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Displaying drugs 801 - 825 of 1148 in total
Vespula pensylvanica venom protein is an extract of Vespula pensylvanica venom. Vespula pensylvanica venom protein is used in allergenic testing.
Approved
Matched Synonyms: … western yellow jacket venom protein
Matched Name: … Vespula pensylvanica venom protein
Matched Description: … Vespula pensylvanica venom protein is used in allergenic testing. ... Vespula pensylvanica venom protein is an extract of Vespula pensylvanica venom. …
Matched Categories: … Bee and Wasp Venom …
STX-100 is under investigation in clinical trial NCT01371305 (STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).
Investigational
Matched Synonyms: … Humanized monoclonal antibody against human integrin alphaVbeta6 …
Investigational
Matched Synonyms: … TCN-202 (human anti-cytomegalovirus monoclonal antibody) …
Investigational
Matched Synonyms: … Deoxyribonuclease (synthetic human), amide with 1,2-ethanediamine …
CER-001 is a negatively charged lipoprotein particle comprising human recombinant apolipoprotein A-I and two phospholipids: sphingomyelin and dipalmitoylphosphatidylglycerol. It is under investigation for the treatment of lecithin-cholesterol acyltransferase (LCAT) deficiencies.
Investigational
Matched Synonyms: … Recombinant human apolipoprotein A-I/phospholipid complexes …
Matched Description: … and two phospholipids: sphingomyelin and dipalmitoylphosphatidylglycerol. ... CER-001 is a negatively charged lipoprotein particle comprising human recombinant apolipoprotein A-I …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins
HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment of hepatocellular carcinoma.
Investigational
Matched Synonyms: … recombinant human IgG4 monoclonal antibody against FGF19 …
Matched Description: … HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment …
Bevifimod is under investigation in clinical trial NCT01749787 (Safety Study of PRTX-100 With Methotrexate or Leflunomide to Treat Active Rheumatoid Arthritis).
Investigational
Matched Synonyms: … STAPHYLOCOCCAL PROTEIN A …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Bacterial Proteins
Cry5B is a pore-forming crystal protein produced by and derived from the soil bacterium Bacillus thuringiensis. With demonstrated anthelmintic properties, it has been investigated in the treatment of parasitic intestinal infections.[A259372, A259377]
Investigational
Matched Synonyms: … Bacillus thuringiensis Cry5B Protein
Matched Description: … Cry5B is a pore-forming crystal protein produced by and derived from the soil bacterium _Bacillus thuringiensis …
Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration.[L48852,A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant G-CSF like efbemalenograstim...
Approved
Matched Synonyms: … Rh g-csf fc fusion protein f-627 ... Recombinant dimeric g-csf fusion protein f627 …
Matched Description: … thus reducing the severity and duration of neutropenia. ... GC-627-05 in the US and Europe respectively. ... A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1 (236-alanine,237-alanine,de-c-terminal-lysine), anti-(human receptor tigit)(human-mus ... musculus monoclonal ab154 .gamma.1-chain), disulfide with human-mus musculus monoclonal ab154 .kappa …
Matched Description: … Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination …
Avizakimab is under investigation in clinical trial NCT03371251 (Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care).
Investigational
Matched Synonyms: … Immunoglobulin g1 (251-tyrosine,253-threonine,255-glutamic acid), anti-(human interleukin 21) (human-mus ... musculus monoclonal bos161721 .gamma.1-chain), disulfide with human-mus musculus monoclonal bos161721 …
Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Approved
Investigational
Matched Description: … Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol …
Matched Mixtures name: … Prenatal Vitamin and Mineral Supplement ... Prenatal Vitamin and Mineral Supplement Tab ... Multiple Vitamins and Minerals …
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Skin and Mucous Membrane Agents …
Matched Products: … Ascazin Capsules (Zinc 50.96mg) …
Investigational
Matched Synonyms: … Immunoglobulin g1, (humanized monoclonal 3e10 .gamma.1-chain fab fragment) fusion protein with 67-952 ... -glucosidase (human recombinant), disulfide with humanized monoclonal 3e10 .kappa.-chain ... cell-penetrating humanized fab fragment targeting the equilibrative nucleoside transporter 2 (ent2), fused with a human
Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as DB13999 . It is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It...
