxyoctadec-9-enoic acid
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of...
Approved
Matched Description: … Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and ... A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … AZATHIOPRIN ACIS 50MG ... AZATHIOPRIN BETA 50MG …
A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones. [PubChem]
Experimental
Matched Synonyms: … UDP-alpha-D-glucuronate ... UDP-Glucuronic Acid ... uridine diphosphate glucuronic acid
Matched Name: … UDP-alpha-D-glucuronic acid
Matched Iupac: … dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
Matched Description: … It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. ... A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis ... In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Approved
Matched Synonyms: … Desoxycortone acetate ... Deoxycorticosterone acetate ... 11-deoxycorticosterone acetate
Matched Name: … Desoxycorticosterone acetate
Matched Iupac: … -oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Fludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to aldosterone, the body's primary endogenous mineralocorticoid, and is structurally analogous to cortisol, differing only by a fluorine atom at the 9-position of the steroid structure...
Approved
Investigational
Matched International brands: … Florinef Acetaat
Matched Description: … A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and
Matched Salts name: … Fludrocortisone acetate
Matched Categories: … Sex Hormones and Insulins ... fludrocortisone and antiinfectives ... fludrocortisone and antiinfectives ... Hormones, Hormone Substitutes, and Hormone Antagonists ... fludrocortisone and antiinfectives …
Matched Products: … Florinef Acetate ... Fludrocortisone Acetate ... Florinef Acetate 0.1mg …
Experimental
Matched Synonyms: … β-D-galacturonic acid ... β-D-Galactopyranuronic acid
Matched Name: … beta-D-Galactopyranuronic acid
Matched Iupac: … (2S,3R,4S,5R,6R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Synonyms: … fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid ... -fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
Matched Iupac: … fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
Matched Description: … hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid ... clinical studies to result in a 45.8% to 54.6% decreases in LDL cholesterol levels, which is about three-fold ... belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and
Matched Mixtures name: … Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe …
Matched Salts name: … Rosuvastatin calcium ... Rosuvastatin zinc
Matched Categories: … rosuvastatin and acetylsalicylic acid ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... rosuvastatin and valsartan ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … ROSUVASTATINA BIOCON ... Rosuvastatin Calcium ... Rosuvastatin calcium
Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium® in Hospitalized Patients With Coronavirus Disease COVID-19).
Investigational
Matched Synonyms: … Poly((1-(carboxymethyl)piperazin-1-ium-1,4-diyl bromide)ethylene-co-((piperazin-1,4-diyl 1-oxide)ethylene …
Matched Description: … Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium …
Investigational
Matched Synonyms: … Fumaric acid ... Fumaricum acidum ... (2E)-2-butenedioic acid
Matched Name: … Fumaric acid
Matched Iupac: … (2E)-but-2-enedioic acid
Matched Categories: … Acids, Acyclic ... fumaric acid ... Carboxylic Acids ... Dicarboxylic Acids
Investigational
Matched Synonyms: … Thiasine
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
Magnesium salicylate is a non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain. It is available in several over-the-counter (OTC) formulations. Though the recommended doseage is 1160 mg every six hours, per package directions of the Doan's OTC brand (580 mg magnesium salicylate tetrahydrate, equivalent to 934.4 mg...
Experimental
Matched Synonyms: … Magnesium salicylate ... Magnesium salicylate anhydrous …
Matched Name: … Magnesium salicylate …
Matched Iupac: … magnesium(2+) bis(2-hydroxybenzoate) …
Matched Description: … Magnesium salicylate is a non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate ... salicylate tetrahydrate, equivalent to 934.4 mg anhydrous magnesium salicylate), effective pain relief ... recommended doseage is 1160 mg every six hours, per package directions of the Doan's OTC brand (580 mg magnesium
Matched Mixtures name: … First Aid Direct Backache and Muscle Relief …
Matched Salts name: … Magnesium salicylate tetrahydrate …
Matched Categories: … Salicylic Acid and Derivatives ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids ... Magnesium Salts …
Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Synonyms: … Clavulanic acid ... Acide clavulanique ... Acidum clavulanicum …
Matched Name: … Clavulanic acid
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Description: … Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin ... [T665] Clavulanic acid is derived from the organism Streptomyces clavuligerus. ... [A182228]When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav …
Matched Mixtures name: … ACIX® ... AMOXICILLINA E ACIDO CLAVULANICO KABI ... AMOXICILLINA E ACIDO CLAVULANICO KABI …
Matched Categories: … beta-Lactams ... beta-Lactamase Inhibitors …
Approved
Matched Synonyms: … Ferrous cysteine glycinate chelate (1:2:1) …
Matched Name: … Ferrous cysteine glycinate …
Matched Iupac: … lambda2-iron(2+) (2R)-2-amino-3-sulfanylpropanoic acid 2-aminoacetic acid (2R)-2-amino-3-sulfanidylpropanoate …
Approved
Experimental
Matched Synonyms: … Magnesium aluminometasilicate …
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Synonyms: … Pyridine-4-carboxylic acid hydrazide ... Isonicotinic acid hydrazide …
Matched Iupac: … pyridine-4-carbohydrazide …
Matched Categories: … isoniazid, sulfamethoxazole, trimethoprim and pyridoxine ... Acids, Heterocyclic ... Isonicotinic Acids ... Fatty Acid Synthesis Inhibitors ... ethambutol and isoniazid …
Approved
Vet approved
Withdrawn
Matched Synonyms: … carbamic acid 3-(p-chlorophenoxy)-2-hydroxypropyl ester ... Chlorphenesin carbamate ... 1,2-propanediol-3-(p-chlorophenoxy)-1-carbamate
Matched Name: … Chlorphenesin carbamate
Matched Iupac: … 3-(4-chlorophenoxy)-2-hydroxypropyl carbamate
Experimental
Matched Synonyms: … L-alpha-Amino-delta-hydroxyvaleric acid ... 5-Hydroxy-2-aminovaleric acid
Matched Iupac: … (2S)-2-amino-5-hydroxypentanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins …
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Synonyms: … glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate ester ... 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid ... 2-[(2',6'-dichlorophenyl)amino]phenylacetoxyacetic acid
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Acids, Carbocyclic ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit...
Approved
Nutraceutical
Withdrawn
Matched Synonyms: … (S)-alpha-Amino-beta-(3-indolyl)-propionic acid ... (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid ... (S)-α-amino-1H-indole-3-propanoic acid
Matched Iupac: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
Matched Description: … An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults ... It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). ... It can be a precursor to niacin, albeit inefficiently, in mammals. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Aminosyn II with Electrolytes in Dextrose with Calcium
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic ... Amino Acids, Essential …
Investigational
Matched Synonyms: … .beta.-d-galactopyranoside, (3.beta.,5.alpha.,22.alpha.,25r)-26-(.beta. ... -d-glucopyranosyloxy)-22-hydroxyfurostan-3-yl o-.beta.-d-glucopyranosyl-(1->2)-o-(.beta. ... -d-xylopyranosyl-(1->3))-o-.beta.-d-glucopyranosyl-(1->4)- …
Displaying drugs 801 - 825 of 3700 in total