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Displaying drugs 8251 - 8275 of 11622 in total

Bindarit

Bindarit has been used in trials studying the prevention and treatment of Coronary Restenosis and Diabetic Nephropathy.
Investigational
Matched Iupac: … 2-[(1-benzyl-1H-indazol-3-yl)methoxy]-2-methylpropanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Pinazepam

Experimental
Matched Iupac: … 7-chloro-5-phenyl-1-(prop-2-yn-1-yl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Pinatuzumab vedotin

Pinatuzumab vedotin is under investigation in clinical trial NCT01691898 (A Study of Pinatuzumab Vedotin (DCDT2980S) Combined With Rituximab or Polatuzumab Vedotin (DCDS4501A) Combined With Rituximab or Obinutuzumab in Participants With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)).
Investigational

Adenylosuccinic acid

Experimental
Matched Iupac: … (2S)-2-({9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-9H-purin-6-yl}amino)butanedioic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Apadenoson

Apadenoson is a selective A2a adenosine receptor agonist designed for use as a pharmacologic stress agent in cardiac perfusion imaging studies. It is developed by Bristol-Myers Squibb and is in phase II of clinical trials.
Investigational
Matched Iupac: … methyl (1r,4r)-4-(3-{6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]-9H-purin-2 ... -yl}prop-2-yn-1-yl)cyclohexane-1-carboxylate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Cefatrizine

Experimental
Matched Iupac: … -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-8-oxo-3-[(1H-1,2,3-triazol-4-ylsulfanyl)methyl] …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Cefsulodin

Experimental
Matched Iupac: … 4-carbamoyl-1-{[(6R,7R)-2-carboxy-8-oxo-7-[(2R)-2-phenyl-2-sulfoacetamido]-5-thia-1-azabicyclo[4.2.0] ... oct-2-en-3-yl]methyl}pyridin-1-ium …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Cefazedone

Experimental
Matched Iupac: … yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[2-(3,5-dichloro-4-oxo-1,4-dihydropyridin-1-yl)acetamido]-3-{[(5-methyl-1,3,4-thiadiazol-2- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

RI 624

RI 624 is a novel humanized monoclonal antibody that blocks nerve growth factor (NGF), a key mediator of acute and chronic pain. RI 624 is being developed by Rinat and is currently in Phase I clinical trials.
Investigational

CRA_10655

Experimental
Matched Iupac: … 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2-yl}-6-(cyclopentyloxy)benzen-1-olate …

PG-701

Hydroxytriptolide has been investigated for the treatment of Rheumatoid Arthritis.
Investigational
Matched Iupac: … (1S,2S,4S,5S,7R,8R,9S,11S,13R)-8,13-dihydroxy-1-methyl-7-(propan-2-yl)-3,6,10,16-tetraoxaheptacyclo[11.7.0.0 …

CRA_10972

Experimental
Matched Iupac: … 6-chloro-2-[2-hydroxy-3-(2-methylpropoxy)phenyl]-1H-1,3-benzodiazole-5-carboximidamide …

CRA_11092

Experimental
Matched Iupac: … 6-fluoro-2-(2-hydroxy-3-{[(1S,2S)-2-methylcyclohexyl]oxy}phenyl)-1H-1,3-benzodiazole-5-carboximidamide …

Pegvorhyaluronidase alfa

Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Investigational

Velafermin

Velafermin was a novel investigational protein therapeutic, also known as fibroblast growth factor-20 (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated activity in multiple animal models. Velafermin was investigated as a potential therapy for the prevention and treatment of oral mucositis by fostering the...
Investigational

Gibberellin A4

Experimental

Alogabat

Investigational

(4R,5R)-1,2-dithiane-4,5-diol

Experimental

Willardiine

Willardiine is a compound isolated from seeds of Acacia willariana.
Experimental

Telapristone acetate

Telapristone acetate, an orally-available, selective progesterone receptor modulator, is in development to alleviate symptoms associated with both uterine fibroids and endometriosis.
Investigational
Matched Iupac: … (1R,3aS,3bS,10R,11aS)-10-[4-(dimethylamino)phenyl]-1-(2-methoxyacetyl)-11a-methyl-7-oxo-1H,2H,3H,3aH, …

ABT-341

ABT-341 is a potent and selective DPP-4 inhibitor with a structure very similar to sitagliptin (in 2D; the 3D structure is significantly different).
Experimental

Florfenicol

Florfenicol is a fluorinated synthetic analog of thiamphenicol.
Experimental
Vet approved
Matched Iupac: … 2,2-dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide …

Antineoplaston A10

Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others.
Investigational
Matched Iupac: … N-[(3S)-2,6-dioxopiperidin-3-yl]-2-phenylacetamide …

QXL138AM

QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
Investigational

LY231514 tetra glu

Experimental
Matched Iupac: … 2-[(4S)-4-[(4S)-4-[(4S)-4-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido …
Displaying drugs 8251 - 8275 of 11622 in total