Approved
Investigational
Matched Synonyms: … Antihemophilic factor (recombinant, FC fusion protein) ... Antihemophilic Factor (Recombinant BDD), FC Fusion Protein ... Coagulation factor VIII recombinant immunoglubulin g1 fusion protein
Matched Description: … is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. ... other hemorrhages that cause chronic pain and disability to patients [A31551, A31552]. ... Patients with this disorder are more susceptible to recurrent bleeding episodes and excessive bleeding …
Matched Categories: … Human Antihemophilic Factors …
Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome. Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizimâ„¢. The recommended dose is 2 mg per kg given intravenously over...
Approved
Investigational
Matched Synonyms: … Recombinant human N-acetylgalactosamine-6-sulfatase ... Recombinant human N-acetylgalactosamine-6-sulfatase (rhGALNS) …
Matched Description: … Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim …
Matched Categories: … Recombinant Proteins ... Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Chondroitinases and Chondroitin Lyases …
Stem cells are self-renewing and proliferate without differentiation, with the two major groups being embryonic stem cells (ESCs) and adult stem cells (ASC). Differentiation occurs under different conditions into different cell types. ESCs are from the inner cell mass of blastocysts while ASCs are deposited into adult tissues with restricted...
Investigational
Matched Name: … Human Menstrual Blood-derived Stem Cells …
Matched Description: … embryonic stem cells (ESCs) and adult stem cells (ASC). ... Stem cells are self-renewing and proliferate without differentiation, with the two major groups being ... These cells possess a high rate of proliferation and multi-lineage differentiation potency. …
Investigational
Matched Name: … Human Embryonic Stem Cell-derived Astrocytes …
Umbilical-cord derived MSCs are currently being tested for numerous clinical applications due to their immunosuppressive and anti-inflammatory properties. In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally regarded as less immunogenic. The condition medium (CM) derived from these MSCs has also been implicated...
Investigational
Matched Synonyms: … Allogeneic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media ... Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …
Matched Name: … Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …
Matched Description: … derived MSCs are currently being tested for numerous clinical applications due to their immunosuppressive and ... In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally …
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Synonyms: … Human somatomedin C ... INSULIN-LIKE GROWTH FACTOR I (HUMAN) ... RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-I …
Matched Description: … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a ... The rhIGF-1 protein is synthesized in bacteria (E. coli) that have been modified by the addition of the ... gene for human IGF-1. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Human Insulin-like Growth Factor Analogs ... Recombinant Human Insulin-like Growth Factor-1 ... Proteins
Approved
Matched Synonyms: … Recombinant haemagglutinin protein-strain A (H3N2) …
Pegzilarginase is under investigation in clinical trial NCT02488044 (A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency).
Investigational
Matched Synonyms: … Optimised human arginase I ... Co-ArgI-PEG modified human arginase I …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Fecal microbiota, given either as a rectal transplant or in an oral formulation of live spores, is an FDA-approved option to prevent the recurrence of Clostridioides difficile infection (CDI) in patients given an antibacterial treatment for recurrent CDI.[A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases...
Approved
Investigational
Matched Synonyms: … Donor human stool ... Donor human stool spores (ethanol treated) …
Matched Description: … Human fecal matter is then tested for a panel of transmissible pathogens and processed with methods aimed ... Recurrent CDI has a high risk of mortality and a high failure rate. ... [A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases requiring …
Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism.
Approved
Investigational
Matched Synonyms: … Thrombomodulin (human 498-amino acid fragment) …
Matched Description: … It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential ... Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). ... treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Membrane Proteins
Approved
Matched Synonyms: … Human adenovirus B serotype 7 strain 55142 antigen …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Live Human Adenovirus Type 7 Vaccine …
Investigational
Matched Synonyms: … Recombinant human highly phosphorylated acid alpha-glucosidase …
Matched Name: … Recombinant human highly phosphorylated acid alpha-glucosidase …
Displaying drugs 801 - 825 of 1148 in total