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Displaying drugs 8451 - 8475 of 12463 in total

Serdemetan

Serdemetan has been used in trials studying the treatment of Neoplasms.
Investigational
Matched Iupac: … N1-[2-(1H-indol-3-yl)ethyl]-N4-(pyridin-4-yl)benzene-1,4-diamine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

AVR-RD-05

AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced ex vivo with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme. It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).
Investigational
Matched Synonyms: … genetically modified autologous cell therapy intended for the stable provision of functional human iduronate-2- …
Matched Description: … modified autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human iduronate-2- …

Chlormadinone

Experimental
Matched Iupac: … 14R,15S)-14-acetyl-8-chloro-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-6,8-dien-5- …
Matched Mixtures name: … BELARA 0.03 mg/2 mg film-coated tablets …

O1-Methyl-4-Deoxy-4-Thio-Alpha-D-Glucose

Experimental
Matched Iupac: … (2S,3R,4R,5S,6R)-6-(hydroxymethyl)-2-methoxy-5-sulfanyloxane-3,4-diol …

Ripertamab

Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated Cd20(cluster of Differentiation Antigen 20)-positive DLBCL Patients).
Investigational
Matched Description: … is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop …

N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE

Experimental
Matched Name: … N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE …
Matched Iupac: … N4-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-N1,N1-dimethylbenzene-1,4-diamine …

2X-121

2X-121 is under investigation in clinical trial NCT03562832 (Investigation of Anti-tumour Effect and Tolerability of the PARP Inhibitor 2X-121 in Patients With Metastatic Breast Cancer Selected by the 2X-121 DRP).
Investigational
Matched Iupac: … 11-[(2,3-dihydro-1H-isoindol-2-yl)methyl]-2,3,10,12-tetraazatricyclo[7.3.1.0^{5,13}]trideca-1,5,7,9(13 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Danirixin

Danirixin has been used in trials studying the treatment and basic science of Virus Diseases, Nutritional Status, Pulmonary Disease, Chronic Obstructive, and Infections, Respiratory Syncytial Virus.
Investigational
Matched Iupac: … 1-{4-chloro-2-hydroxy-3-[(3S)-piperidine-3-sulfonyl]phenyl}-3-(3-fluoro-2-methylphenyl)urea …

S,S-Propylthiocysteine

Experimental
Matched Name: … S,S-Propylthiocysteine …
Matched Iupac: … (2R)-2-amino-3-(propyldisulfanyl)propanal …

4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol

Experimental
Matched Name: … 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol …
Matched Iupac: … 4-{2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl}phenol …

2-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINE

Experimental
Matched Name: … 2-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINE …
Matched Iupac: … 5-(propan-2-yl)-2-[(3S)-1,2,3,4-tetrahydroisoquinolin-3-yl]-1,3-thiazole-4-carboxylic acid …

MRT5201

Investigational

5'-deoxy-5'-piperidin-1-ylthymidine

Experimental
Matched Name: … 5'-deoxy-5'-piperidin-1-ylthymidine …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-[(piperidin-1-yl)methyl]oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine- …

N-[4-(AMINOSULFONYL)BENZYL]-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE

Experimental
Matched Name: … N-[4-(AMINOSULFONYL)BENZYL]-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE …
Matched Iupac: … 5-(5-chloro-2,4-dihydroxyphenyl)-N-[(4-sulfamoylphenyl)methyl]-1H-pyrazole-4-carboxamide …

4-{[5-(CYCLOHEXYLMETHOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE

Experimental
Matched Name: … 4-{[5-(CYCLOHEXYLMETHOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE …
Matched Iupac: … 4-{[5-(cyclohexylmethoxy)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzene-1-sulfonamide …

Fluocortin

Fluocortin has been studied as a corticosteroid for treatment of dermatitis and eczema Spain .
Experimental
Matched Iupac: … 2-[(1S,2R,8S,10S,11S,13R,14S,15S,17S)-8-fluoro-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^{ ... 2,7}.0^{11,15}]heptadeca-3,6-dien-14-yl]-2-oxoacetic acid …

Vorolanib

Vorolanib is under investigation in clinical trial NCT03904719 (CM082 and JS001 in Patients With Advanced Small-cell Lung Cancer (SCLC)).
Investigational
Matched Iupac: … N-[(3S)-1-(dimethylcarbamoyl)pyrrolidin-3-yl]-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene] ... methyl}-2,4-dimethyl-1H-pyrrole-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID

Experimental
Matched Name: … N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID …
Matched Iupac: … 5-[methyl({4-[(1E)-2-(4-nitrophenyl)ethenyl]phenyl})amino]pentanoic acid …

Tropifexor

Tropifexor is under investigation in clinical trial NCT02516605 (A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC Patients).
Investigational
Matched Iupac: … 2-[(1R,3R,5S)-3-({5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl}methoxy)-8-azabicyclo[ …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

5-fluorotryptophan

5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy.
Experimental
Matched Synonyms: … 5-fluoro-L-tryptophan ... L-5-fluorotryptophan …
Matched Name: … 5-fluorotryptophan …
Matched Iupac: … (2S)-2-amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid …
Matched Description: … 5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy. …

beta-D-arabinofuranose 5-phosphate

Experimental
Matched Synonyms: … β-D-arabinofuranose 5-phosphate ... 5-O-phosphono-β-D-arabinofuranose …
Matched Name: … beta-D-arabinofuranose 5-phosphate …
Matched Iupac: … {[(2R,3S,4S,5R)-3,4,5-trihydroxyoxolan-2-yl]methoxy}phosphonic acid …

Leptazoline D

Leptazoline D is a polar oxazoline from the Cyanobacterium Leptolyngbya sp. Also see Leptazoline A, Leptazoline B, and Leptazoline C.
Experimental
Matched Iupac: … (2S,3S)-N-(1,3-dihydroxypropan-2-yl)-2,3-dihydroxy-3-[(4S,5S)-2-(2-hydroxyphenyl)-5-methyl-4,5-dihydro …

Propofol Hemisuccinate

Experimental
Matched Iupac: … 4-[2,6-bis(propan-2-yl)phenoxy]-4-oxobutanoic acid …

Lapaquistat

Lapaquistat is under investigation in clinical trial NCT00256178 (Efficacy of Lapaquistat Acetate and Simvastatin in Subjects With Primary Dyslipidemia.).
Investigational
Matched Iupac: … 2-(1-{2-[(3R,5S)-7-chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-1,2,3,5-tetrahydro ... -4,1-benzoxazepin-3-yl]acetyl}piperidin-4-yl)acetic acid …

9,10-Deepithio-9,10-Didehydroacanthifolicin

A specific inhibitor of phosphoserine/threonine protein phosphatase 1 and 2a. It is also a potent tumor promoter. (Thromb Res 1992;67(4):345-54 & Cancer Res 1993;53(2):239-41)
Experimental
Matched Iupac: … '-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl]-5-hydroxy-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2- ... (2R)-3-[(2S,5R,6R,8S)-8-[(2R,3E)-4-[(2R,4'aR,5R,6'S,8'R,8'aS)-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S ... ,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-7'-methylidene-hexahydro-3'H-spiro[oxolane-2,2 ... hydroxy-2-methylpropanoic acid …
Matched Description: … (Thromb Res 1992;67(4):345-54 & Cancer Res 1993;53(2):239-41) …
Displaying drugs 8451 - 8475 of 12463 in total