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Displaying drugs 8476 - 8500 of 11262 in total
Motuporin is a toxin isolated from the marine sponge Thenonella swinhoie grey.
Experimental
Matched Iupac: … (2Z,5R,6S,9S,12S,13S,16R)-2-ethylidene-12-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dien ... -1-yl]-1,6,13-trimethyl-3,7,10,14,19-pentaoxo-9-(propan-2-yl)-1,4,8,11,15-pentaazacyclononadecane-5,16 …
Rocaglamide, also referred to as rocaglamide-A, is the eponymous member of a class of anti-cancer phytochemicals known as rocaglamides. Rocaglamides are secondary metabolites of the plant genus Aglaia, and extracts of the plant have traditionally been used as a form of insect repellant due to its natural insecticidal properties. Reports...
Experimental
Matched Iupac: … (2S,3R,4R,5S,6R)-2,3-dihydroxy-10,12-dimethoxy-6-(4-methoxyphenyl)-N,N-dimethyl-5-phenyl-7-oxatricyclo …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Rilapladib is the third genomics-derived small molecule drug arising from the Human Genome Sciences-GlaxoSmithKline collaboration to enter clinical development. It is a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2 is an enzyme associated with the formation of atherosclerotic plaques.
Investigational
Matched Iupac: … 2-(2-{[(2,3-difluorophenyl)methyl]sulfanyl}-4-oxo-1,4-dihydroquinolin-1-yl)-N-[1-(2-methoxyethyl)piperidin …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Nafithromycin is under investigation in clinical trial NCT02903836 (Phase II Study of Oral Nafithromycin in CABP).
Investigational
Matched Iupac: … -1,3,4-thiadiazol-2-yl]ethoxy]-tetradecahydro-2H-furo[2,3-c]oxacyclotetradecane-3-carboximidamide ... yl]oxy}-15-ethyl-8-methoxy-4,6,8,10,12,15a-hexamethyl-2,5,11,13-tetraoxo-N'-[(1S)-1-[5-(pyridin-2-yl) ... (Z,3R,3aS,4R,6R,8R,9R,10R,12R,15R,15aS)-9-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2- …
Experimental
Matched Name: … 2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol …
Matched Iupac: … 2,6-dimethyl-4-[(1E)-2-phenylethenyl]phenol …
Experimental
Matched Name: … N-(5'-Phosphopyridoxyl)-D-Alanine …
Matched Iupac: … (2R)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]propanoic acid …
Experimental
Matched Name: … 5'-O-(L-Serylsulfamoyl)adenosine …
Matched Iupac: … (2S)-2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl) ... amino]-3-hydroxypropan-1-one …
Experimental
Matched Name: … (C8-S)-Hydantocidin 5'-phosphate …
Matched Iupac: … -3-yl]-2-[N-hydroxy-N-(hydroxymethyl)amino]pentanoic acid ... (2S)-5-[(5S,7R,8S,9R)-8,9-dihydroxy-2,4-dioxo-7-[(phosphonooxy)methyl]-6-oxa-1,3-diazaspiro[4.4]nonan …
Experimental
Matched Name: … Bis(Adenosine)-5'-Triphosphate …
Matched Iupac: … bis[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
Experimental
Matched Name: … Deoxyuridine-5'-Triphosphate …
Matched Iupac: … ({[({[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy …
Experimental
Matched Name: … 6-hydroxyuridine-5'-phosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy …
Experimental
Matched Name: … 5-Bromothienyldeoxyuridine …
Matched Iupac: … 5-(5-bromothiophen-2-yl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine …
Experimental
Matched Name: … Adenosine-5'-Propylphosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(propoxy)phosphinic acid …
Experimental
Matched Iupac: … N,N,N-trimethyl-3-(2,2,2-trifluoro-1,1-dihydroxyethyl)anilinium …
Experimental
Matched Iupac: … N-[(2R)-2-{4'-[(2R)-1-methanesulfonamidopropan-2-yl]-[1,1'-biphenyl]-4-yl}propyl]methanesulfonamide …
Experimental
Matched Name: … N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(2-hydroxyethyl)glycinamide …
Matched Iupac: … N-hydroxy-2-[N-(2-hydroxyethyl)[1,1'-biphenyl]-4-sulfonamido]acetamide …
Narasin is an agent with coccidiostatic and antibacterial properties.
Experimental
Vet approved
Matched Iupac: … ]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-3,5-dimethyloxan-2-yl]butanoic acid ... -methyloxan-2-yl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5^{7}.3^{5}]pentadec-13-en-9-yl ... (2R)-2-[(2R,3S,5S,6R)-6-[(2S,3S,4S,6R)-6-[(2S,5S,7R,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-ethyl-5-hydroxy-6 …
Malacidin A, along with DB14052, is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria . Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. While structurally similar to other macrocycle drugs like DB00080 and DB06087, Malacidin A...
Experimental
Matched Iupac: … [2,1-c]1,4,7,10,13,16,19,22,25-nonaazacyclooctacosan-4-yl]carbamoyl}-2-methyl-3-[(2E,4Z)-8-methylnona ... (3S)-3-{[(4S,7R,10S,13S,16S,22R,25S,29R,30aS)-10-(4-aminobutyl)-13-[carboxy(hydroxy)methyl]-22-(1-carboxyethyl ... )-16-(carboxymethyl)-3,29-dimethyl-1,5,8,11,14,17,20,23,26-nonaoxo-7,25-bis(propan-2-yl)-triacontahydropyrrolo …
Malacidin B, along with DB14051, is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria . Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. While structurally similar to other macrocycle drugs like DB00080 and DB06087, Malacidin B...
Experimental
Matched Iupac: … [2,1-c]1,4,7,10,13,16,19,22,25-nonaazacyclooctacosan-4-yl]carbamoyl}-2-methyl-3-[(2E,4Z)-8-methyldeca ... (3S)-3-{[(4S,7R,10S,13S,16S,22R,25S,29R,30aS)-10-(4-aminobutyl)-13-[carboxy(hydroxy)methyl]-22-(1-carboxyethyl ... )-16-(carboxymethyl)-3,29-dimethyl-1,5,8,11,14,17,20,23,26-nonaoxo-7,25-bis(propan-2-yl)-triacontahydropyrrolo …
Experimental
Matched Iupac: … (2S)-2-{[4-({[(6S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic …
Experimental
Matched Synonyms: … Adenosine 5'-(hydrogen (phosphonomethyl)phosphonate) ... Adenosine, 5'-(trihydrogen methylenebis(phosphonate)) …
Matched Name: … Adenosine 5'-methylenediphosphate …
Matched Iupac: … [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)methyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... 5'-Nucleotidase, antagonists & inhibitors …
Experimental
Matched Synonyms: … 2-chloro-1-hydroxybenzene …
Matched Name: … 2-Chlorophenol …
Matched Iupac: … 2-chlorophenol …
Thallium Tl-201 is under investigation in clinical trial NCT02697760 (The CZT Dynamic Myocardial Perfusion Imaging).
Investigational
Displaying drugs 8476 - 8500 of 11262 in total