Displaying drugs 8601 - 8625 of 10989 in total
GLPG-0492
Glpg0492 is under investigation in clinical trial NCT01130818 (First-in-Human Single Ascending Dose of GLPG0492).
Investigational
Matched Iupac: … 4-[(4S)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile …
Tunlametinib
Investigational
Matched Synonyms: … 4-fluoro-5-((2-fluoro-4-iodophenyl)amino)-n-(2-hydroxyethoxy)-6-benzothiazolecarboxamide ... 6-benzothiazolecarboxamide, 4-fluoro-5-((2-fluoro-4-iodophenyl)amino)-n-(2-hydroxyethoxy)- …
Homogentisic acid
Experimental
Azapentacene
Experimental
AZD-1940
Investigational
Matched Synonyms: … Ethanesulfonamide, n-(1-((4,4-difluorocyclohexyl)methyl)-2-(1,1-dimethylethyl)-1h-benzimidazol-5-yl)- …
Matched Iupac: … N-{2-tert-butyl-1-[(4,4-difluorocyclohexyl)methyl]-1H-1,3-benzodiazol-5-yl}ethane-1-sulfonamide …
Matched Iupac: … N-{2-tert-butyl-1-[(4,4-difluorocyclohexyl)methyl]-1H-1,3-benzodiazol-5-yl}ethane-1-sulfonamide …
2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone
Experimental
Matched Iupac: … N-[(3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-oxooxan-3-yl]acetamide …
4'-Methylene-5,8,10-trideazaaminopterin
CH-1504 is a an antirheumatic agent that has been shown in vitro to be a nonpolyglutamylatable and nonhydroxylatable antifolate that is more efficiently taken up into cells by the reduced folate carrier (RFC) system than is Methotrexate. It has been investigated for the treatment of Rheumatoid Arthritis (phase II).
Investigational
Isatin
Isatin is an indole derivative first obtained by Erdman and Laurent in 1841 as an oxidation product of Indigo dye with nitric acid and chromic acids. The compound is found in many plants and Schiff bases of Isatin are have been investigated for pharmaceutical applications.
Experimental
Eptacog alfa pegol (activated)
Eptacog alfa pegol (activated) has been used in trials studying the prevention and treatment of Haemophilia A, Haemophilia B, Congenital Bleeding Disorder, Haemophilia B With Inhibitors, and Haemophilia A With Inhibitors.
Investigational
Acetylleucine
Used for treating vestibular-related imbalance and vertigo.
Experimental
Matched Synonyms: … (R,S)-N-Acetylleucin …
BT200
BT200 (Rondoraptivon pegol) is a PEGylated anti-von Willebrand factor (VWF) aptamer targeted against the VWF A1 domain. It is under investigation for the treatment of von Willebrand disease and hemophilia A.
Investigational
Pantothenoylaminoethenethiol
Experimental
OCU-100
Investigational
Bis(5-Amidino-Benzimidazolyl)Methane
Experimental
Matched Name: … Bis(5-Amidino-Benzimidazolyl)Methane …
4-Hydroxy-L-Threonine-5-Monophosphate
Experimental
Matched Name: … 4-Hydroxy-L-Threonine-5-Monophosphate …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-4-(phosphonooxy)butanoic acid …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-4-(phosphonooxy)butanoic acid …
Endothelin-1
Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin).
Investigational
Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine
Experimental
Matched Name: … Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine …
Matched Iupac: … (2S)-2-[(2R)-2-{[(2R,3R,4R,5S,6R)-2-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl ... )-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3-acetamido-5-hydroxy …
Matched Iupac: … (2S)-2-[(2R)-2-{[(2R,3R,4R,5S,6R)-2-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl ... )-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3-acetamido-5-hydroxy …
Palmitoyl-Linoleoyl Phosphatidylcholine
Experimental
Matched Iupac: … (2-{[(2R)-3-(hexadecanoyloxy)-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]propyl phosphonato]oxy}ethyl)trimethylazanium …
D-Phenylalanine
An essential aromatic amino acid that is a precursor of melanin; dopamine; noradrenalin (norepinephrine), and thyroxine. [PubChem]
Experimental
Matched Iupac: … (2R)-2-amino-3-phenylpropanoic acid …
Ertiprotafib
Ertiprotafib belongs to a novel class of insulin sensitizers developed for treatment of type 2 diabetes. In insulin-resistant rodent models, ertiprotafib and a close analog lowered both fasting blood glucose and insulin levels and improved glycemic excursion during an oral glucose tolerance test.
Investigational
Matched Iupac: … (2R)-2-(4-{9-bromo-2,3-dimethylnaphtho[2,3-b]thiophen-4-yl}-2,6-dimethylphenoxy)-3-phenylpropanoic acid …
N-(carboxycarbonyl)-D-phenylalanine
N-(carboxycarbonyl)-D-phenylalanine is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. It targets the protein hypoxia-inducible factor 1-alpha inhibitor.
Experimental
Matched Iupac: … (2R)-2-(carboxyformamido)-3-phenylpropanoic acid …
Acetyldihydrocodeine
Experimental
Illicit
Matched Iupac: … (1S,5R,13R,14S,17R)-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Trehalose-6-Phosphate
Experimental
Matched Iupac: … {[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] …
Displaying drugs 8601 - 8625 of 10989 in total