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Displaying drugs 8226 - 8250 of 12590 in total

Velafermin

Velafermin was a novel investigational protein therapeutic, also known as fibroblast growth factor-20 (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated activity in multiple animal models. Velafermin was investigated as a potential therapy for the prevention and treatment of oral mucositis by fostering the...
Investigational

Phenylferricrocin-iron

Experimental
Matched Iupac: … N-{3-[(2S,5S,11R,17S)-11-benzyl-5,17-bis[3-(N-hydroxyacetamido)propyl]-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16 ... -hexaazacyclooctadecan-2-yl]propyl}-N-hydroxyacetamide iron …

INHIBITOR Q8467 OF DUPONT MERCK

Experimental
Matched Iupac: … 3-{[(4R,5S,6S,7R)-4,7-dibenzyl-3-(cyclopropylmethyl)-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl]methyl}-N- ... (1,3-thiazol-2-yl)benzamide …

Cloprostenol

Vet approved
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl ... ]hept-5-enoic acid …
Matched Salts cas: … 55028-72-3 …

Icaridin

Icaridin, also known as Picaridin or hydroxy-ethyl isobutyl piperidine carboxylate, is a cyclic amine and a member of the piperidine chemical family. Piperidines are structural components of piperine, which is a plant extract from the genus _Piper _, or pepper. Icaridin has been commonly used as a topically-applied insect repellent...
Experimental
Matched Iupac: … butan-2-yl 2-(2-hydroxyethyl)piperidine-1-carboxylate …

gp209-2M antigen

The gp209-2M antigen is derived from gp209, and has potential immunomodulatory and antineoplastic activities.
Investigational

Bis(5-Amidino-2-Benzimidazolyl)Methane Ketone

Experimental
Matched Name: … Bis(5-Amidino-2-Benzimidazolyl)Methane Ketone …
Matched Iupac: … {azaniumyl[2-(6-carbamimidoyl-1H-1,3-benzodiazole-2-carbonyl)-1H-1,3-benzodiazol-5-yl]methylidene}azanium …

N-(2-Flouro-Benzyl)-4-Sulfamoyl-Benzamide

Experimental
Matched Name: … N-(2-Flouro-Benzyl)-4-Sulfamoyl-Benzamide …
Matched Iupac: … N-[(2-fluorophenyl)methyl]-4-sulfamoylbenzamide …

(S)-alpha-methyl-4-carboxyphenylglycine

Experimental
Matched Synonyms: … (S)-(+)-α-amino-4-carboxy-2-methylbenzeneacetic ... (S)-MCPG ... (S)-a-methyl-4-carboxyphenylglycine …
Matched Name: … (S)-alpha-methyl-4-carboxyphenylglycine …

Methylenedioxyethamphetamine

Experimental
Illicit
Matched Iupac: … [1-(2H-1,3-benzodioxol-5-yl)propan-2-yl](ethyl)amine …

AdimrSC-2f

The AdimrSC-2f (SARS-CoV-2) vaccine is developed through Adimmune Corporation, the only influenza vaccine manufacturer with both EU GMP and US FDA certification in Asia . A phase I study (NCT04522089) will investigate the safety and immunogenicity of the vaccine[L30553, L30548].
Investigational
Matched Description: … The AdimrSC-2f (SARS-CoV-2) vaccine is developed through Adimmune Corporation, the only influenza vaccine …

PKI-179

PKI-179 has been used in trials studying the treatment of Advanced Malignant Solid Tumors.
Investigational
Matched Iupac: … 3-{4-[4-(morpholin-4-yl)-6-[(1R,5S)-3-oxa-8-azabicyclo[3.2.1]octan-8-yl]-1,3,5-triazin-2-yl]phenyl}-1 …

2'-Deoxyuridine 5'-alpha,beta-imido-triphosphate

Experimental
Matched Name: … 2'-Deoxyuridine 5'-alpha,beta-imido-triphosphate …
Matched Iupac: … ({[({[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy …

9-Butyl-8-(2,5-Dimethoxy-Benzyl)-9h-Purin-6-Ylamine

Experimental

HGS-TR2J

HGS-TR2J is a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced solid malignancies. It is developed by Human Genome Sciences, Inc and is under Phase I of clinical trial.
Investigational
Matched Description: … HGS-TR2J is a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced …

INM004

INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being investigated to treat Shiga-toxin producing bacterial infection relating to the prevention of hemolytic uremic syndrome.
Investigational
Matched Synonyms: … Anti-Shiga toxin hyperimmune equine immunoglobulin F(ab')2 fragment ... Neutralizing equine anti-Stx hyperimmune immunoglobulin F(ab')2 fragment …
Matched Description: … INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being …

S-(2-Acetamidoethyl) hexadecanethioate

Experimental
Matched Synonyms: … S-palmitoyl-N-acetylcysteamine …
Matched Name: … S-(2-Acetamidoethyl) hexadecanethioate …
Matched Iupac: … N-[2-(hexadecanoylsulfanyl)ethyl]acetamide …

17-METHYL-17-ALPHA-DIHYDROEQUILENIN

Experimental

Hyodeoxycholic Acid

Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
Investigational
Matched Iupac: … (4R)-4-[(1R,3aS,3bS,5S,5aR,7R,9aR,9bS,11aR)-5,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …
Matched Salts cas: … 10421-49-5 …

Disomotide

Disomotide is a synthetic peptide cancer vaccine.
Investigational

Nitroxoline

Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. It is a hydroxyquinoline derivative unrelated to other classes of drugs. Nitroxoline is active against bacterial gyrases.
Experimental
Matched Synonyms: … 5-NOK ... 5-Nitrox ... 5-Nitro-8-quinolinol …
Matched Iupac: … 5-nitroquinolin-8-ol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

AP5346

AP5346 is designed to target a diaminocyclohexane platinum (Pt) moiety to tumors through pH-sensitive linkage to a 25 kDa hydroxypropylmethacrylamide polymer. It is being pursued by Access Pharmaceuticals, Inc.
Investigational

AP5280

AP5280 is a novel N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-bound platinum (Pt) therapeutic designed to increase the therapeutic index relative to conventional, small-molecule platinum agents.
Investigational
Matched Description: … AP5280 is a novel N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-bound platinum (Pt) therapeutic …

GC5107

GC5107 is an investigational intravenous immunoglobulin. It is marketed as IVIG-SN.
Investigational

Toralizumab

Toralizumab is under investigation in clinical trial NCT03605927 (CD40-L Blockade for Prevention of Acute Graft-versus-host Disease).
Investigational
Displaying drugs 8226 - 8250 of 12590 in total