Displaying drugs 8601 - 8625 of 9757 in total
Alflutinib
Alflutinib is under investigation in clinical trial NCT03452592 (Efficacy and Safety of Alflutinib in Locally Advanced or Metastatic Non-small Cell Lung Cancer Patients With T790M).
Investigational
Matched Iupac: … -trifluoroethoxy)pyridin-3-yl)prop-2-enamide ... N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}-6-(2,2,2 …
Mavelertinib
Mavelertinib is under investigation in clinical trial NCT02349633 (Study for Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M)).
Investigational
Matched Iupac: … -3-yl]prop-2-enamide ... N-[(3R,4R)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl}pyrrolidin …
Pyridoxamine-5'-Phosphate
Experimental
Matched Iupac: … {[4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl]methoxy}phosphonic acid …
Pyridoxine phosphate
Experimental
Matched Iupac: … {[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methoxy}phosphonic acid …
Lpc-Ether
Experimental
Matched Iupac: … [(2R)-2-hydroxy-3-(octadecyloxy)propoxy][2-(trimethylazaniumyl)ethoxy]phosphinic acid …
4-Methyl-Pyrroline-5-Carboxylic Acid
Experimental
Matched Iupac: … (2R,3R)-3-methyl-2,3-dihydro-1H-pyrrole-2-carboxylic acid …
VX-702
VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases, specifically rheumatoid arthritis (RA). It acts as a p38 MAP kinase inhibitor. In the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA.
Investigational
Matched Iupac: … 2-(2,4-difluorophenyl)-6-[1-(2,6-difluorophenyl)carbamoylamino]pyridine-3-carboxamide …
Naluzotan
Investigational
Matched Iupac: … N-(3-{4-[4-(cyclohexylmethanesulfonamido)butyl]piperazin-1-yl}phenyl)acetamide …
Levopropoxyphene
Levopropoxyphene is a stereoisomer of propoxyphene in the form of 2S, 3R enantiomer. It was sold as an antitussive, but it was removed from the market in the 70s. Levopropoxyphene was developed by Lilly and FDA approved on March 21st, 1962. This drug presented different dosages and it was administered...
Withdrawn
Matched Iupac: … (2R,3S)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl propanoate …
CYCLOHEXYL-NORSTATINE
Experimental
Matched Iupac: … propan-2-yl (2R,3S)-3-amino-4-cyclohexyl-2-hydroxybutanoate …
Decoquinate
Decoquinate is used in veterinary to delay the growth and reproduction of coccidian parasites.
Experimental
Vet approved
Matched Iupac: … ethyl 6-(decyloxy)-7-ethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate …
Talsaclidine
Talsaclidine has been used in trials studying the treatment of Alzheimer Disease.
Investigational
Matched Iupac: … (3R)-3-(prop-2-yn-1-yloxy)-1-azabicyclo[2.2.2]octane …
Liarozole
Liarozole has been used in trials studying the treatment of Ichthyosis, Lamellar.
Investigational
Matched Iupac: … 6-[(3-chlorophenyl)(1H-imidazol-1-yl)methyl]-1H-1,3-benzodiazole …
Tiropramide
Tiropramide is under investigation in clinical trial NCT01629212 (Comparison of the Efficacy and Safety of Tiropramide and Octylonium in the Treatment of Irritable Bowel Syndrome).
Investigational
Matched Iupac: … 3-{4-[2-(diethylamino)ethoxy]phenyl}-2-(phenylformamido)-N,N-dipropylpropanamide …
Stibophen
Stibophen is used in the treatment of schistosomiasis, a disease of parasitic flatworms.
Experimental
Matched Iupac: … antimony(3+) ion pentasodium bis(3,5-disulfobenzene-1,2-bis(olate)) heptahydrate …
Benzilone
Experimental
Matched Iupac: … 1,1-diethyl-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]pyrrolidin-1-ium …
Prenoxdiazine
Experimental
Matched Iupac: … 1-{2-[3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl]ethyl}piperidine …
Etybenzatropine
Experimental
Matched Iupac: … (1R,3S,5S)-3-(diphenylmethoxy)-8-ethyl-8-azabicyclo[3.2.1]octane …
Oxantel
Experimental
Matched Iupac: … 3-[(E)-2-(1-methyl-1,4,5,6-tetrahydropyrimidin-2-yl)ethenyl]phenol …
Proxazole
Experimental
Matched Iupac: … diethyl({2-[3-(1-phenylpropyl)-1,2,4-oxadiazol-5-yl]ethyl})amine …
Indigo
Experimental
Investigational
Matched Iupac: … (E)-1H,1'H,3H,3'H-[2,2'-biindolylidene]-3,3'-dione …
Diprenorphine
A narcotic antagonist similar in action to naloxone. It is used to remobilize animals after etorphine neuroleptanalgesia and is considered a specific antagonist to etorphine. [PubChem]
Illicit
Vet approved
Matched Iupac: … (1S,2R,6S,14R,15R,16R)-3-(cyclopropylmethyl)-16-(2-hydroxypropan-2-yl)-15-methoxy-13-oxa-3-azahexacyclo …
Sufugolix
Investigational
Matched Iupac: … [2,3-d]pyrimidin-6-yl)phenyl]-3-methoxyurea ... 1-[4-(5-{[benzyl(methyl)amino]methyl}-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenyl-1H,2H,3H,4H-thieno …
Bis-Benzamidine
Experimental
Matched Iupac: … 4-{[(1S,3S)-3-[(4-carbamimidoylphenyl)methyl]-2-oxocycloheptyl]methyl}benzene-1-carboximidamide …
Metanitrophenyl-Alpha-D-Galactoside
Experimental
Matched Iupac: … (2R,3R,4S,5R,6R)-2-(hydroxymethyl)-6-(3-nitrophenoxy)oxane-3,4,5-triol …
Displaying drugs 8601 - 8625 of 9757 in total