Cefsulodin

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name

Cefsulodin

DrugBank Accession Number

DB13499

Background

Not Available

Type

Small Molecule

Groups

Experimental

Structure

Similar Structures

Weight: Average: 532.54
Monoisotopic: 532.072255968
Chemical Formula: C₂₂H₂₀N₄O₈S₂

Synonyms

Cefsulodin
cefsulodino

External IDs

J01DD03

Pharmacology

Indication: Not Available
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Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half-life: Not Available
Clearance: Not Available
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Toxicity: Not Available
Pathways: Not Available
Pharmacogenomic Effects/ADRs: Not Available

Interactions

Drug Interactions

This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

Drug	Interaction
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Abacavir	Cefsulodin may decrease the excretion rate of Abacavir which could result in a higher serum level.
Abciximab	The therapeutic efficacy of Abciximab can be decreased when used in combination with Cefsulodin.
Aceclofenac	The risk or severity of nephrotoxicity can be increased when Aceclofenac is combined with Cefsulodin.
Acemetacin	The risk or severity of nephrotoxicity can be increased when Cefsulodin is combined with Acemetacin.
Acenocoumarol	The risk or severity of bleeding can be increased when Cefsulodin is combined with Acenocoumarol.
Acetaminophen	Cefsulodin may decrease the excretion rate of Acetaminophen which could result in a higher serum level.
Acetylsalicylic acid	The risk or severity of nephrotoxicity can be increased when Acetylsalicylic acid is combined with Cefsulodin.
Aclidinium	Cefsulodin may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine	Cefsulodin may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Acyclovir	The risk or severity of nephrotoxicity can be increased when Acyclovir is combined with Cefsulodin.

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Food Interactions

Not Available

Chemical Identifiers

UNII: OV42LHE42B
CAS number: 62587-73-9
InChI Key: SYLKGLMBLAAGSC-QLVMHMETSA-N
InChI: InChI=1S/C22H20N4O8S2/c23-18(27)13-6-8-25(9-7-13)10-14-11-35-21-15(20(29)26(21)16(14)22(30)31)24-19(28)17(36(32,33)34)12-4-2-1-3-5-12/h1-9,15,17,21H,10-11H2,(H4-,23,24,27,28,30,31,32,33,34)/t15-,17-,21-/m1/s1
IUPAC Name: 4-carbamoyl-1-{[(6R,7R)-2-carboxy-8-oxo-7-[(2R)-2-phenyl-2-sulfoacetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium
SMILES: NC(=O)C1=CC=[N+](CC2=C(N3[C@H](SC2)[C@H](NC(=O)[C@@H](C2=CC=CC=C2)S(O)(=O)=O)C3=O)C([O-])=O)C=C1

References

General References

Not Available

External Links

KEGG Compound: C11253
ChemSpider: 570942
RxNav: 2190
ChEBI: 3507
ChEMBL: CHEMBL3351077
Wikipedia: Cefsulodin

Clinical Trials

Clinical Trials

Phase	Status	Purpose	Conditions	Count

Pharmacoeconomics

Manufacturers: Not Available
Packagers: Not Available
Dosage Forms: Not Available
Prices: Not Available
Patents: Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
Water Solubility	0.0186 mg/mL	ALOGPS
logP	-1.8	ALOGPS
logP	-5.8	Chemaxon
logS	-4.5	ALOGPS
pKa (Strongest Acidic)	-1.4	Chemaxon
pKa (Strongest Basic)	-0.7	Chemaxon
Physiological Charge	-1	Chemaxon
Hydrogen Acceptor Count	8	Chemaxon
Hydrogen Donor Count	3	Chemaxon
Polar Surface Area	190.88 Å²	Chemaxon
Rotatable Bond Count	8	Chemaxon
Refractivity	139.44 m³·mol^-1	Chemaxon
Polarizability	49.58 Å³	Chemaxon
Number of Rings	4	Chemaxon
Bioavailability	1	Chemaxon
Rule of Five	No	Chemaxon
Ghose Filter	No	Chemaxon
Veber's Rule	No	Chemaxon
MDDR-like Rule	Yes	Chemaxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST)

Not Available

Spectra

Spectrum	Spectrum Type	Splash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)	Predicted LC-MS/MS	Not Available

Drug created at June 23, 2017 20:43 / Updated at February 21, 2021 18:54

Cefsulodin

Identification

Structure for Cefsulodin (DB13499)

Pharmacology

Interactions

Categories

Chemical Identifiers

References

Clinical Trials

Pharmacoeconomics

Properties

Spectra