Displaying drugs 8476 - 8500 of 12024 in total
1-(2,5-dideoxy-5-pyrrolidin-1-yl-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
Experimental
Matched Iupac: … 1-[(2S,4R,5S)-4-hydroxy-5-[(pyrrolidin-1-yl)methyl]oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine …
Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)
The Recombinant SARS-CoV-2 Vaccine was created by inserting genes of the SARS-CoV-2 spike protein’s receptor-binding domain into a baculovirus expression system[F4738, A226853]. In pre-clinical trial testing on mice, rabbits, and non-human primates, the candidate was able to induce a functional antibody response within 7-14 days of initial injection . It...
Investigational
KD3010
KD3010 is a small molecule peroxisome proliferator-activator receptor delta (PPAR Delta) agonist for the treatment of metabolic disorders, including obesity.
Investigational
Matched Iupac: … 4-methylbenzene-1-sulfonic acid; 4-{[(2R,6S)-2,6-dimethyl-4-[4-(trifluoromethoxy)phenyl]piperazin-1-yl …
BTRX-335140
BTRX-335140 is under investigation in clinical trial NCT04221230 (Study in Major Depressive Disorder With BTRX-335140 vs Placebo).
Investigational
Matched Iupac: … 1-[6-ethyl-8-fluoro-4-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-4-yl)piperidin-4 …
methyl (1R,2S)-2-(hydroxycarbamoyl)-1-{4-[(2-methylquinolin-4-yl)methoxy]benzyl}cyclopropanecarboxylate
Experimental
Matched Name: … methyl (1R,2S)-2-(hydroxycarbamoyl)-1-{4-[(2-methylquinolin-4-yl)methoxy]benzyl}cyclopropanecarboxylate …
Matched Iupac: … methyl (1R,2S)-2-(hydroxycarbamoyl)-1-({4-[(2-methylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane- …
Matched Iupac: … methyl (1R,2S)-2-(hydroxycarbamoyl)-1-({4-[(2-methylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane- …
Pralnacasan
Pralnacasan is an orally bioavailable pro-drug of a potent, non-peptide inhibitor of interleukin-1beta converting enzyme (ICE).
Investigational
Matched Iupac: … N-[(4S,7S)-4-{[(2R,3S)-2-ethoxy-5-oxooxolan-3-yl]carbamoyl}-6,10-dioxo-octahydro-1H-pyridazino[1,2-a] …
Rotigaptide
Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease.
Investigational
Matched Iupac: … (2R)-N-(carbamoylmethyl)-2-(2-{[(2R,4S)-1-[(2R)-1-[(2R)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]pyrrolidine ... -2-carbonyl]-4-hydroxypyrrolidin-2-yl]formamido}acetamido)propanamide …
Acarbose Derived Hexasaccharide
Experimental
Matched Iupac: … (2R,3R,4S,5S,6R)-6-({[(2S,3R,4R,5S,6R)-5-{[(2R,3R,4S,5S,6R)-5-{[(1S,4R,5R,6S)-4-{[(2S,3R,4R,5S,6R)-3,4 ... -2-yl]oxy}-5,6-dihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-3,4-dihydroxy-6-methyloxan-2-yl]oxy ... -dihydroxy-6-(hydroxymethyl)-5-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan …
Poloxamer 407
Poloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant. It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks, both hydrophilic in nature. Poloxamer 407 is used as an emulsifying agent and solubilizing agent in cosmetic and personal products...
Investigational
p-Heptylphenol
Experimental
Matched Synonyms: … 4-Heptylphenol ... 4-n-Heptylphenol …
Matched Iupac: … 4-heptylphenol …
Matched Iupac: … 4-heptylphenol …
Artemisinin
Artemisinin has been used in trials studying the treatment of Schizophrenia, Malaria, Falciparum, and Plasmodium Falciparum.
Investigational
Matched Iupac: … (1R,4S,5R,8S,9R,12S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0⁴,¹³.0⁸,¹³]hexadecan- …
Cinchonidine
Investigational
Matched Iupac: … (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](quinolin-4-yl)methanol …
Mequitazine
Mequitazine is a histamine H1 antagonist (antihistamine). It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory...
Experimental
Matched Iupac: … 10-({1-azabicyclo[2.2.2]octan-3-yl}methyl)-10H-phenothiazine …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
JS-K
Investigational
Matched Synonyms: … 1-piperazinecarboxylic acid, 4-((2,4-dinitrophenoxy)-nno-azoxy)-, ethyl ester ... 1-piperazinecarboxylic acid, 4-(2-(2,4-dinitrophenoxy)-1-oxidodiazenyl)-, ethyl ester ... O2-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate …
Matched Iupac: … (1Z)-2-(2,4-dinitrophenoxy)-1-[4-(ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1-olate …
Matched Iupac: … (1Z)-2-(2,4-dinitrophenoxy)-1-[4-(ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1-olate …
Ethyl methoxycinnamate
Experimental
Matched Synonyms: … Ethyl (E)-4-methoxycinnamate …
Matched Iupac: … ethyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Matched Iupac: … ethyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
RRx-001
RRx-001 has been used in trials studying the treatment of Lymphomas, Brain Metastases, Cholangiocarcinoma, Colorectal Neoplasms, and Malignant Solid Tumor, among others.
Investigational
BV2
Experimental
Matched Iupac: … 2-amino-3-({[3-(4-{3-[(3-nitro-5-{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl ... )formamido]propyl}piperazin-1-yl)propyl]carbamoyl}oxy)propyl N-[3-(4-{3-[(3-nitro-5-{[3,4,5-trihydroxy …
p-Nitrophenylacetic acid
Experimental
Matched Synonyms: … (4-nitrophenyl)acetic acid ... 4-nitrophenylacetic acid ... 4-nitrobenzeneacetic acid …
Matched Iupac: … 2-(4-nitrophenyl)acetic acid …
Matched Iupac: … 2-(4-nitrophenyl)acetic acid …
Disitamab vedotin
Disitamab vedotin is an antibody-drug conjugate drug targeting human epidermal growth factor receptor 2 (HER2). It is currently being investigated for cancers.
Investigational
1,4-Butanediol
Experimental
Toloxatone
Toloxatone is an antidepressant agent, the first ever use of which was in France, 1984. It acts as a selective and reversible inhibitor of monoamine oxidase-A (MOA) .
Experimental
Matched Iupac: … 5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one …
Displaying drugs 8476 - 8500 of 12024 in total