(6S)-5,6,7,8-tetrahydrofolic acid

DB02031ExperimentalSmall molecule

(6S)-5,6,7,8-tetrahydrofolic acid: Overview.

Chemical structure of (6S)-5,6,7,8-tetrahydrofolic acid
Formula / weight
C19H23N7O6 · 445.4292 g/mol (avg)
Also known as
(6S)-5,6,7,8-tetrahydrofolate · (6S)-H4folate · (6S)-tetrahydrofolate · (6S)-Tetrahydrofolic acid · (6S)-THFA

Resolves to

Structure
InChIKeyMSTNYGQPCMXVAQ-RYUDHWBXSA-NSMILESNC1=NC2=C(N[C@@H](CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CN2)C(=O)N1

What you can answer from here — as of September 16, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
33Drug interactionsStructured to mechanism, not free text
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5+ReferencesStructured and connected to the statements they support
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Which drugs share a target with (6S)-5,6,7,8-tetrahydrofolic acid, and which of those have an active Phase 3 trial?

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